LEAK state without adenylates: Difference between revisions

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==State 2==
== The LEAK state of respiration: towards a concept-linked terminology of respiratory states ==
 
* ''More details:'' >> [[LEAK respiration]]
[[State 2]] was re-defined as functionally the same as [[State 4]] (Nicholls and Ferguson 2002). State 2 (Chance and Williams 1955, 1956), however, is substrate-limited residual oxygen consumption at high ADP (ROX<sub>D</sub>), whereas ''L''<sub>N</sub> and ''L''<sub>T</sub> (State 4) are LEAK states in the absence of adenylates (''L''<sub>N</sub>: no ADP, no ATP) or presence of ATP (''L''<sub>T</sub>).

Revision as of 11:27, 20 April 2014


high-resolution terminology - matching measurements at high-resolution


LEAK state without adenylates

Description

In the LEAK state without adenylates, LN (N for no adenylates), mitochondrial respiration is measured after addition of substrates, which decreases slowly to the LEAK state after oxidation of endogenous substrates with no adenylates.

Abbreviation: LN

Reference: Gnaiger 2012 MitoPathways


MitoPedia methods: Respirometry 


MitoPedia topics: "Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. Respiratory state"Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. 

The LEAK state of respiration: towards a concept-linked terminology of respiratory states

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