O2k-PublicationAlert2020 Archive

» Listed in Oroboros Ecosystem Agenda 2020

May 2020

• May-12 Tu

Mitochondria - a driving force in adipocyte differentiation from the O2k-Network »CZ Pilsen Kuncova J« Kladnická I, Čedíková M, Kripnerová M, Dvořáková J, Kohoutová M, Tůma Z, Müllerová D, Kuncová J (2019) Mitochondrial respiration of adipocytes differentiating from human mesenchymal stem cells derived from adipose tissue. Physiol Res 68:287-96. »Bioblast link«

• May-05 Tu

Expression of alternative oxidase prevents reverse electron transfer formation in heart mitochondria isolated from mouse from the O2k-Network »FI Helsinki Jacobs HT«  »DE Magdeburg Gellerich FN« »FI Tampere Dufour E« »DE Magdeburg Debska-Vielhaber G« »DE Frankfurt Wittig I« and »UK Brighton Moore AL« Szibor Marten, Gainutdinov Timur, Fernandez-Vizarra Erika, Dufour Eric, Gizatullina Zemfira, Debska-Vielhaber Grazyna, Heidler Juliana, Wittig Ilka, Viscomi Carlo, Gellerich Frank Norbert, Moore Anthony L (2019) Bioenergetic consequences from xenotopic expression of a tunicate AOX in mouse mitochondria: switch from RET and ROS to FET. Biochim Biophys Acta Bioenerg 1861:148137. »Bioblast link«

Apr 2020

• Apr-28 Tu

The mitochondrial gas pedal: Cytosolic calcium controls extramitochondrial pyruvate generation and mitochondrial pyruvate uptake from the O2k-Network » FI Helsinki Jacobs HT « » DE Magdeburg Gellerich FN « and »DE Magdeburg Debska-Vielhaber G« Szibor Marten, Gizatullina Zemfira, Gainutdinov Timur, Endres Thomas, Debska-Vielhaber Grazyna, Kunz Matthias, Karavasili Niki, Hallmann Kerstin, Schreiber Frank, Bamberger Alexandra, Schwarzer Michael, Doenst Torsten, Heinze Hans-Jochen, Leßmann Volkmar, Vielhaber Stefan, Kunz Wolfram S, Gellerich Frank Norbert (2020) Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply. J Biol Chem [Epub ahead of print]. »Bioblast link«

• Apr-20 Mo

The effect of respiration buffer composition on mitochondrial metabolism and function from the O2k-Network »US TN Nashville Wasserman DH« and »US MI East Lansing Bazil JN« Wollenman LC, Vander Ploeg MR, Miller ML, Zhang Y, Bazil JN (2017) The effect of respiration buffer composition on mitochondrial metabolism and function. PLOS ONE 12:e0187523. - »Bioblast link«

• Apr-15 Mo

Respiratory analysis of coupled mitochondria in cryopreserved liver biopsies from the O2k-Network »UY Montevideo Radi R« García-Roche M, Casal A, Carriquiry M, Radi R, Celia Quijano C, Cassina A (2018) Respiratory analysis of coupled mitochondria in cryopreserved liver biopsies. Redox Biol 17:207-12. - »Bioblast link«

• Apr-06 Mo

Physical activity has positive effects on mitochondria from patients with occupational burnout from the O2k-Network »CH Basel Eckert A« Brand S, Ebner K, Mikoteit T, Lejri I, Gerber M, Beck J, Holsboer-Trachsler E, Eckert A (2020) Influence of regular physical activity on mitochondrial activity and symptoms of burnout - an interventional pilot study. J Clin Med 9:E667. - »Bioblast link«

• Apr-03 Fr

Novel diurnal action of of mitochondrial stress-induced GDF15 in systemic metabolism regulation from the O2k-Network »DE Nuthetal Klaus S« Ost M, Igual Gil C, Coleman V, Keipert S, Efstathiou S, Vidic V, Weyers M, Klaus S (2020) Muscle-derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress. EMBO Rep [Epub ahead of print]. - »Bioblast link«

• Apr-01 We

Parkinson’s Disease Awareness Month: Dominant mutation in Parkinson’s Disease causes loss of protein function in mitochondria from the O2k-Network »FR Angers Gueguen N« and »BE Leuven Spinazzi M« Cornelissen T, Spinazzi M, Martin S, Imberechts D, Vangheluwe P, Bird M, De Strooper B, Vandenberghe W (2020) CHCHD2 harboring the Parkinson's disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2. Hum Mol Genet [Epub ahead of print]. »Bioblast link«

Mar 2020

• Mar-20 Fr

High-resolution respirometry in human prostate cancer biopsies and mtDNA analyzed in samples recovered from the O2k-chamber from the O2k-Network »AT Innsbruck Oroboros« Schöpf Bernd, Weissensteiner Hansi, Schäfer Georg, Fazzini Federica, Charoentong Pornpimol, Naschberger Andreas, Rupp Bernhard, Fendt Liane, Bukur Valesca, Giese Irina, Sorn Patrick, Sant’Anna-Silva Ana Carolina, Iglesias-Gonzalez Javier, Sahin Ugur, Kronenberg Florian, Gnaiger Erich, Klocker Helmut (2020) OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. Nat Commun 2020-03-20 [Epub ahead of print]. - »Bioblast link«

• Mar-12 Th

Multiple Sclerosis Month: Mitochondrial permeability transition pore protection as novel therapeutic approach in multiple sclerosis from the O2k-Network »UK London Duchen MR« Warne J, Pryce G, Hill J, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AW, Towers GJ, Coker A, Duchen MR, Szabadkai G, Baker D, Selwood D (2015) Selective inhibition of the mitochondrial permeability transition pore protects against neuro-degeneration in experimental multiple sclerosis. J Biol Chem 291:4356-73. - »Bioblast link«

• Mar-10 Tu

Muscular exercise for training adipose tissue mitochondria from the O2k-Network »DK Copenhagen Larsen S« Mendham Amy E, Larsen Steen, George Cindy, Adams Kevin, Hauksson Jon, Olsson Tommy, Fortuin-de Smidt Melony C, Nono Nankam Pamela A, Hakim Olah, Goff Louise M, Pheiffer Carmen, Goedecke Julia H (2020) Exercise training results in depot-specific adaptations to adipose tissue mitochondrial function. Sci Rep 10:3785. - »Bioblast link«

• Mar-09 Mo

Protein-specific mitochondrial respiratory capacity is higher in women than men from the O2k-Network »SE Stockholm Cardinale DA« Cardinale DA, Larsen FJ, Schiffer TA, Morales-Alamo D, Ekblom B, Calbet JAL, Holmberg HC, Boushel R (2018) Superior intrinsic mitochondrial respiration in women than in men. Front Physiol 9:1133. - »Bioblast link«

• Mar-04 We

Systemic mitochondrial bioenergetics in older adults - skeletal muscle and platelets from the O2k-Network »US FL Orlando Goodpaster BH« Braganza A, Corey CG, Santanasto AJ, Distefano G, Coen PM, Glynn NW, Nouraie SM, Goodpaster BH, Newman AB, Shiva S (2019) Platelet bioenergetics correlate with muscle energetics and are altered in older adults. JCI Insight 5:128248. - »Bioblast link«

• Mar-03 Tu

Rapamycin suppresses senescence in galactose versus glucose cell culture from the O2k-Network »US PA Philadelphia Orynbayeva Z« Nacarelli T, Azar A, Altinok O, Orynbayeva Z, Sell C (2018) Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts. Geroscience 40:243-56. - »Bioblast link«

• Mar-02 Mo

Salty diet, cardiac hypertrophy, calcium overload, and mitochondrial dysfunction from the O2k-Network »CN Chongqing Zhu Z« Lu Z, Cui Y, Wei X, Gao P, Zhang H, Wei X, Li Q, Sun F, Yan Z, Zheng H, Yang G, Liu D, Zhu Z (2018) Deficiency of PKD2L1 (TRPP3) exacerbates pathological cardiac hypertrophy by augmenting NCX1-mediated mitochondrial calcium overload. Cell Rep 24:1639-52. - »Bioblast link«

Feb 2020

• Mar-02 Mo

Salty diet, cardiac hypertrophy, calcium overload, and mitochondrial dysfunction from the O2k-Network »CN Chongqing Zhu Z« Lu Z, Cui Y, Wei X, Gao P, Zhang H, Wei X, Li Q, Sun F, Yan Z, Zheng H, Yang G, Liu D, Zhu Z (2018) Deficiency of PKD2L1 (TRPP3) exacerbates pathological cardiac hypertrophy by augmenting NCX1-mediated mitochondrial calcium overload. Cell Rep 24:1639-52. - »Bioblast link«

• Feb-26 We

It is essential to titrate uncouplers in multiple steps for respirometric measurement of electron transfer capacity. - »Noncoupled respiration«

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• Feb-24 Mo

More research is needed on the impact of viral infection on mitochondrial function. - »Viruses and mitochondrial medicine«

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• Feb-19 We

Spermidine and other calorie restriction mimetics control autophagy and mitochondrial function. - »Spermidine«

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• Feb-18 Tu

Why do we fight gas bubbles? - Dive deep into »Oxygen solubility«

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• Feb-12 We

What do metformin, melatonin and other bioactive mitObesity compounds have in common? - »MitObesity drugs«

Jan 2020

• Jan-16 Th

Oxygen flux - which SI units should be used?

Did you ever think that units for body mass could be an issue? - »Body mass«

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• Jan-08 We

Force and Energy: this we all need in the New Year - and MitoPedia may help to clarify the difference.