Semantic search
Year | Reference | Coupling | Pathways | Preparations | Species;model | Tissue;cell | |
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Keeney 2009 Hum Gene Ther | 2009 | Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett JP (2009) Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model. Hum Gene Ther 20:897-907. | OXPHOS LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system Neuroblastoma |
Hoeks 2008 FEBS Lett | 2008 | Hoeks J, Briedé JJ, de Vogel J, Schaart G, Nabben M, Moonen-Kornips E, Hesselink MK, Schrauwen P (2008) Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high-fat feeding. FEBS Lett 582:510-16. | ROUTINE OXPHOS ET | F NS ROX | Isolated mitochondria | Rat | Skeletal muscle |
Spacek 2008 Int J Biochem Cell Biol | 2008 | Spacek T, Santorová J, Zacharovová K, Berková Z, Hlavatá L, Saudek F, Jezek P (2008) Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential. Int J Biochem Cell Biol 40:1522-35. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Islet cell;pancreas;thymus Other cell lines |
Gnaiger 2008 POS | 2008 | Gnaiger E (2008) Polarographic oxygen sensors, the oxygraph and high-resolution respirometry to assess mitochondrial function. In: Mitochondrial dysfunction in drug-induced toxicity (Dykens JA, Will Y, eds) John Wiley & Sons, Inc, Hoboken, NJ:327-52. | LEAK ROUTINE ET | ROX | Permeabilized cells Permeabilized tissue Intact cells | Mouse | Blood cells |
Franciso 2007 Eur J Pharmacol | 2007 | Franciso R, Perez-Tomas R, Gimenez-Bonafe P, Soto-Cerrato V, Gimenez-Xavier P, Santiago A (2007) Mechanisms of prodigiosin cytotoxicity in human neuroblastoma cell lines. Eur J Pharmacol 572:111-9. | ROUTINE | Intact cells | Human | Neuroblastoma | |
Rodriguez-Juarez 2007 Biochem J | 2007 | Rodriguez-Juarez F, Aguirre E, Cadenas S (2007) Relative sensitivity of soluble guanylate cyclase and mitochondrial respiration to endogenous nitric oxide at physiological oxygen concentration. Biochem J 405:223-31. | ROUTINE | Intact cells | Rat | Fibroblast | |
Cadenas 2006 Biochim Biophys Acta | 2006 | Aguirre E, Rodriguez-Juarez F, Gnaiger E, Cadenas S (2006) Measurement of the control of cellular respiration by nitric oxide under normoxia and hypoxia: instrumental comparison including high-resolution respirometry. Biochim Biophys Acta, EBEC Short Reports Suppl 14:136-7. | ROUTINE | Enzyme Oxidase;biochemical oxidation Intact cells | Human | HEK | |
Huetter 2006 Exp Gerontol | 2006 | Hütter E, Unterluggauer H, Garedew A, Jansen-Dürr P, Gnaiger E (2006) High-resolution respirometry - a modern tool in aging research. Exp Gerontol 41:103-9. | ROUTINE | Intact cells | Human | Endothelial;epithelial;mesothelial cell HUVEC | |
Stadlmann 2006 Cell Biochem Biophys | 2006 | Stadlmann S, Renner K, Pollheimer J, Moser PL, Zeimet AG, Offner FA, Gnaiger E (2006) Preserved coupling of oxidative phosphorylation but decreased mitochondrial respiratory capacity in IL-1ß treated human peritoneal mesothelial cells. Cell Biochem Biophys 44:179-86. | ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
Hervouet 2006 Biochem Biophys Res Commun | 2006 | Hervouet E, Pecina P, Demont J, Vojtíšková A, Simonnet H, Houštek J, Godinot C (2006) Inhibition of cytochrome c oxidase subunit 4 precursor processing by the hypoxia mimic cobalt chloride. Biochem Biophys Res Commun 344:1086-93. | ROUTINE | Intact cells | Human Saccharomyces cerevisiae Fungi | ||
Ter Veld 2006 Pflugers Arch | 2006 | ter Veld F, Nicolay K, Jeneson JA (2006) Increased resistance to fatigue in creatine kinase deficient muscle is not due to improved contractile economy. Pflugers Arch 452:342-8. doi: 10.1007/s00424-005-0041-6 | ROUTINE | Intact organ | Mouse | Skeletal muscle | |
Krumschnabel 2004 Aquat Toxicol | 2004 | Krumschnabel G, Nawaz M (2004) Acute toxicity of hexavalent chromium in isolated teleost hepatocytes. Aquat Toxicol 70:159-167. | ROUTINE | Intact cells | Fishes | Liver | |
Manzl 2004 J Exp Zool A | 2004 | Manzl C, Krumschnabel G, Schwarzbaum PJ, Chabicovsky M, Dallinger R (2004) Intracellular pH regulation in isolated hepatopancreas cells from the Roman snail (Helix pomatia). J Exp Zool A 301:75-84. | ROUTINE | Intact cells | Molluscs | ||
Huetter 2004 Biochem J | 2004 | Hütter E, Renner K, Pfister G, Stöckl P, Jansen-Dürr P, Gnaiger E (2004) Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts. https://doi.org/10.1042/BJ20040095 | LEAK ROUTINE ET | Intact cells | Human | Fibroblast | |
Manzl 2004 Comp Biochem Physiol C Toxicol Pharmacol | 2004 | Manzl C, Krumschnabel G, Schwarzbaum PJ, Dallinger R (2004) Acute toxicity of cadmium and copper in hepatopancreas cells from the Roman snail (Helix pomatia). Comp Biochem Physiol C Toxicol Pharmacol 138:45-52. | ROUTINE | Molluscs | |||
Pecina 2004 Am J Physiol Cell Physiol | 2004 | Pecina P, Gnaiger E, Zeman J, Pronicka E, Houstek J (2004) Decreased affinity to oxygen of cytochrome c oxidase in Leigh syndrome caused by SURF1 mutations. Am J Physiol Cell Physiol 287:C1384-8. | ROUTINE | Intact cells | Human | Fibroblast | |
Kalbacova 2003 Cytometry | 2003 | Kalbácová M, Vrbacký M, Drahota Z, Melková Z (2003) Comparison of the effect of mitochondrial inhibitors on mitochondrial membrane potential in two different cell lines using flow cytometry and spectrofluorometry. Cytometry 52A:110-6. | ROUTINE | Intact cells | Other cell lines | ||
Gnaiger 2003 Adv Exp Med Biol | 2003 | Gnaiger E (2003) Oxygen conformance of cellular respiration. A perspective of mitochondrial physiology. https://doi.org/10.1007/978-1-4419-8997-0_4 | ROUTINE OXPHOS | N ROX | Intact cells Permeabilized cells Permeabilized tissue Isolated mitochondria Oxidase;biochemical oxidation | Human Rat | Heart Liver Endothelial;epithelial;mesothelial cell Fibroblast |
Vrbacky 2003 Physiol Res | 2003 | Vrbacký M, Krijt J, Drahota Z, Mĕlková Z (2003) Inhibitory effects of Bcl-2 on mitochondrial respiration. Physiol Res 52:545-54. | ROUTINE OXPHOS ET | N S | Intact cells Permeabilized cells | Human Other mammals | Endothelial;epithelial;mesothelial cell Other cell lines HeLa |
Rissanen 2003 Aquat Toxicol | 2003 | Rissanen E, Krumschnabel G, Nikinmaa M (2003) Dehydroabietic acid, a major component of wood industry effluents, interferes with cellular energetics in rainbow trout hepatocytes. Aquat Toxicol 62:45-53. | ROUTINE | Intact cells | Fishes | Liver | |
Krumschnabel 2003 J Exp Biol | 2003 | Krumschnabel G, Gstir R, Manzl C, Prem C, Pafundo D, Schwarzbaum PJ (2003) Metabolic and ionic responses of trout hepatocytes to anisosmotic exposure. J Exp Biol 206:1799-1808. | ROUTINE | Intact cells | Fishes | Liver | |
Renner 2003 Biochim Biophys Acta | 2003 | Renner K, Amberger A, Konwalinka G, Gnaiger E (2003) Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells. Biochim Biophys Acta 1642:115-23. | ROUTINE ET | Permeabilized cells Enzyme Oxidase;biochemical oxidation Intact cells | Human | Blood cells | |
Stadlmann 2002 Transplantation | 2002 | Stadlmann S, Rieger G, Amberger A, Kuznetsov AV, Margreiter R, Gnaiger E (2002) H2O2-mediated oxidative stress versus cold ischemia-reperfusion: mitochondrial respiratory defects in cultured human endothelial cells. Transplantation 74:1800-3. | LEAK ROUTINE OXPHOS | N S CIV ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Huetter 2002 Mol Biol Rep | 2002 | Hütter E, Renner K, Jansen-Dürr P, Gnaiger E (2002) Biphasic oxygen kinetics of cellular respiration and linear oxygen dependence of antimycin A inhibited oxygen consumption. Mol Biol Rep 29:83-7. | ROUTINE | ROX | Intact cells | Human | Fibroblast |
Renner 2002 Mol Biol Rep | 2002 | Renner K, Kofler R, Gnaiger E (2002) Mitochondrial function in glucocorticoid triggered T-ALL cells with transgenic Bcl-2 expression. Mol Biol Rep 29:97-101. | ROUTINE | Intact cells | Human | Blood cells | |
Steininger 2002 J Antimicrob Chemother | 2002 | Steininger C, Allerberger F, Gnaiger E (2002) Clinical significance of inhibition kinetics in Streptococcus pyogenes in response to penicillin. J Antimicrob Chemother 50:517-23. https://doi.org/10.1093/jac/dkf174 | ROUTINE | Intact cells | Eubacteria | ||
Wieser 2001 Biochem J | 2001 | Wieser W, Krumschnabel G (2001) Hierarchies of ATP-consuming processes: direct compared with indirect measurements, and comparative aspects. Biochem J 355:389-395. | ROUTINE | Intact cells | Human Fishes | Liver | |
Krumschnabel 2001 J Exp Biol | 2001 | Krumschnabel G, Manzl C, Schwarzbaum PJ (2001) Regulation of intracellular pH in anoxia-tolerant and anoxia-intolerant teleost hepatocytes. J Exp Biol 204:3943-3951. | ROUTINE | Intact cells | Fishes | Liver | |
Krumschnabel 2001 Gen Comp Endocrinol | 2001 | Krumschnabel G, Manzl C, Schwarzbaum PJ (2001) Metabolic responses to epinephrine stimulation in goldfish hepatocytes: evidence for the presence of alpha-adrenoceptors. Gen Comp Endocrinol 121:205-213. | ROUTINE | Intact cells | Fishes | Liver | |
Chowdhury 2000 Clin Chim Acta | 2000 | Chowdhury SK, Drahota Z, Floryk D, Calda P, Houstek J (2000) Activities of mitochondrial oxidative phosphorylation enzymes in cultured amniocytes. Clin Chim Acta 298:157-73. | LEAK ROUTINE OXPHOS | N S CIV | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Gnaiger 2000 Transpl Int | 2000 | Gnaiger E, Kuznetsov AV, Rieger G, Amberger A, Fuchs A, Stadlmann S, Eberl T, Margreiter R (2000) Mitochondrial defects by intracellular calcium overload versus endothelial cold ischemia/reperfusion injury. Transpl Int 13:S555-7. | ROUTINE OXPHOS | Permeabilized cells Oxidase;biochemical oxidation Intact cells | Human | Endothelial;epithelial;mesothelial cell HUVEC | |
Steurer 1999 Transplant Proc | 1999 | Steurer W, Stadlmann S, Roberts K, Fischer M, Margreiter R, Gnaiger E (1999) Quality assessment of isolated pancreatic rat islets by high-resolution respirometry. Transplant Proc 31:650. | ROUTINE | Intact cells | Rat | Islet cell;pancreas;thymus | |
Guan 1999 J Biotechnol | 1999 | Guan YH, Kemp RB (1999) Detection of the changing substrate requirements of cultured animal cells by stoichiometric growth equations validated by enthalpy balances. J Biotechnol 69:95-114. | ROUTINE | Intact cells | CHO Macrophage-derived | ||
Krumschnabel 1999 Comp Biochem Physiol C Pharmacol Toxicol Endocrinol | 1999 | Krumschnabel G, Schwarzbaum PJ, Wieser W (1999) Energetics of trout hepatocytes during A23187-induced disruption of Ca2+ homeostasis. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 124:187-195. | ROUTINE | Intact cells | Fishes | Liver | |
Guan 1999 Cytotechnol | 1999 | Guan YH, Kemp RB (1999) On-line heat flux measurements improve the culture medium for the growth and productivity of genetically engineered CHO cells. Cytotechnol 30:107-20. | ROUTINE | Intact cells | CHO | ||
Gnaiger 1998 BTK-HRR | 1998 | Gnaiger E, Kuznetsov AV, Lassnig B, Fuchs A, Reck M, Renner K, Stadlmann S, Rieger G, Margreiter R (1998) High-resolution respirometry. Optimum permeabilization of the cell membrane by digitonin. In BioThermoKinetics in the Post Genomic Era (Larsson C, Pahlman I-L, Gustafsson L, eds) Chalmers Reproservice, Göteborg:89-95. | ROUTINE OXPHOS | S | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell HUVEC |
Gnaiger 1998 J Exp Biol | 1998 | Gnaiger E, Lassnig B, Kuznetsov AV, Rieger G, Margreiter R (1998) Mitochondrial oxygen affinity, respiratory flux control, and excess capacity of cytochrome c oxidase. https://doi.org/10.1242/jeb.201.8.1129 | ROUTINE OXPHOS | N S CIV | Isolated mitochondria Enzyme Oxidase;biochemical oxidation Intact cells | Human Rat | Heart Liver Endothelial;epithelial;mesothelial cell HUVEC |
Kidane 1997 J Thermal Anal | 1997 | Kidane AH, Guan Y, Evans PM, Kaderbhai MA, Kemp RB (1997) Comparison of heat flux in wild-type and genetically-engineered Chinese hamster ovary cells. J Thermal Anal 49: 771-783. | ROUTINE | Intact cells | Other mammals | CHO | |
Krumschnabel 1997 J Comp Physiol B | 1997 | Krumschnabel G, Biasi C, Schwarzbaum PJ, Wieser W (1997) Acute and chronic effects of temperature, and of nutritional state, on ion homeostasis and energy metabolism in teleost hepatocytes. J Comp Physiol B 167:280-6. | ROUTINE | Intact cells | Fishes | Liver | |
Steinlechner-Maran 1997 Transplantation | 1997 | Steinlechner-Maran R, Eberl T, Kunc M, Schröcksnadel H, Margreiter R, Gnaiger E (1997) Respiratory defect as an early event in preservation/reoxygenation injury in endothelial cells. Transplantation 63:136-42. | ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell HUVEC |
Krumschnabel 1996 Am J Physiol | 1996 | Krumschnabel G, Biasi C, Schwarzbaum PJ, Wieser W (1996) Membrane-metabolic coupling and ion homeostasis in anoxia-tolerant and anoxia-intolerant hepatocytes. Am J Physiol 270:R614-620. | ROUTINE | Intact cells | Fishes | ||
Steinlechner-Maran 1996 Am J Physiol Cell Physiol | 1996 | Steinlechner-Maran R, Eberl T, Kunc M, Margreiter R, Gnaiger E (1996) Oxygen dependence of respiration in coupled and uncoupled endothelial cells. Am J Physiol Cell Physiol 271:C2053-61. https://doi.org/10.1152/ajpcell.1996.271.6.C2053 | ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell HUVEC | |
Gnaiger 1995 Springer | 1995 | Gnaiger E (1995) Zelluläre und mitochondriale Adaptationsvorgänge bei Hypoxie. Springer, Berlin, Heidelberg In: Erich Rügheimer (Eds.), Respiratorische Therapie nach operativen Eingriffen:3-16. https://doi.org/10.1007/978-3-642-78399-9_1 | ROUTINE | Human | |||
Gnaiger 1995 J Bioenerg Biomembr | 1995 | Gnaiger E, Steinlechner-Maran R, Méndez G, Eberl T, Margreiter R (1995) Control of mitochondrial and cellular respiration by oxygen. https://doi.org/10.1007/BF02111656 | LEAK ROUTINE OXPHOS | N S | Isolated mitochondria Intact cells | Human Rat | Liver Endothelial;epithelial;mesothelial cell HUVEC |
Kemp 1994 BTK-226 | 1994 | Kemp RB, Hoare S, Schmalfeldt M, Bridge ChMC, Evansa PM, Gnaiger E (1994) A thermochemical study of the producion of lactate by glutaminolysis and glycolysis in mouse macrophage hybridoma cells. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermoKinetics 3. Innsbruck Univ Press:226-31. | ROUTINE | Intact cells | Mouse | Macrophage-derived | |
Krumschnabel 1994 J Exp Biol | 1994 | Krumschnabel G, Malle S, Schwarzbaum PJ, Wieser W (1994) Glycolytic function in goldfish hepatocytes at different temperatures: relevance for Na+ pump activity and protein synthesis. J Exp Biol 193:285-90. | ROUTINE | Intact cells | Fishes | Liver | |
Eberl 1994 BTK-288 | 1994 | Eberl T, Steinlechner R, Salvenmoser W, Abendstein B, Rhomberg M, Schröcksnadel H, Schmid T, Gnaiger E, Margreiter R (1994) Endothelial cell cultures as a model for organ preservation studies. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermoKinetics 3. Innsbruck Univ Press:288-93. | ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell HUVEC | |
Krumschnabel 1994 Physiol Zool | 1994 | Krumschnabel G, Schwarzbaum PJ, Wieser W (1994) Coupling of energy supply and energy demand in isolated goldfish hepatocytes. Physiol Zool 67:438-448. | ROUTINE | Intact cells | Fishes | Liver | |
Knoblechner 1994 BTK-294 | 1994 | Knoblechner A, Steinlechner R, Schirmer M, Gellerich FN, Margreiter R, Konwalinka G, Gnaiger E (1994) The effect of 2-chlorodeoxy-adenosine on endogenous respiration of a human lymphoma cell line (U-937). In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermoKinetics 3. Innsbruck Univ Press:294-6. | ROUTINE | Intact cells | Human | Blood cells | |
SteinlechnerMaran 1994 BTK-283 | 1994 | Steinlechner-Maran R, Eberl T, Margreiter R, Gnaiger E (1994) Oxygen dependence of cellular respiration in endothelial cells: A sensitive toxicological test. In: What is Controlling Life? (Gnaiger E, Gellerich FN, Wyss M, eds) Modern Trends in BioThermo-Kinetics 3. Innsbruck Univ Press:283-7. | ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell HUVEC | |
Krumschnabel 1994 Experientia | 1994 | Krumschnabel G, Wieser W (1994) Inhibition of the sodium pump does not cause a stoichiometric decrease of ATP-production in energy limited fish hepatocytes. Experientia 50:483-5. | ROUTINE | Intact cells | Fishes | Liver | |
Buck 1993 Am J Physiol Regul Integr Comp Physiol | 1993 | Buck LT, Hochachka PW, Schön A, Gnaiger E (1993) Microcalorimetric measurement of reversible metabolic suppression induced by anoxia in isolated hepatocytes. Am J Physiol Regul Integr Comp Physiol 265:R1014-9. | LEAK ROUTINE | Intact cells | Reptiles | Liver | |
Gnaiger 1992 Funct Ecol | 1992 | Gnaiger E (1992) Optimum efficiency of energy transformation and the evolution of catabolic pathways. Funct Ecol 6:234-41. | ROUTINE OXPHOS | Isolated mitochondria | Rat | Liver |