Difference between revisions of "Template:Current week ecosystem agenda"

Revision as of 08:58, 4 September 2023

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-» A future for Ukraine is the future of its science

2023 Week 36

Sep- 04 Mo

Sep- 05 Tu

Higher concentrations of oligomycin can decrease the ET capacity due to an inhibitory effect

Use a lower oligomycin concentration (5-10 nM) to measure LEAK respiration without impairing ET capacity and test to find the optimum concentration for your specific model.
- »Oligomycin in high-resolution respirometry«, »Doerrier 2018 Methods Mol Biol«
- communicated by »Timon-Gomez Alba« and »Grings Mateus«

Sep- 06 We

Sep- 07 Th

"...enhancing mitochondrial function by either overexpressing parkin or bypassing defective mitochondrial complexes has significant beneficial effects in a fly model of HD [Huntington's disease], rescuing neurodegeneration and enhancing viability and lifespan."

Campesan S, Del Popolo I, Marcou K, Straatman-Iwanowska A, Repici M, Boytcheva KV, Cotton VE, Allcock N, Rosato E, Kyriacou CP, Giorgini F (2023) Bypassing mitochondrial defects rescues Huntington's phenotypes in Drosophila. »Bioblast link«

from the O2k-Network »UK Leicester Giorgini F«

Sep- 08 Fr

@@ Line 1: / Line 1: @@
 {{Template:Science for Ukraine}}
-Week 35
+Week 36
-*'''Aug- 28 Mo'''
+*'''Sep- 04 Mo'''
-:{|
-| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
-|''' Can I compare data sets recorded with different sensor gain settings? '''<br>
-Oxygen signals obtained after proper calibration are independent of the gain settings, therefore oxygen concentrations (and fluxes) can be compared, as long as the corresponding air and zero calibrations are applied.
-<br>
-- »'''[[Gain#Gain: O2 channel of the O2k|Gain of the O2 channel]]'''«<br>
-- communicated by »[[Baglivo Eleonora]]« and »[[Leo Elettra]]«
-|}
 ----
-*'''Aug- 29 Tu'''
+*'''Sep- 05 Tu'''
 :{|
-| width="100" align="center" |[[File:MitoFit Preprints.png|100px|link=https://wiki.oroboros.at/images/1/19/Arias-Reyes_2023_MitoFit.pdf |MitoFit pdf]]
+| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
-|'''"Altogether, our results show that chronic hypoxia optimizes the efficiency of mitochondrial ATP synthesis in the retrosplenial cortex of mice. Contrastingly, rats sustain the production of ATP only by increasing mitochondrial content and altering mitochondrial dynamics, suggesting drastic mitochondrial malfunctions."'''<br>
+|''' Higher concentrations of oligomycin can decrease the ET capacity due to an inhibitory effect '''<br>
-* Arias-Reyes C, Aliaga-Raduán F, Pinto-Aparicio R, Joseph V, Soliz J (2023) Mitochondrial plasticity in the retrosplenial cortex enhances ATP synthesis during acclimatization to hypoxia in mice but not in rats. MitoFit Preprints 2023.6. https://doi.org/10.26124/mitofit:2023-0006
+Use a lower oligomycin concentration (5-10 nM) to measure LEAK respiration without impairing ET capacity and test to find the optimum concentration for your specific model. <br>
-:from the O2k-Network »[[CA Quebec Soliz J]]«
+- »'''[https://wiki.oroboros.at/index.php/Oligomycin#Application_in_HRR Oligomycin in high-resolution respirometry]'''«, »'''[[Doerrier 2018 Methods Mol Biol]]'''« <br>
+- communicated by »[[Timon-Gomez Alba]]« and »[[Grings Mateus]]«
 |}
 ----
-*'''Aug- 30 We'''
+*'''Sep- 06 We'''
 ----
-*'''Aug- 31 Th'''
+*'''Sep- 07 Th'''
 :{|
 | width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
-|'''"Our study showed that salinity modulates the mitochondrial responses to long-term and acute hypoxia exposure in an euryhaline intertidal bivalve ''C. gigas''."''' <br>
+|'''"...enhancing mitochondrial function by either overexpressing parkin or bypassing defective mitochondrial complexes has significant beneficial effects in a fly model of HD [Huntington's disease], rescuing neurodegeneration and enhancing viability and lifespan."''' <br>
-*Steffen JBM, Sokolov EP, Sokolova IM (2023) Combined effects of salinity and intermittent hypoxia on mitochondrial capacity and reactive oxygen species efflux in the Pacific oyster, ''Crassostrea gigas''  [[Steffen 2023 J Exp Biol|»Bioblast link«]]
+* Campesan S, Del Popolo I, Marcou K, Straatman-Iwanowska A, Repici M, Boytcheva KV, Cotton VE, Allcock N, Rosato E, Kyriacou CP, Giorgini F (2023) Bypassing mitochondrial defects rescues Huntington's phenotypes in ''Drosophila''. [[Campesan 2023 Neurobiol Dis|»Bioblast link«]]
-:from the O2k-Network »[[DE Rostock Sokolova I]]«
+:from the O2k-Network »[[UK Leicester Giorgini F]]«
 |}
 ----
-*'''Sep- 01 Fr'''
+*'''Sep- 08 Fr'''
 ----