- high-resolution terminology - matching measurements at high-resolution
Succinate and rotenone
Description
Substrate supply by succinate (S) is the basis for electron input through Complex II into the mETS. Inhibition of Complex I by rotenone (Rot; or amytal, piericidine) prevents accumulation of oxaloacetate which is a potent inhibitor of succinate dehydrogenase.
Abbreviation: S(Rot)
Reference: Gnaiger 2012 MitoPathways, MiPNet12.11
MitoPedia topics: Inhibitor, Substrate and metabolite
