Difference between revisions of "ZA Cape Town Ojuka EO"
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|weblink=[http://www.essm.uct.ac.za/ed_ojuka.htm Ojuka E] | |weblink=[http://www.essm.uct.ac.za/ed_ojuka.htm Ojuka E] | ||
|Contact=Ojuka Edward O, O2k-Network Manager South Africa | |Contact=Ojuka Edward O, O2k-Network Manager South Africa | ||
| | |Team previous=Goyaram Veeraj, Imbriolo Jamie, Andrew Brittany, Bezuidenhout Nicole, Feldmann Daneil, George Siddiqah, Kohn Tertius, Leith David, Maarman Gerald, Madlala Hlengiwe, Mendham Amy, Osiki Prisca, Smith James, Webster Christopher, | ||
|Status=[[Power-O2k|''' 2 Power-O2k''']] 2013-2017; '''present:''' [[ZA Cape Town Smith J]] | |||
|Status=[[Power-O2k| '''2 Power-O2k''']] 2013- | |info=[[IOC122]], [[MiPschool Obergurgl 2017| MiPschool 2017]], [[MitoFit Science Camp 2016 Kuehtai AT| MitoFit Science Camp 2016]], [[IOC106]], [[MiPschool_Cape_Town_2015| MiPschool 2015]], [[IOC99]], [[IOC96]], [[MiP2014]], [[IOC90]], [[IOC68]] | ||
|info=[[MiPschool_Cape_Town_2015| | |||
}} | }} | ||
[[Image:MitoFit.jpg|left|60px|link=http://www.mitofit.org/index.php/K-Regio MitoFit|K-Regio MitoFit]] | |||
== MitoFit == | |||
:::: Strategic partner of the [[K-Regio MitoFit]] project. | |||
== O2k-Network Manager == | == O2k-Network Manager == | ||
:: [[George Siddiqah |Siddiqah George, MSc.]] is the ''' | :::: [[George Siddiqah |Siddiqah George, MSc.]] is the '''Oroboros[[O2k-Network Manager South Africa]]'''. | ||
::* [http://www.essm.uct.ac.za/ESSM/News/Siddiqah_George_Oroboros Siddiqah George - newly appointed | ::::* [http://www.essm.uct.ac.za/ESSM/News/Siddiqah_George_Oroboros Siddiqah George - newly appointed Oroboros O2k-Network Manager in South Africa]. Online article by the University of Cape Town: 2015-05-26 | ||
<br/> | |||
== Visiting scientist in the Oroboros O2k-Laboratory == | |||
:::: [[Image:O2k-Network.png|left|40px|link=O2k-Network|O2k-Network]] | |||
[[Bezuidenhout Nicole| Nicole Bezuidenhout]]: Visiting scientist at the [[Oroboros Laboratories: visiting scientists|Oroboros O2k-Laboratory]] from October 05 to November 30 2015. | |||
== "Open day" at the Institute of South Africa Newlands - September 2015 == | |||
<gallery mode=default perrow=2 widths="500px" heights="400px"> | |||
File:Amy Mendham.jpg| [[Mendham A| Amy Mendham]] with a group of eight and ninth graders | |||
File:Hlengiwe Madlala Siddiqah George.jpg| [[George S| Siddiqah George]] and [[Madlala H| Hlengiwe Madlala]] | |||
File:Gerald Maarman.jpg| [[Maarman G| Gerald Maarman]] talking about his experience at the University of Cape Town | |||
File:Powerhouse Body.jpg| The powerhouse of the body | |||
</gallery> | |||
== IOC99 O2k-Workshop 2015-03-23 to 24 == | == IOC99 O2k-Workshop 2015-03-23 to 24 == | ||
::* [[MiPNet20.02 IOC99 | | ::::* [[MiPNet20.02 IOC99 |Oroboros O2k-Workshop on HRR and O2k-Fluorometry, '''IOC99''']], 2015 Mar 23-24. - Satellite to [[MiPschool Cape Town 2015 |7<sup>th</sup> MiP''school'' Cape Town 2015]]. | ||
== Public lecture 2015-03-20, 01:00 pm == | == Public lecture 2015-03-20, 01:00 pm == | ||
: [[Gnaiger E |Erich Gnaiger]] (Austria) '''SCIENCE AND ADVENTURE. The World as a Laboratory: Exploring Mitochondrial Fitness''' | :::: [[Gnaiger E |Erich Gnaiger]] (Austria) '''SCIENCE AND ADVENTURE. The World as a Laboratory: Exploring Mitochondrial Fitness''' | ||
Erich Gnaiger, Professor at the Daniel Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery at the Medical University of Innsbruck, Austria, and CEO of | :::: Erich Gnaiger, Professor at the Daniel Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery at the Medical University of Innsbruck, Austria, and CEO of Oroboros Instruments, will share some of his experiences in the many expeditions he and his team have undertaken to investigate mitochondrial function at extreme conditions: These studies have included (a) analysis of Alaskan huskies before and after the '''1,100 miles long Iditarod race''', b) OXPHOS analysis and acclimation of muscle mitochondria at the Everest base camp located '''5,364 m above sea level''', c) evaluation of mitochondrial fitness in permeabilized muscle fibers obtained from traditional lifestyle '''Inuit hunters in Northern Greenland''' compared to Western lifestyle Inuits and Danish participants of the 42-days expedition. | ||
Erich Gnaiger, who is the president of the Mitochondrial Physiology Society, will be a guest of the University of Cape Town from March 20th – 27th to conduct an '''O2k-Workshop on high-resolution respirometry''' using the | :::: Erich Gnaiger, who is the president of the Mitochondrial Physiology Society, will be a guest of the University of Cape Town from March 20th – 27th to conduct an '''O2k-Workshop on high-resolution respirometry''' using the Oroboros Oxygraph-2k and speak at the '''Mitochondrial Physiology School''' organized by Associate Professor Edward Ojuka of the Exercise Science and Sports medicine research group. | ||
* Johansen K (1987) The August Krogh Lecture: The world as a laboratory. Physiological insights from nature's experiments. In: Advances in physiological research (McLennan H, Ledsome JR, McIntosh CHS, Jones DR, eds). Plenum Publishing Corporation:377-96. »[[Johansen 1987 World as a laboratory |Bioblast Access]]« | ::::* Johansen K (1987) The August Krogh Lecture: The world as a laboratory. Physiological insights from nature's experiments. In: Advances in physiological research (McLennan H, Ledsome JR, McIntosh CHS, Jones DR, eds). Plenum Publishing Corporation:377-96. »[[Johansen 1987 World as a laboratory |Bioblast Access]]« | ||
* [[Gnaiger 2013 MiP2013-Opening]] | ::::* [[Gnaiger 2013 MiP2013-Opening]] | ||
* [[ | ::::* [[The World as a Laboratory]] | ||
[[Category:Power-O2k]] | |||
Latest revision as of 11:17, 19 November 2019
ZA Cape Town Ojuka EO
| O2k-Network Lab |  Institute of South Africa Newlands ESSM UCT Dept of Human Biology Sports Science University of Cape Town |
|---|---|
| Address | Boundary Road, Newlands, 7700 |
| City | Cape Town |
| State/Prov | |
| Country | South Africa |
| Weblink | Ojuka E |
| Contact | Ojuka Edward O, O2k-Network Manager South Africa |
| Team | |
| Team previous | Goyaram Veeraj, Imbriolo Jamie, Andrew Brittany, Bezuidenhout Nicole, Feldmann Daneil, George Siddiqah, Kohn Tertius, Leith David, Maarman Gerald, Madlala Hlengiwe, Mendham Amy, Osiki Prisca, Smith James, Webster Christopher |
| Status | 2 Power-O2k 2013-2017; present: ZA Cape Town Smith J |
| Oroboros Events | IOC122, MiPschool 2017, MitoFit Science Camp 2016, IOC106, MiPschool 2015, IOC99, IOC96, MiP2014, IOC90, IOC68 |
| Topics |
O2k-Publications
| Published | Reference | |
|---|---|---|
| Driescher 2019 Heliyon | 2019 | Driescher N, Joseph DE, Human VR, Ojuka E, Cour M, Hadebe N, Bester D, Marnewick JL, Lecour S, Lochner A, Essop MF (2019) The impact of sugar-sweetened beverage intake on rat cardiac function. Heliyon 5:e01357. |
| Kriel 2018 Sci Rep | 2018 | Kriel J, Mueller-Nedebock K, Maarman G, Mbizana S, Ojuka E, Klumperman B, Loos B (2018) Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics. Sci Rep 8:10348. |
| Enhancing physiological understanding of exercise and obesity: designing personalised intervention strategies 2017 Stellenbosch ZA | 2017-01-30 | Stellenbosch ZA, 2017 Jan 30-Feb 02. Enhancing physiological understanding of exercise and obesity: designing personalised intervention strategies. |
| Osiki 2016 FASEB J | 2016 | Osiki PO, Ojuka E, Marmaan G (2016) An investigation of the suitability of using octanoylcarnitine together with malate as a substrate combination for assessing Beta-oxidation using High Resolution Respirometry. FASEB J 30: 1015.12 . |
| Ojuka 2016 Am J Physiol Endocrinol Metab | 2016 | Ojuka E, Andrew B, Bezuidenhout N, George S, Maarman G, Madlala HP, Mendham A, Osiki PO (2016) Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates. Am J Physiol Endocrinol Metab 310:E715-23. https://doi.org/10.1152/ajpendo.00475.2015 |
| Maarman 2016 J Appl Physiol (1985) | 2016 | Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C2C12 myotubes. J Appl Physiol (1985) 122:1003-10. |
| MiPNet20.02 IOC99 Cape Town | 2015-03-23 |  |
O2k-Abstracts
| Published | Reference | |
|---|---|---|
| Osiki 2016 Abstract MitoFit Science Camp 2016 | 2016 | Suitability of octanoylcarnitine & malate for assessment of beta oxidation capacity by respirometry in aconitase-inhibited samples. |
| Madlala 2016 Abstract MitoFit Science Camp 2016 | 2016 | Fructose-induced defects in selected mitochondrial enzymes is detected by respirometry using glutamate&malate but not pyruvate&malate substrates. |
| Maarman 2016 Abstract MitoFit Science Camp 2016 | 2016 | Melatonin rescues uric acid-induced impairment of respiration in myotubes. |
| Bezuidenhout 2016a Abstract MitoFit Science Camp 2016 | 2016 | Comparison of oxygen dependence of respiration in permeabilized mouse skeletal muscle fibers in two respiration media, MiR06Cr and Buffer Z containing Ctl, Cr and Blebbistatin. |
| George 2015 Abstract MiPschool Cape Town 2015 | 2015 | Regulation of LCAD and SIRT3 activities by NAD+ in skeletal muscle of fructose-fed rats. |
| Madlala 2015 Abstract MiPschool Cape Town 2015 | 2015 | Fructose-induced ROS production: The role of uric acid and transforming growth factor (TGF)-β1. |
| Ojuka 2015 Abstract MiPschool Cape Town 2015 | 2015 | Use of malate or carnitine as co-substrates for assessment of fatty acid oxidation. |
| Bezuidenhout 2015 Abstract MiPschool Cape Town 2015 | 2015 | A study of the effects of fructose feeding & exercise on SIRT 3 regulation in skeletal muscle. |
MitoFit
- Strategic partner of the K-Regio MitoFit project.
O2k-Network Manager
- Siddiqah George, MSc. is the OroborosO2k-Network Manager South Africa.
- Siddiqah George - newly appointed Oroboros O2k-Network Manager in South Africa. Online article by the University of Cape Town: 2015-05-26
- Siddiqah George, MSc. is the OroborosO2k-Network Manager South Africa.
Visiting scientist in the Oroboros O2k-Laboratory
Nicole Bezuidenhout: Visiting scientist at the Oroboros O2k-Laboratory from October 05 to November 30 2015.
"Open day" at the Institute of South Africa Newlands - September 2015
Amy Mendham with a group of eight and ninth graders
Gerald Maarman talking about his experience at the University of Cape Town
The powerhouse of the body
IOC99 O2k-Workshop 2015-03-23 to 24
- Oroboros O2k-Workshop on HRR and O2k-Fluorometry, IOC99, 2015 Mar 23-24. - Satellite to 7th MiPschool Cape Town 2015.
Public lecture 2015-03-20, 01:00 pm
- Erich Gnaiger (Austria) SCIENCE AND ADVENTURE. The World as a Laboratory: Exploring Mitochondrial Fitness
- Erich Gnaiger, Professor at the Daniel Swarovski Research Laboratory, Department of Visceral, Transplant and Thoracic Surgery at the Medical University of Innsbruck, Austria, and CEO of Oroboros Instruments, will share some of his experiences in the many expeditions he and his team have undertaken to investigate mitochondrial function at extreme conditions: These studies have included (a) analysis of Alaskan huskies before and after the 1,100 miles long Iditarod race, b) OXPHOS analysis and acclimation of muscle mitochondria at the Everest base camp located 5,364 m above sea level, c) evaluation of mitochondrial fitness in permeabilized muscle fibers obtained from traditional lifestyle Inuit hunters in Northern Greenland compared to Western lifestyle Inuits and Danish participants of the 42-days expedition.
- Erich Gnaiger, who is the president of the Mitochondrial Physiology Society, will be a guest of the University of Cape Town from March 20th – 27th to conduct an O2k-Workshop on high-resolution respirometry using the Oroboros Oxygraph-2k and speak at the Mitochondrial Physiology School organized by Associate Professor Edward Ojuka of the Exercise Science and Sports medicine research group.
- Johansen K (1987) The August Krogh Lecture: The world as a laboratory. Physiological insights from nature's experiments. In: Advances in physiological research (McLennan H, Ledsome JR, McIntosh CHS, Jones DR, eds). Plenum Publishing Corporation:377-96. »Bioblast Access«
- Gnaiger 2013 MiP2013-Opening
- The World as a Laboratory
- Erich Gnaiger, who is the president of the Mitochondrial Physiology Society, will be a guest of the University of Cape Town from March 20th – 27th to conduct an O2k-Workshop on high-resolution respirometry using the Oroboros Oxygraph-2k and speak at the Mitochondrial Physiology School organized by Associate Professor Edward Ojuka of the Exercise Science and Sports medicine research group.
