Difference between revisions of "MitoEAGLE data: muscle"
From Bioblast
Line 34: | Line 34: | ||
:::# Draft a comprehensive review on mt-function in muscle tissue (registration at PROSPERO, link with EQUATOR). | :::# Draft a comprehensive review on mt-function in muscle tissue (registration at PROSPERO, link with EQUATOR). | ||
:::# Opening of the database to the research public for data search and moderated entry of new data sets. | :::# Opening of the database to the research public for data search and moderated entry of new data sets. | ||
Line 47: | Line 48: | ||
:::# Draft of review manuscript. | :::# Draft of review manuscript. | ||
== WG2 Feedback == | |||
::::# ''Skeletal muscle is the main tissue we are studying in the lab.'' - '''[[Chabi B|Beatrice Chabi]]''' (2016). | |||
::::# ''For the kind of work group, our expertise is certainly most on muscle tissue (skeletal and heart), although we also worked on all kinds of permeabilized cells (primary cells and cell lines). For all these, we have extended data sets, mainly rat, but also human, from diverse experimental setups (nutritional regimen, exercise, drugs ...).'' - '''[[Schlattner U|Uwe Schlattner]]''' (2016). | |||
::::# ''I would fit rather in WG1, as myself I am not involved in human muscle fat or blood. However, in our team we made a study involving human liver samples.'' - '''[[Bouillaud F|Frédéric Bouillaud ]]''' (2016). | |||
::::# ''In my working group we are mainly interested in muscle, especially focusing on aging and sarcopenia (using animal models). I would be happy if new cooperations could be formed through the COST Action. I could imagine working on a joint review article. Next to examining muscle from mouse models, we are studying biopsies from human heart muscle and liver, but there is no published data on these studies yet.'' - '''[[Klaus S| Susanne Klaus]]''' (2016). ''Translated by Sandra Fleischmann'' | |||
::::# ''I am very interested in being part of the management committee either as a MC member for managment tasks or in working group 4 MITOEAGLE data repository for blood cells and cultured cells. I have experience in analyzing mitochondrial function in different human tissues as cultured cells and blood cells (also subsets of specific blood populations, see list of publications), muscle and isolated mitochondria. This together with my experience in organizing summer schools and conferences could be helpful as MC member taking care of management tasks. However, if you think my expertise is more helpful in working group 4, I am looking forward to support this working group.'' - [[Renner-Sattler K|Kathrin Renner-Sattler]] (2016). | |||
::::# ''I am working in the field of mitochondrial biochemistry since many years. In detail my coworkers and I are carrying out studies on the regulation of ATP synthase and respiratory complexes in swine heart mitochondria as biological model of mammalian mitochondria. Some comparative aspects of mitochondrial bioenergetics and ATP synthase responses are also investigated in bivalve mollusk mitochondria.'' - '''[[Pagliarani A|Alessandra Pagliarani]]''' (2016). | |||
== Projects in progress == | == Projects in progress == |
Revision as of 15:15, 2 May 2016
News and Events | Working Groups | Short-Term Scientific Missions | Management Committee | Members |
COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
MitoEAGLE data: muscle
WG2
- MITOEAGLE data repository in muscle and other tissues
WG2 Description
- During the past 10 years, a dramatically increasing number of studies report respirometric data on human muscle tissue (e.g. Christiansen 2015 Am J Physiol). Muscle mitochondrial function is particularly studied in genetically engineered mouse models of human diseases (e.g. Jelenik 2014 Diabetes). However, despite the many published data, lack of consistency often precludes quantitative comparison among data sets with permeabilized or homogenized muscle fibres or isolated mitochondria, normalized to either tissue wet weight, dry weight, protein content, citrate synthase activity or other mitochondrial markers. In the absence of validated conversion factors, these data remain largely unconnected and can only be qualitatively linked.
- The aim of WG2 will be to provide access to complete data sets for post-study statistical analysis and use harmonization tools (WG1) for standardized documentation, to initiate a data repository on muscle tissue from humans and model organisms in health and disease. Data sets shall be obtained from already published and new studies, prompting participating labs to report experimental details beyond those already published as far as possible (using tools such as PubMed Commons). As a result, specific protocols will be summarized for handling muscle tissue. Depending on specific interests, WG2 may decide to extend their focus to other tissue types.
WG2 Participants
Country | City | Contact |
---|---|---|
Australia | Melbourne | Bishop David J |
Austria | Innsbruck | Gnaiger Erich |
Austria | Salzburg | Mayr JA |
Austria | Innsbruck | Doerrier Carolina |
Austria | Innsbruck | Laner Verena |
Belgium | Leuven | Bird Matthew |
Belgium | Liege | Votion Dominique-Marie |
Brazil | Jaboticabal, SP | Garcia Geovana S |
Brazil | São Paulo | Ferreira Julio Cesar B |
Canada | Rimouski | Vandermeeren E |
Canada | Vancouver | Boushel Robert C |
Canada | Edmonton (Alberta) | Lemieux Helene |
Canada | Rimouski | Blier Pierre U |
Canada | Antigonish | Kane Daniel A |
Croatia | Zagreb | Saric A |
Croatia | Split | Mihanovic I |
Czech Republic | Pilsen | Kuncova J |
Czech Republic | Hradec Králové | Waldauf P |
Czech Republic | Pilsen | Markova Michaela |
Czech Republic | Prague | Elkalaf Moustafa |
Czech Republic | Prague 10 | Krajcova Adela |
Denmark | Hvidovre | Nehlin Jan O |
Denmark | Copenhagen | Gonzalez-Franquesa Alba |
Denmark | Malov | Hey-Mogensen M |
Denmark | Copenhagen | Dela Flemming |
Denmark | Copenhagen N | Mortensen OH |
Denmark | Copenhagen | Larsen Steen |
Estonia | Tallinn | Puurand Marju |
Estonia | Tallinn | Truu Laura |
Estonia | Tallinn | Kaambre Tuuli |
Estonia | Tallinn | Tepp Kersti |
Estonia | Tallinn | Aid-Vanakova Jekaterina |
Estonia | Tallinn | Vendelin Marko |
Estonia | Tallinn | Karro N |
Estonia | Tartu | Paju Kalju |
Finland | Helsinki | Pirinen E |
Finland | Jyvaeskylae | Lehti Maarit |
France | Paris | Armand Anne-Sophie |
France | Paris | Petit Patrice X |
France | Bordeaux cedex | Mourier A |
France | Grenoble Cedex 9 | Schlattner Uwe |
France | Montpellier Cedex 1 | Chabi Beatrice |
France | Grenoble cedex 9 | Dubouchaud Herve |
France | Paris | Ventura-Clapier R |
France | Montpellier | Cortade F |
Germany | Duesseldorf | Roden Michael |
Germany | Köln | Kimoloi Sammy |
Germany | Düsseldorf | Granata Cesare |
Germany | Duesseldorf | Jelenik T |
Germany | Bremerhaven | Mark Felix Christopher |
Germany | Leipzig | Ost Mario |
Germany | Cologne | Pesta Dominik |
Germany | Rostock | Haider F |
Germany | Nuthetal | Klaus S |
Germany | Munich | Jastroch M |
Germany | Bochum | Platen P |
Greece | Heraklio | Sidiropoulou K |
Greece | Athens | Trougakos Ioannis P |
Greece | Heraklion | Tavernarakis Nektarios |
India | Haryana | Sharma Vipin |
Ireland | Sligo | Murphy J |
Ireland | Dublin | O'Gorman Donal |
Ireland | Dublin | Porter Richard K |
Israel | Rishon Le Zion | Hachmo Yafit |
Israel | Zrifin | Sova Marina |
Israel | Jerusalem | Saada Reisch Ann |
Italia | Udine | Salvadego Desy |
Italy | Milan | Giovarelli Matteo |
Italy | Bologna | Genova Maria Luisa |
Italy | Pisa | Gastaldelli Amalia |
Italy | Novara | Reano Simone |
Italy | Rome | Scatena Roberto |
Italy | Milan | De Palma Clara |
Japan | Sapporo | Shirakawa R |
Japan | Sapporo | Nambu H |
Japan | Sapporo | Maekawa S |
Latvia | Riga | Liepins Edgars |
Latvia | Riga | Kuka Janis |
Latvia | Riga | Zvejniece Liga |
Latvia | Riga | Inashkina I |
Luxembourg | Strassen | Devaux Yvan |
Malta | Msida | Vella Joanna |
Netherlands | Amsterdam | De Goede Paul |
Netherlands | Maastricht | Hoeks Joris |
Netherlands | BT Amsterdam | Jaspers Richard T |
Netherlands | Maastricht | Grevendonk L |
Netherlands | Wageningen | Keijer Jaap |
Netherlands | Maastricht | Van Polanen N |
Niederlande | ER Masstricht | De Wit-Verheggen V |
Niederlande | ER Masstricht | De Theije C |
Norway | Tromsoe | Aasum E |
Norway | Oslo | Torp May-Kristin |
Norway | Oslo | Nikolic N |
Norway | Tromsoe | Jansen Kirsten M |
Norway | Oslo | Rustan AC |
Norway | Oslo | Eide L |
Norway | Bergen | Tronstad Karl Johan |
Norway | Tromsoe | Larsen Terje S |
Norway | Tromsoe | Schots Pauke C |
Norway | Ullevål | Heiestad Christina |
Norway | Oslo | Lund Jenny |
Poland | Lodz | Watala Cezary |
Poland | Lodz | Labieniec-Watala Magdalena |
Poland | Warsaw | Sek Aleksandra |
Poland | Warsaw | Kampa Rafal Pawel |
Poland | Warsaw | Dymkowska Dorota |
Portugal | Coimbra | Pereira Susana P |
Portugal | Coimbra | Carvalho Eugenia |
Portugal | Porto | Beleza Jorge |
Portugal | Cantanhede | Martins Joao D |
Portugal | Cantanhede | Ferreira LL |
Portugal | Coimbra | Martins Marques T |
Portugal | Coimbra | Palmeira Carlos |
Portugal | Porto | Coxito Pedro |
Portugal | Porto | Magalhaes Jose |
Romania | Timisoara | Lighezan R |
Romania | Timisoara | Muntean Danina M |
Singapore | Singapore | Hausenloy Derek J |
Slovakia | Bratislava | Ukropec J |
Slovakia | Bratislava | Sumbalova Zuzana |
Slovakia | Bratislava | Ukropcova B |
Slovakia | Bratislava | Maderova D |
Slovakia | Bratislava | Nemec Michal |
Slovenia | Ljubljana | Mars T |
Slovenia | Ljubljana | Pirkmajer Sergej |
Slovenia | Ljubljana | Dolinar K |
South Africa | Smith James | |
Spain | Barcelona | Batlle M |
Spain | Armilla (Granada) | Fernandez-Ortiz Marisol |
Spain | Armilla (Granada) | Acuna-Castroviejo Dario |
Spain | Barcelona | Gama Perez Pau |
Spain | Armilla, Granada | Escames Germaine |
Spain | A Coruña | Blanco FJ |
Spain | Barcelona | Garcia-Roves Pablo Miguel |
Spain | Barcelona | Guitart M |
Spain | Granada | Lopez Garcia Luis Carlos |
Spain | Madrid | Cadenas S |
Spain | Madrid | Moran M |
Spain | Barcelona | Sebastian D |
Spain | Barcelona | De la Torre Lara J |
Spain | Sevilla | Bustos Matilde |
Spain | Barcelona | Zorzano Antonio |
Spain | Barcelona | Catalan M |
Sweden | Linköping | Fontes-Oliveira CC |
Sweden | Stockholm | Cardinale Daniele A |
Switzerland | Lausanne | Morato Fornaguera L |
Switzerland | Bern | Nuoffer Jean-Marc |
Switzerland | Lausanne | Sandi Carmen |
Switzerland | Lausanne | Weger M |
Switzerland | Lausanne | Zalachoras I |
Switzerland | Lausanne | Gebara E |
The Netherlands | Wageningen | Van der Ende Miranda |
The Netherlands | BT Amsterdam | Wuest Rob CI |
Turkey | Ankara | Tuncay Erkan |
USA | Ann Arbor | Beard Daniel A |
USA | Orlando | Distefano Giovanna |
USA | Boca Raton | Khamoui Andy V |
USA | Little Rock | Porter Craig |
USA | St Louis | Welch R |
USA | Baton Rouge | Axelrod Christopher L |
USA | Gainesville | Wohlgemuth Stephanie E |
USA | Gainesville | Neyroud D |
USA | College Station | Latham C |
USA | Chicago | Dayanidhi Sudarshan |
USA | Orlando | Coen Paul M |
USA | Baton Rouge | Irving Brian A |
USA | Fairbanks | O'Brien Kristin |
USA | Torrance | Rossiter Harry B |
USA | Baltimore | Gonzalez-Freire Marta |
USA | College Station | White-Springer Sarah H |
USA | Fort Collins | Chicco Adam J |
USA | Colorado Springs | Jacobs RA |
USA | Norfolk | Lai Nicola |
USA | Gainesville | Hepple Russell T |
USA | Seattle | Marcinek DJ |
USA | Baltimore | Fang Evandro F |
United Kingdom | Birmingham | Joanisse S |
United Kingdom | Manchester | Giakoumaki I |
United Kingdom | London | Szabadkai Gyorgy |
United Kingdom | Loughborough | Ebanks Brad |
United Kingdom | Birmingham | Garten Antje |
United Kingdom | Plymouth, Devon | McKenna Helen T |
United Kingdom | Birmingham | Thakker A |
United Kingdom | Leeds | Boyle JP |
United Kingdom | Cambridge | Shiroma Jonathan G |
United Kingdom | Brighton | Moore Anthony L |
United Kingdom | Nottingham | Chakrabarti Lisa |
United Kingdom | Cambridge | Murray Andrew James |
United Kingdom | Birmingham | Ashcroft S |
United Kingdom | Oxford | Makrecka-Kuka Marina |
United States | Providence | Siamwala J |
WG2 Management
Tasks
- Call for participating labs to deliver relevant experimental data on already published studies and to report them in a standardized format.
- Collection and indexing of the data sets as required for statistical analysis.
- Discussion of procedures, protocols and general guidelines.
- Draft a comprehensive review on mt-function in muscle tissue (registration at PROSPERO, link with EQUATOR).
- Opening of the database to the research public for data search and moderated entry of new data sets.
Milestones
- Call for data report delivered.
- Data sets entered in standardized format.
- Summary, interpretation and discussion of data for review.
Deliverables
- A MITOEAGLE database on muscle tissue from humans and model organisms.
- A set of guidelines for future studies on mitochondrial bioenergetics in muscle tissue.
- Draft of review manuscript.
WG2 Feedback
- Skeletal muscle is the main tissue we are studying in the lab. - Beatrice Chabi (2016).
- For the kind of work group, our expertise is certainly most on muscle tissue (skeletal and heart), although we also worked on all kinds of permeabilized cells (primary cells and cell lines). For all these, we have extended data sets, mainly rat, but also human, from diverse experimental setups (nutritional regimen, exercise, drugs ...). - Uwe Schlattner (2016).
- I would fit rather in WG1, as myself I am not involved in human muscle fat or blood. However, in our team we made a study involving human liver samples. - Frédéric Bouillaud (2016).
- In my working group we are mainly interested in muscle, especially focusing on aging and sarcopenia (using animal models). I would be happy if new cooperations could be formed through the COST Action. I could imagine working on a joint review article. Next to examining muscle from mouse models, we are studying biopsies from human heart muscle and liver, but there is no published data on these studies yet. - Susanne Klaus (2016). Translated by Sandra Fleischmann
- I am very interested in being part of the management committee either as a MC member for managment tasks or in working group 4 MITOEAGLE data repository for blood cells and cultured cells. I have experience in analyzing mitochondrial function in different human tissues as cultured cells and blood cells (also subsets of specific blood populations, see list of publications), muscle and isolated mitochondria. This together with my experience in organizing summer schools and conferences could be helpful as MC member taking care of management tasks. However, if you think my expertise is more helpful in working group 4, I am looking forward to support this working group. - Kathrin Renner-Sattler (2016).
- I am working in the field of mitochondrial biochemistry since many years. In detail my coworkers and I are carrying out studies on the regulation of ATP synthase and respiratory complexes in swine heart mitochondria as biological model of mammalian mitochondria. Some comparative aspects of mitochondrial bioenergetics and ATP synthase responses are also investigated in bivalve mollusk mitochondria. - Alessandra Pagliarani (2016).
Projects in progress
- » MiPMap