MiPschool Obergurgl 2017

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MiPschool Obergurgl 2017

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COST Action MitoEAGLE
MiPsociety

Obergurgl AT, 2017 Jul 23-30. 10th MiPschool 2017 MitoEAGLE and MitoEAGLE Workshop WG1-4.

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Mitochondrial Physiology Society (2017-07-23) MitoGlobal

Abstract: 2017 Jul 23-30, Obergurgl, AT.
MiPschool Obergurgl 2017 group photo.jpg

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2017, ORO, MitoFit, MitoEAGLE, MiP, TRACT, MitoGlobal 




News
Medical University Innsbruck
University of Innsbruck
DK Ageing and Regeneration
TRACT logo.png

Joint terminology review: open for contributions and feedback


Date, venue, organization

  • 2017 July 23-30

Minutes MitoAGLE Obergurgl 2017

Click to open pdf file - Minutes prepared by Zuzana Sumbalova.
Find the WG summaries in the Minutes and also here

Feedback

  • Congratulations on a very successful MiPschool in Obergurgl. The organization was excellent. I'm very happy that I could participate in this event. It has been an amazing time, full of great presentations and exciting discussions. I have learned a lot and I think it will bring benefits in my future work. So one more time, great thanks to you and your team. - Karolina Siewiera, Lodz, PL
  • It was really a pleasure to be a part of such a great group of people and it gave me a motivation in my work. I enjoyed all presentations which were very interesting and brought new insight into the problematics but especially like the small table sessions with experts. Next thing that I will remember for a long time was working with you and Chuck and Javier and everybody else who participated on writing the common review on mitochondrial terminology. I have never seen such a professionality and group spirit during the manuscript preparation and I like it a lot. Those moments were very fascinating and completely absorbing. - Ondrej Sobotka, Hradec Kralova, CZ
  • It was another enjoyable and productive meeting. I am delighted to be a part of this team. My new students have returned from MIPSchool energized and motivated to work on their projects. - Anthony Molina, Winston-Salem, North Carolina, US.
  • The 10th MiPschool and the MitoEAGLE workshop in Obergurgl were an amazingly enriching experience for me. Having just recently started working in mitochondrial physiology, these meetings provided critical insight of what are the state-of-the-art techniques and questions related to mitochondria. The program is balanced, although there is certainly space for improvement. And that is a positive thing. I would also like to emphasize that the sense of scientific community built on sharing knowledge and sheer friendship that allowed me to set new, hopefully long and fruitful collaborations. - Luís Crisóstomo, MSc, PhD Student, Porto, PT.
  • Thanks a lot, has been an amazing meeting. I have learnt a lot and I have enjoyed each minute spent in the beautiful Obergurgl. Also, working with you (Erich Gnaiger) and with Charles (Hoppel) has been an amazing opportunity to learn and grow as a scientist. - Javier Iglesias-González, PhD, Manchester, UK.
  • I just wanted to congratulate and thank you for the exciting and productive MitoEAGLE event. - Brian Irving, PhD, Baton Rouge, La, US
  • I would just like to say thank you for the effort and expertise that you brought in this MiP School. I have learned so much from your training that will assist me in my workplace. Thank you very much for your presentation in Oxygraph. For me, it stands out as one of the best training school I have been to. I have come away with much more knowledge and feel far more equipped to deal with related to mitochondrial research issues. It was lovely to meet you and all the other participants within such a great learning environment. Thank you again such an informative and entertaining days of learning. Now, I am able to walk with a new understanding of and strategies in, dealing in research. - Vipin Sharma, Ahemdabad, IN
  • Thank you once again for a wonderful meeting! Although I was a bit unwell during portions of the meeting, I enjoyed all the discussions and camaraderie. I have attached some pictures that Raj and I captured during the meeting. We also look forward to many photos/videos taken during the meeting as well. Hope to see you all soon. - Shilpa Iyer, Fayetteville , AR, US
  • I am very grateful for having an opportunity to be present at 10th MiPschool and the MitoEAGLE workshop in Obergurgl. For me as a beginner it was great chance to learn a lot about mitochondrial topic, especially those terminology sessions were very enriching. Last but not least, I have met a lot of wonderful people, who are inspiriting and I was my greatest pleasure to spend this time with them. Thank you very much. - Katerina Nozickova, Hradec Kralove, CZ


Programme MiPschool

Bioblast pdf

  • The MiPschool will focus on basic concepts on mitochondrial respiratory states and applications of substrate-uncoupler-inhibitor titration (SUIT) protocols. - Last update: 2017-07-22
        • 2017-07-23
Arrival MiPschool
16:00 Registration
18:30 Joint dinner
20:30 - 21:30 Welcome by the organizers Verena Laner - General Secretary MiPsociety and Erich Gnaiger - Chair COST Action MitoEAGLE
        • 2017-07-24
Session A (morning) Coupling and pathway control in oxidative phosphorylation
08:30-09:10
  • Elemental steps towards understanding mitochondrial core energy metabolism: coupling control (Erich Gnaiger, Medical University of Innsbruck, AT).
09:10-09:40
  • Biochemical coupling efficiency and ATP/O2 ratios (Charles L Hoppel, Case Western Reserve University School of Medicine, Ohio, US).
09:40-10:00 Selected oral presentations A.1-2
10:00-10:30 Coffee/tea break - poster viewing
10:30-11:10
  • The electron transfer-pathway – Q redox regulation and mitochondrial pathways to oxygen (Anthony L Moore, University of Sussex, UK).
11:10-11:40
  • Respiratory pathway control in mitochondrial core energy metabolism: from bioenergetics to mitochondrial physiology (Gnaiger Erich, Medical University of Innsbruck, AT).
11:40-12:00 Selected oral presentations A.3-4
 PresentationSession
Hellgren 2017 MiPschool Obergurgl
Kim Hellgren IMG 4885.JPG
Effect of prenatal hypoxia on adult mitochondrial respiration and ROS production.
A1
Oral
Hoppel 2017 MiPschool Obergurgl A
Charles Hoppel
Biochemical coupling efficiency and ATP/O2 ratios.
A1
Review
Sobotka 2017 MiPschool Obergurgl
Ondrej Sobotka
Reference protocols for ROS production measurements.
A1
Oral
Komlodi 2017 MiPschool Obergurgl
Timea Komlodi
Electron pressure exerted by convergent succinate- and glycerophosphate-pathways to the Q-junction regulate reversed electron transfer to Complex I and H2O2 production.
A1
Oral
Gnaiger 2017 MiPschool A1
Gnaiger Erich.jpg
Elemental steps towards understanding mitochondrial core energy metabolism: coupling control.
A1
Review
Gnaiger 2017 MiPschool A4
Gnaiger Erich.jpg
Respiratory pathway control in mitochondrial core energy metabolism: from bioenergetics to mitochondrial physiology.
A1
Review
Meszaros 2017 MiPschool Obergurgl
Andras Meszaros
(Very) High-resolution respirometry – a deep dive into oxygen dependence of mitochondrial respiration.
A1
Oral
Moore 2017 MiPschool Obergurgl
Anthony Moore
The electron transfer-pathway – Q redox regulation and mitochondrial pathways to oxygen.
A1
Review
13:00-15:00 Walk&Talk, Run&Fun, Person-to-person poster talks or MIGHT!TM game time
Session B (afternoon) selected abstracts/posters
  • B1: ROS signaling, oxidative stress, cancer
15:00-15:20 Selected oral presentations B1.1-2
15:20-16:00 Poster session and general discussion
16:00-16:30 Coffee/tea - Poster session continued
 PresentationSession
Silkuniene 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Mitochondrial glutamate dehydrogenase activity changes in response to hyperthermic treatment.
B1
Oral
Karavyraki 2017 MiPschool Obergurgl
KaravyrakiMarilena.jpg
Mitochondrial function and morphology linked to metabolic differences in normal, dysplastic and cancerous oral cells.
B1
Gasparrini 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Anti-inflammatory effects of strawberry and honey extracts in RAW 264.7 macrophages stressed with LPS.
B1
Poster
Hoel 2017 MiPschool Obergurgl
Hoel Fredrik
A study on mitochondrial stress responses due to OXPHOS inhibition.
B1
Giampieri 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Strawberry extract protects human dermal fibroblasts against oxidative stress and improves mitochondrial functionality.
B1
Poster
Afrin 2017 MiPschool Obergurgl
AfrinS.jpg
Induction of mitochondrial dysfunction by Manuka honey as a strategy for prevention of colon cancer in vitro model: a rising role on reactive oxygen species, apoptosis, and cell metabolism.
B1
Poster
Brown 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Peroxisomes; underappreciated sources, including post glucose depletion but prior to ketosis, of mitochondrial energy substrates; medium fats and ACoA? Polyunsaturated fats being preferred peroxisomal substrates; energetic implications of Omega 3:6 imbalances, including for the brain.
B1
Oral
Gainutdinov 2017 MiPschool Obergurgl
COST Action MITOEAGLE
Different ways of reactive oxygen species (ROS) formation by brain mitochondria.
B1
Poster
Iglesias-Gonzalez 2017 MiPschool Obergurgl
Javier Iglesias-Gonzalez
Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control.
B1
  • B2: Life style, degenerative and mitochondrial diseases
16:30-17:30 Selected oral presentations B2.1-6
17:30-18:30 Poster session and general discussion
 PresentationSession
Collins 2017 MiPschool Obergurgl
COST Action MitoEAGLE
The effects of a Mediterranean versus Western diet on nonhuman primate skeletal muscle bioenergetics.
B2
Oral
Krylova 2017 MiPschool Obergurgl
KrylovaT.jpg
High-resolution respirometry in diagnostic of mitochondrial complex I deficiency.
B2
Poster
Ene 2017 MiPschool Obergurgl
Hila picture.jpg
Isolated mitochondria transfer restores schizophrenia related deficits in-vitro and in-vivo.
B2
Oral
Crisostomo 2017 MiPschool Obergurgl
CrisostomoL.JPG
Glycerol metabolism in testicular cells – a mitochondrial tale that may control male reproductive potential.
B2
Poster
Isola 2017 MiPschool Obergurgl
Isola Raffa recente piccola.jpg
Do mitochondria counteract diabetes impairment by means of morphological and physiological strategies?
B2
Oral
Pavlovic 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria.
B2
Sharma 2017 MiPschool Obergurgl
Vipin Sharma
Role of ATP-sensitive potassium (KATP) and maxi potassium (BKCa) channels in beta3-adrenoceptors mediated tocolytic effect and involvement of associated mitochondrial calcium dynamics pathways in buffaloes (Bubalus bubalis).
B2
Poster
Soares 2017 MiPschool Obergurgl
Soares Rogerio
Oxidative metabolism during hyperglycemia in individuals with obesity assessed by near infrared spectroscopy.
B2
Oral
Amick 2017 MiPschool Obergurgl
Amick picture.jpg
Bioenergetic profiling of mitochondria isolated from three distinct brain regions relevant to AD pathology in non-human primates.
Oral
B2
Distefano 2017 MiPschool Obergurgl
Giovanna Distefano
Effects of calorie restriction-induced weight loss and exercise on skeletal muscle mitochondrial energetics of older obese subjects.
B2
Oral
18:30 Dinner


        • 2017-07-25
Session C (morning) OXPHOS protocols and data reporting
08:30-09:10
  • Apparent Complex IV excess capacity and biochemical thresholds (Gnaiger Erich, Medical University of Innsbruck, AT).
09:10-09:40
  • Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles (Carolina Doerrier, Oroboros Instruments, AT).
09:40-10:00 Selected oral presentations C.1-2
10:00-10:30 Coffee/tea break - poster viewing
10:30-11:10
  • Respiratory control ratios and control factors (Gnaiger Erich, Medical University of Innsbruck, AT).
11:10-11:40
  • Discussion: Normalization of respiratory flux and flow.
11:40-11:50 Selected oral presentations C.3-4
 PresentationSession
Garcia-Souza 2017 MiPschool Obergurgl
Luiz Garcia-Souza
Assessment of mitochondrial respiratory function in cryopreserved platelets.
C1
Oral
Keppner 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Different respiratory states to determine LEAK and uncoupled respiration in the SUIT protocol: effect and consequences.
C1
Oral
Siewiera 2017 MiPschool Obergurgl
Karolina Siewiera
Blood platelets as bioenergetic markers of brain damage in STZ-diabetes.
C1
Oral
Gnaiger 2017 MiPschool C1
Gnaiger Erich.jpg
Apparent Complex IV excess capacity and biochemical thresholds.
Review
C1
Doerrier 2017 MiPschool C2
DoerrierC.JPG
Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles.
C1
Review
Nogueras 2017 MiPschool Obergurgl
Lara Nogueras.jpg
Mitochondrial dysfunction in peripheral blood mononuclear cells from multiple sclerosis patients.
C1
Oral
Gnaiger 2017 MiPschool C4
Gnaiger Erich.jpg
Respiratory control ratios and control factors
Review
C1
13:00-15:00 Walk & Talks, Run & Fun, Person-to-person poster talks or MIGHT!TM game time
Session D (afternoon) Posters and selected abstracts
  • D1. Models and mt-preparations in mitochondrial physiology
15:00-16:00 Selected oral presentations D1.1-6
16:00-16:30 Coffee/tea - poster viewing
 PresentationSession
Markova 2017 MiPschool Obergurgl
Michaela Markova
Mitochondrial respiration in the rat left heart ventricle after inhibition of pyruvate dehydrogenase kinase.
D1
Oral
Krajcova 2017 MiPschool Obergurgl
Krajcova A
Developing a method of assessing mitochondrial functions in homogenates of human heart muscle.
D1
McKenna 2017 MiPschool Obergurgl
COST Action MitoEAGLE
A systematic review of the use of respirometry in critically ill patients.
D1
Oral
Rao 2017 MiPSchool Obergurgl
COST Action MITOEAGLE
Coauthor of Iyer 2017b MiPschool Obergurgl and Iyer 2017a MiPschool Obergurgl
D1
Juhasz 2017 MiPschool Obergurgl
Juhasz L.jpg
Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats.
D1
Oral
Petit 2017 MiPschool Obergurgl
Michele Petit
Role of oxaloacetate decarboxylase FAHD1 in regulation of cell proliferation and cellular senescence.
Oral
D1
Holzknecht 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Metabolic characterization of Fahd1 knock-out cardiomyocytes in a mammalian model organism - an outlook.
Oral
D1
Iyer 2017b MiPschool Obergurgl
Shilpa Iyer
Patient-specific stem cell models for mitochondrial diseases.
D1
Oral
Bento 2017 MiPschool Obergurgl
Guida Bento Foto.JPG
Isolation of human urine-derived stem cells for mitochondrial function profile assessment.
D1
  • D2. Pharmacological intervention, toxicology, and regulation
16:30-17:10 Selected oral presentations D2.1-4
17:10-18:00 Poster session and general discussion
18:00 Dinner
 PresentationSession
Dias 2017 MiPschool Obergurgl
Dias photo.jpg
Differential effects of epigallocatechin-3-gallate and L-theanine on the proliferation and mitochondrial functionality of human Sertoli cells.
D2
Oral
Liebscher 2017 MiPschool Obergurgl
Gudrun Liebscher
The LAMTOR complex in regulation of fat metabolism.
D2
Oral
Baraldo 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Fahd-1 links metabolism and neuronal activity in C. elegans.
D2
Oral
Forbes-Hernandez 2017 MiPschool Obergurgl
COST Action MitoEAGLE
The reduction of mitochondrial functionality by a strawberry extract: a mechanism that contributes to its lipid-lowering effect?
D2
Poster
Varela-Lopez 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Mitochondrial function impairment after Duxorubicin treatment is attenuated by strawberry intake in old and young rats.
D2
Poster
Ferreira 2017 MiPschool Obergurgl
Ferreira Luciana
Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes.
D2
Bernardino 2017 MiPschool Obergurgl
Raquel Bernardino.JPG
Mitochondrial biogenesis and morphological alterations in human Sertoli cells after carbonic anydrase inhibition.
D2
Oral
Reboredo-Rodriguez 2017 MiPschool Obergurgl
Reboredo-Rodriguez Patricia
Protective effect of a polyphenol-rich strawberry extract on oxidative and endoplasmic reticulum stresses in HepG2 cell line.
D2
Poster
20:00-21:30
Session D3 MitoEAGLE Early Career Investigators forum (organized by Komlòdi Timea, Oroboros Instruments, Innsbruck, AT; and Garcia e Souza Luiz, University Innsbruck, AT): Meet the expert


        • 2017-07-26
Session E1 (morning) Clinical mitochondrial physiology
08:30-09:00
  • The challenges of functional mitochondrial diagnosis (Charles L Hoppel, Case Western Reserve University School of Medicine, Ohio, US).
09:00-09:30
  • Mitochondrial fitness in skeletal muscle (Pablo Garcia-Roves, University of Barcelona, ES).
09:30-10:00
  • Scope and limitations of functional mitochondrial diagnosis in blood cells. (Anthony Molina,Department of Internal Medicine, US).
10:00-10:30 Coffee/tea break
10:30-11:00
  • The scope of cryopreservation in blood cells for functional mitochondrial diagnosis. (Beata Cizmarova, Pavol Jozef Šafárik University in Kosice, SK)
11:00-11:30
  • Mitochondrial physiology in plants, alternative oxidases, and clinical perspectives (Anthony L Moore, University of Sussex, UK).
11:30-12:00
  • Pyruvate therapy for mitochondrial diseases (Masashi Tanaka, Tokyo Metropolitan Institute of Gerontology, JP).
 PresentationSession
Garcia-Roves 2017 MiPschool Obergurgl
Garcia-RovesP.jpg
Mitochondrial fitness in skeletal muscle.
E1
Review
Hoppel 2017 MiPschool Obergurgl E1
Charles Hoppel
The challenges of functional mitochondrial diagnosis.
E1
Review
Cizmarova 2017 MiPschool Obergurgl
Beata Cizmarova
The scope of cryopreservation in blood cells for functional mitochondrial diagnosis.
E1
Review
Molina 2017 MiPschool Obergurgl
Anthony Molina
Scope and limitations of functional mitochondrial diagnosis in blood cells.
E1
Moore 2017 MiPschool Obergurgl E1
Anthony Moore
Mitochondrial physiology in plants, alternative oxidases, and clinical perspectives.
E1
Review
Tanaka 2017 MiPschool Obergurgl
TanakaM.jpg
Metabolomic analysis of the effect of heavy water on mitochondrial oxidative phosphorylation.
E1
Review
13:00-15:00 Walk&Talks, Run&Fun, Person-to-person poster talks, MIGHT!TM game time
Session E2 (afternoon) Mitochondrial physiology: biomedical applications
15:00-15:30
  • Mitochondrial function and dysfunction: ROS and Ca2+. (Werner Koopman, Radboud University Nijmegen Medical Centre, NL)
15:30-16:00
  • Mitochondrial function and dysfunction in cancer (Richard K Porter, Trinity College Dublin, IE).
16:00-16:30 Coffee/tea
16:30-17:00
  • The metabolic syndrome - dysmitochondrial syndrome and mitochondrial disruptors (Hong Kyu Lee, Eulji University College of Medicine, Seoul, KR).
17:00-17:30
  • Mitochondrial function in aging and regeneration (Pidder Jansen-Duerr, University of Innsbruck, AT).
 PresentationSession
Jansen-Duerr 2017 MiPschool Obergurgl
Jansen-Duerr P
Role of mitochondria in ageing and regeneration.
E2
Review
Lee 2017 MiPschool Obergurgl
LeeHK.jpg
The metabolic syndrome (MetS) - dysmitochondrial syndrome and mitochondrial disruptors. Lee_Presentation
E2
Review
Porter 2017 MiPschool Obergurgl
Richard Porter
Mitochondrial function and dysfunction in cancer.
E2
Koopman 2017 MiPschool Obergurgl
Werner Koopman
Mitochondrial function and dysfunction: ROS detection and redox analysis. Koopman_Presenation
E2
Review


18:30 Dinner
20:00 Conclusion and social programme with Raphael


        • 2017-07-27
Departure MiPschool
Relaxing day for participants staying for the MitoEAGLE WG Workshop


Lecturers



Programme MitoEAGLE Working Groups Workshop

Bioblast pdf

        • 2017-07-27
Arrival MitoEAGLE workshop
        • 2017-07-28 to 29
MitoEAGLE Workshop: WG1-4
  • WG1: Harmonization of nomenclature on mitochondrial respiratory states and control parameters: Status of the consensus paper on a consistent terminology on mitochondrial physiology and bioenergetics; recommendations for the use of a common terminology in mitochondrial physiological research as a milestone towards unification of concepts and nomenclature.
» The protonmotive force and respiratory control: Building blocks of mitochondrial physiology - Manuscript in preparation by the MitoEAGLE Terminology Group.
» Add critical discussion on 'ATP production' (not to be confused with a difference of respiratory fluxes), 'glycolytic flux' (not to be confused with extracellular proton flux), 'reserve capacity' (is the difference of ET capacity and ROUTINE respiratory activity a 'reserve'?), confusion of ET capacity ('State 3u') and OXPHOS capacity, ..
  • WG1: Respirometric reference protocols:
  1. Standard format for presenting substrate-uncoupler-inhibitor titration (SUIT) protocols for a ‘library of protocols’ applied in mitochondrial respiratory physiology.
  2. Criteria for selecting and recommending reference protocols.
  3. Documentation of the state-of-the-art standards in designing, conducting, reporting, interpreting, and validating SUIT protocols.
  4. Compare: Maelstrom Research program- data repository and harmonization.
  • WG2-4: Data repositories
  1. Summary of WG2: steps towards database: Summary from Obergurgl, 2017.
  2. Summary of WG4 cell lines: WG4 Cell Lines Obergurgl, 2017.
  3. Summary of WG4 blood cells:WG4 Blood cells Obergurgl, 2017


        • 2017-07-30
Departure MitoEAGLE
 PresentationMiP areasMammals;modelsTissues;cellsStress conditionsPathological statesSession
Scatena 2017 MITOEAGLE Obergurgl
Roberto Scatena
Cancer stem cell differentiation induced by PPAR ligands. Which role for an inhibition of mitochondrial respiratory chain?
Pharmacology;toxicologyHumanLiverCancerA1
Poster
Dubouchaud 2017 MITOEAGLE Obergurgl
COST Action MitoEAGLE
Effects of a single bout of exercise on the production of reactive oxygen species in muscle and liver isolated mitochondria.
Exercise physiology;nutrition;life style
Respiration
RatSkeletal muscle
Liver
Oxidative stress;RONSA1
Oral
Ukropec 2017 MITOEAGLE Obergurgl
COST Action MitoEAGLE
Could functional state of muscle mitochondria reflect exercise-induced changes in insulin sensitivity, glucose tolerance and cognitive performance in individuals with mild cognitive impairment?
Respiration
Exercise physiology;nutrition;life style
Skeletal muscleAging;senescence
Diabetes
Neurodegenerative
A1
Oral
Crisostomo 2017 MITOEAGLE Obergurgl
CrisostomoL.JPG
Glycerol metabolism in testicular cells – a mitochondrial tale that may control male reproductive potential.
HumanGenitalA1
Oral
Poster
Iglesias-Gonzalez 2017 MITOEAGLE Obergurgl
Javier Iglesias-Gonzalez
Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control.
Respiration
mt-Medicine
Oxidative stress;RONSA1
Oral
Pavlovic 2017 MITOEAGLE Obergurgl
Kasja picture.JPG
Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria.
Respiration
mt-Medicine
mt-Awareness
MouseSkeletal muscleDiabetesA1
Oral
Muntane 2017 MITOEAGLE Obergurgl
Jordi Muntane
Integration of oxidative and nitrosative stress in the overall cell death signaling induced by Sorafenib in hepatoma cells.
Pharmacology;toxicologyHumanLiverCell death
Oxidative stress;RONS
CancerA1
Oral
Chabi 2017 MITOEAGLE Obergurgl
ChabiB.JPG
Optimization of permeabilized fibers preparation for mitochondrial respiration measurements using Design of Experiments methodology.
RespirationMouseSkeletal muscleA1
Poster
Krajcova 2017 MITOEAGLE Obergurgl
Krajcova A
Developing a method of assessing mitochondrial functions in homogenates of human heart muscle.
Respiration
Pharmacology;toxicology
HumanCardiovascularA1
Oral
Gainutdinov 2017 MITOEAGLE Obergurgl
COST Action MitoEAGLE
Different ways of reactive oxygen species (ROS) formation by brain mitochondria.
RespirationMouse
Rat
Nervous systemOxidative stress;RONSA1
Oral
Waldauf 2017 MITOEAGLE Obergurgl
COST Action MitoEAGLE
Effect of propofol on energy metabolism in an in vitro model of human skeletal muscle homogenates.
Respiration
Pharmacology;toxicology
HumanSkeletal muscleA1
Oral
Bento 2017 MITOEAGLE Obergurgl
Guida Bento Foto.JPG
Isolation of human urine-derived stem cells for mitochondrial function profile assessment.
RespirationHumanStem cellsA1
Oral
Garcia-Roves 2017 MITOEAGLE Obergurgl
Pablo Miguel Garcia-Roves
MitoEAGLE data repository on muscle tissues - current status.
A1
Oral
Ferreira 2017 MITOEAGLE Obergurgl
Ferreira Luciana
Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes.
Pharmacology;toxicology
Respiration
MouseHeart
Stem cells
A1
Oral


Participants - alphabetical order

(Attendance list)
 PresentationSession
Afrin 2017 MiPschool Obergurgl
AfrinS.jpg
Induction of mitochondrial dysfunction by Manuka honey as a strategy for prevention of colon cancer in vitro model: a rising role on reactive oxygen species, apoptosis, and cell metabolism.
B1
Poster
Amick 2017 MiPschool Obergurgl
Amick picture.jpg
Bioenergetic profiling of mitochondria isolated from three distinct brain regions relevant to AD pathology in non-human primates.
Oral
B2
Ashcroft 2017 MiPschool Obergurgl
COST Action MITOEAGLE
No abstract.
Baraldo 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Fahd-1 links metabolism and neuronal activity in C. elegans.
D2
Oral
Bekebrede 2017 MiPschool Obergurgl
COST Action MITOEAGLE
No abstract.
Bento 2017 MiPschool Obergurgl
Guida Bento Foto.JPG
Isolation of human urine-derived stem cells for mitochondrial function profile assessment.
D1
Bernardino 2017 MiPschool Obergurgl
Raquel Bernardino.JPG
Mitochondrial biogenesis and morphological alterations in human Sertoli cells after carbonic anydrase inhibition.
D2
Oral
Bezuidenhout 2017 MiPschool Obergurgl
Bezuidenhout N.jpg
No abstract.
Brown 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Peroxisomes; underappreciated sources, including post glucose depletion but prior to ketosis, of mitochondrial energy substrates; medium fats and ACoA? Polyunsaturated fats being preferred peroxisomal substrates; energetic implications of Omega 3:6 imbalances, including for the brain.
B1
Oral
Cizmarova 2017 MiPschool Obergurgl
Beata Cizmarova
The scope of cryopreservation in blood cells for functional mitochondrial diagnosis.
E1
Review
Collins 2017 MiPschool Obergurgl
COST Action MitoEAGLE
The effects of a Mediterranean versus Western diet on nonhuman primate skeletal muscle bioenergetics.
B2
Oral
Crisostomo 2017 MiPschool Obergurgl
CrisostomoL.JPG
Glycerol metabolism in testicular cells – a mitochondrial tale that may control male reproductive potential.
B2
Poster
Di Nolfo 2017 MiPschool Obergurgl
Federica Di Nolfo
Middle cerebral artery modification in mouse model of Marfan Syndrom and potential role of Nox4.
Dias 2017 MiPschool Obergurgl
Dias photo.jpg
Differential effects of epigallocatechin-3-gallate and L-theanine on the proliferation and mitochondrial functionality of human Sertoli cells.
D2
Oral
Distefano 2017 MiPschool Obergurgl
Giovanna Distefano
Effects of calorie restriction-induced weight loss and exercise on skeletal muscle mitochondrial energetics of older obese subjects.
B2
Oral
Doerrier 2017 MiPschool C2
DoerrierC.JPG
Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles.
C1
Review
Ene 2017 MiPschool Obergurgl
Hila picture.jpg
Isolated mitochondria transfer restores schizophrenia related deficits in-vitro and in-vivo.
B2
Oral
Ferreira 2017 MiPschool Obergurgl
Ferreira Luciana
Doxorubicin toxicity and mitochondrial dysfunction in mouse induced pluripotent stem cells-derived cardiomyocytes.
D2
Forbes-Hernandez 2017 MiPschool Obergurgl
COST Action MitoEAGLE
The reduction of mitochondrial functionality by a strawberry extract: a mechanism that contributes to its lipid-lowering effect?
D2
Poster
Gainutdinov 2017 MiPschool Obergurgl
COST Action MITOEAGLE
Different ways of reactive oxygen species (ROS) formation by brain mitochondria.
B1
Poster
Garcia-Roves 2017 MiPschool Obergurgl
Garcia-RovesP.jpg
Mitochondrial fitness in skeletal muscle.
E1
Review
Garcia-Souza 2017 MiPschool Obergurgl
Luiz Garcia-Souza
Assessment of mitochondrial respiratory function in cryopreserved platelets.
C1
Oral
Gasparrini 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Anti-inflammatory effects of strawberry and honey extracts in RAW 264.7 macrophages stressed with LPS.
B1
Poster
Gerna 2017 MiPschool Obergurgl
COST Action MITOEAGLE
No abstract.
Ghanim 2017 MiPschool Obergurgl
Magda Ghanim
HAMLET derivatives as a pre-operative therapy in oesophageal cancer.
Giampieri 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Strawberry extract protects human dermal fibroblasts against oxidative stress and improves mitochondrial functionality.
B1
Poster
Gnaiger 2017 MiPschool A1
Gnaiger Erich.jpg
Elemental steps towards understanding mitochondrial core energy metabolism: coupling control.
A1
Review
Gnaiger 2017 MiPschool A4
Gnaiger Erich.jpg
Respiratory pathway control in mitochondrial core energy metabolism: from bioenergetics to mitochondrial physiology.
A1
Review
Gnaiger 2017 MiPschool C1
Gnaiger Erich.jpg
Apparent Complex IV excess capacity and biochemical thresholds.
Review
C1
Gnaiger 2017 MiPschool C4
Gnaiger Erich.jpg
Respiratory control ratios and control factors
Review
C1
Hellgren 2017 MiPschool Obergurgl
Kim Hellgren IMG 4885.JPG
Effect of prenatal hypoxia on adult mitochondrial respiration and ROS production.
A1
Oral
Hoel 2017 MiPschool Obergurgl
Hoel Fredrik
A study on mitochondrial stress responses due to OXPHOS inhibition.
B1
Holzknecht 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Metabolic characterization of Fahd1 knock-out cardiomyocytes in a mammalian model organism - an outlook.
Oral
D1
Hoppel 2017 MiPschool Obergurgl A
Charles Hoppel
Biochemical coupling efficiency and ATP/O2 ratios.
A1
Review
Hoppel 2017 MiPschool Obergurgl E1
Charles Hoppel
The challenges of functional mitochondrial diagnosis.
E1
Review
Iglesias-Gonzalez 2017 MiPschool Obergurgl
Javier Iglesias-Gonzalez
Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control.
B1
Irving 2017 MiPSchool Obergurgl
Brian Irving
No abstract.
Isola 2017 MiPschool Obergurgl
Isola Raffa recente piccola.jpg
Do mitochondria counteract diabetes impairment by means of morphological and physiological strategies?
B2
Oral
Iyer 2017a MiPschool Obergurgl
Shilpa Iyer
A science-based strategy game for understanding mitochondrial bioenergetics.
Iyer 2017b MiPschool Obergurgl
Shilpa Iyer
Patient-specific stem cell models for mitochondrial diseases.
D1
Oral
Jansen-Duerr 2017 MiPschool Obergurgl
Jansen-Duerr P
Role of mitochondria in ageing and regeneration.
E2
Review
Juhasz 2017 MiPschool Obergurgl
Juhasz L.jpg
Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats.
D1
Oral
Kamel 2017 MiPschool Obergurgl
COST Action MITOEAGLE
No abstract.
Karavyraki 2017 MiPschool Obergurgl
KaravyrakiMarilena.jpg
Mitochondrial function and morphology linked to metabolic differences in normal, dysplastic and cancerous oral cells.
B1
Keppner 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Different respiratory states to determine LEAK and uncoupled respiration in the SUIT protocol: effect and consequences.
C1
Oral
Komlodi 2017 MiPschool Obergurgl
Timea Komlodi
Electron pressure exerted by convergent succinate- and glycerophosphate-pathways to the Q-junction regulate reversed electron transfer to Complex I and H2O2 production.
A1
Oral
Koopman 2017 MiPschool Obergurgl
Werner Koopman
Mitochondrial function and dysfunction: ROS detection and redox analysis. Koopman_Presenation
E2
Review
Krajcova 2017 MiPschool Obergurgl
Krajcova A
Developing a method of assessing mitochondrial functions in homogenates of human heart muscle.
D1
Krylova 2017 MiPschool Obergurgl
KrylovaT.jpg
High-resolution respirometry in diagnostic of mitochondrial complex I deficiency.
B2
Poster
Lee 2017 MiPschool Obergurgl
LeeHK.jpg
The metabolic syndrome (MetS) - dysmitochondrial syndrome and mitochondrial disruptors. Lee_Presentation
E2
Review
Liebscher 2017 MiPschool Obergurgl
Gudrun Liebscher
The LAMTOR complex in regulation of fat metabolism.
D2
Oral
Markova 2017 MiPschool Obergurgl
Michaela Markova
Mitochondrial respiration in the rat left heart ventricle after inhibition of pyruvate dehydrogenase kinase.
D1
Oral
McKenna 2017 MiPschool Obergurgl
COST Action MitoEAGLE
A systematic review of the use of respirometry in critically ill patients.
D1
Oral
Meszaros 2017 MiPschool Obergurgl
Andras Meszaros
(Very) High-resolution respirometry – a deep dive into oxygen dependence of mitochondrial respiration.
A1
Oral
Molina 2017 MiPschool Obergurgl
Anthony Molina
Scope and limitations of functional mitochondrial diagnosis in blood cells.
E1
Moore 2017 MiPschool Obergurgl
Anthony Moore
The electron transfer-pathway – Q redox regulation and mitochondrial pathways to oxygen.
A1
Review
Moore 2017 MiPschool Obergurgl E1
Anthony Moore
Mitochondrial physiology in plants, alternative oxidases, and clinical perspectives.
E1
Review
Nogueras 2017 MiPschool Obergurgl
Lara Nogueras.jpg
Mitochondrial dysfunction in peripheral blood mononuclear cells from multiple sclerosis patients.
C1
Oral
Nozickova 2017 MiPschool Obergurgl
Nozickova K
Sulfite oxidase.
Pavlovic 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria.
B2
Petit 2017 MiPschool Obergurgl
Michele Petit
Role of oxaloacetate decarboxylase FAHD1 in regulation of cell proliferation and cellular senescence.
Oral
D1
Porter 2017 MiPschool Obergurgl
Richard Porter
Mitochondrial function and dysfunction in cancer.
E2
Pranger 2017 MiPschool Obergurgl
COST Action MITOEAGLE
No abstract.
Rao 2017 MiPSchool Obergurgl
COST Action MITOEAGLE
Coauthor of Iyer 2017b MiPschool Obergurgl and Iyer 2017a MiPschool Obergurgl
D1
Reboredo-Rodriguez 2017 MiPschool Obergurgl
Reboredo-Rodriguez Patricia
Protective effect of a polyphenol-rich strawberry extract on oxidative and endoplasmic reticulum stresses in HepG2 cell line.
D2
Poster
Salti 2017 MiPschool Obergurgl
Ahmad Spin pic low.jpg
No abstract.
Schartner 2017 MiPschool Obergurgl
COST Action MITOEAGLE
No abstract.
Schoepp 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Generation and characterization of human cardiomyocytes obtained from iPSCs derived from patients with Friedreich’s ataxia.
Sharma 2017 MiPschool Obergurgl
Vipin Sharma
Role of ATP-sensitive potassium (KATP) and maxi potassium (BKCa) channels in beta3-adrenoceptors mediated tocolytic effect and involvement of associated mitochondrial calcium dynamics pathways in buffaloes (Bubalus bubalis).
B2
Poster
Shi 2017 MiPschool Obergurgl
COST Action MITOEAGLE
No abstract.
Siewiera 2017 MiPschool Obergurgl
Karolina Siewiera
Blood platelets as bioenergetic markers of brain damage in STZ-diabetes.
C1
Oral
Silkuniene 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Mitochondrial glutamate dehydrogenase activity changes in response to hyperthermic treatment.
B1
Oral
Soares 2017 MiPschool Obergurgl
Soares Rogerio
Oxidative metabolism during hyperglycemia in individuals with obesity assessed by near infrared spectroscopy.
B2
Oral
Sobotka 2017 MiPschool Obergurgl
Ondrej Sobotka
Reference protocols for ROS production measurements.
A1
Oral
Stevens 2017 MiPschool Obergurgl
COST Action MITOEAGLE
No abstract.
Tanaka 2017 MiPschool Obergurgl
TanakaM.jpg
Metabolomic analysis of the effect of heavy water on mitochondrial oxidative phosphorylation.
E1
Review
Varela-Lopez 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Mitochondrial function impairment after Duxorubicin treatment is attenuated by strawberry intake in old and young rats.
D2
Poster
Venz 2017 MiPschool Obergurgl
COST Action MITOEAGLE
No abstract.
Waldauf 2017 MiPschool Obergurgl
COST Action MitoEAGLE
Effect of propofol on energy metabolism in an in vitro model of human skeletal muscle homogenates.
Oral
Yuan 2017 MiPschool Obergurgl
Yuan T
No abstract.

Impressions from MiPschool Obergurgl 2017

Sponsors

The project MitoFit is funded by the Land Tirol within the program K-Regio of Standortagentur Tirol.



Medical University Innsbruck K-Regio MitoFit Tourismusverband Ötztal Standortagentur Tirol




Organizers

MiPschool Organizer.jpg



Georg Kandolf - Abstracts
Verena Laner MiPsociety General Secretary - General conference organization
Marija Beno, MitoEAGLE Administrative Representative - General conference organization
Erich Gnaiger, Chair COST Action MitoEAGLE and Chair MiPsociety - Main organizer





10 years ago

» MiPschool Schroecken AT 2007


Support

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This project has received funding from the European Union's Horizon 2020 research and innovation programme supported by COST (European Cooperation in Science and Technology) under grant agreement No OC-2015-2-19984.



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