From Bioblast
US OH Cleveland Hoppel CL
O2k-Network Lab | Case Western Reserve University School of Medicine
Center for Mitochondrial Diseases Center for Inherited Disorders of Energy Metabolism Department of Pharmacology |
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Address | 10900 Euclid Avenue, 44106-4981 |
City | Cleveland |
State/Prov | Ohio (OH) |
Country | USA |
Weblink | |
Contact | Hoppel Charles L |
Team | Golczak Ivona, Hsiao Chao-Pin, Mason Katherine |
Team previous | Ingalls Steve, Lai Nicola, Lemieux Helene |
Status | 2 Power-O2k 2006- |
Oroboros Events | MiPschool 2018, MitoEAGLE 2017 CZ, MiPschool 2017, MitoFit Science Camp 2016, MiPschool Greenville 2015, IOC104, IOC95, MiP2014, MiP2013, MiPschool 2012, IOC91, Bioblast 2012, IOC72, MiP2011, MiP2010, MiPschool 2010, IOC54, IOC47, IOC44, MiPschool 2007, IOC39, IOC35, IOC31, MiP2005 |
Topics |
O2k-Publications
Published | Reference | |
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Axelrod 2021 EMBO Mol Med | 2021 | Axelrod CL, King WT, Davuluri G, Noland RC, Hall J, Hull M, Dantas WS, Zunica ER, Alexopoulos SJ, Hoehn KL, Langohr I, Stadler K, Doyle H, Schmidt E, Nieuwoudt S, Fitzgerald K, Pergola K, Fujioka H, Mey JT, Fealy C, Mulya A, Beyl R, Hoppel CL, Kirwan JP (2021) BAM15-mediated mitochondrial uncoupling protects against obesity and improves glycemic control. EMBO Mol Med 12:12088. |
King 2021 J Biol Chem | 2021 | King WT, Axelrod CL, Zunica ERM, Noland RC, Davuluri G, Fujioka H, Tandler B, Pergola K, Hermann GE, Rogers RC, López-Domènech S, Dantas WS, Stadler K, Hoppel CL, Kirwan JP (2021) Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics. J Biol Chem 297:101196. |
Zunica 2021 Cancer Metab | 2021 | Zunica ERM, Axelrod CL, Cho E, Spielmann G, Davuluri G, Alexopoulos SJ, Beretta M, Hoehn KL, Dantas WS, Stadler K, King WT, Pergola K, Irving BA, Langohr IM, Yang S, Hoppel CL, Gilmore LA, Kirwan JP (2021) Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15. Cancer Metab 9:36. |
Akinbiyi 2021 Sci Rep | 2021 | Akinbiyi EO, Abramowitz LK, Bauer BL, Stoll MSK, Hoppel CL, Hsiao CP, Hanover JA, Mears JA (2021) Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass. Sci Rep 11:22106. |
Kumar 2019 Free Radic Biol Med | 2019 | Kumar A, Davuluri G, Welch N, Kim A, Gangadhariah M, Allawy A, Priyadarshini A, McMullen MR, Sandlers Y, Willard B, Hoppel CL, Nagy LE, Dasarathy S (2019) Oxidative stress mediates ethanol-induced skeletal muscle mitochondrial dysfunction and dysregulated protein synthesis and autophagy. Free Radic Biol Med 145:284-99. |
Hsiao 2018 Anal Biochem | 2018 | Hsiao CP, Hoppel C (2018) Analyzing mitochondrial function in human peripheral blood mononuclear cells. Anal Biochem 549:12-20. |
Chen 2018 Hum Mol Genet | 2018 | Chen A, Tiosano D, Guran T, Baris HN, Bayram Y, Mory A, Shapiro-Kulnane L, Hodges CA, Coban Akdemir Z, Turan S, Jhangiani SN, van den Akker F, Hoppel CL, Salz HK, Lupski JR, Buchner DA (2018) Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency. Hum Mol Genet 27:1913-26. |
Zhou 2017 Biochim Biophys Acta | 2017 | Zhou L, Wang W, Hoppel C, Liu J, Zhu X (2017) Parkinson's disease-associated pathogenic VPS35 mutation causes complex I deficits. Biochim Biophys Acta 1863:2791-5. |
Davuluri 2016 J Physiol | 2016 | Davuluri G, Allawy A, Thapaliya S, Rennison JH, Singh D, Kumar A, Sandlers Y, Van Wagoner DR, Flask CA, Hoppel C, Kasumov T, Dasarathy S (2016) Hyperammonaemia-induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress. J Physiol 594:7341-60. |
Solinas 2014 Mech Ageing Dev | 2014 | Solinas P, Fujioka H, Radivoyevitch T, Tandler B, Hoppel CL (2014) Aging effects on oxidative phosphorylation in rat adrenocortical 3 mitochondria. Mech Ageing Dev 138:10-4. |
Ye 2013 Anal Biochem | 2013 | Ye F, Hoppel CL (2013) Measuring oxidative phosphorylation in human skin fibroblasts. https://doi.org/10.1016/j.ab.2013.02.010 |
Rosca 2011 Biochim Biophys Acta | 2011 | Rosca M, Minkler P, Hoppel CL (2011) Cardiac mitochondria in heart failure: Normal cardiolipin profile and increased threonine phosphorylation of Complex IV. Biochim Biophys Acta 1807:1373-82. |
Ye 2011 J Biol Chem | 2011 | Ye F, Lemieux H, Hoppel CL, Hanson RW, Hakimi P, Croniger CM, Puchowicz M, Anderson VE, Fujioka H, Stavnezer E (2011) Peroxisome proliferator-activated receptor Ξ³ (PPARΞ³) mediates a Ski-induced shift from glycolysis to oxidative energy metabolism. J Biol Chem 286:40013-24. |
Lemieux 2010 J Gerontol A Biol Sci Med Sci | 2010 | Lemieux H, Vazquez EJ, Fujioka H, Hoppel CL (2010) Decrease in mitochondrial function in rat cardiac permeabilized fibers correlates with the aging phenotype. J Gerontol A Biol Sci Med Sci 65:1157-64. |
O2k-Abstracts
Published | Reference | |
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Axelrod 2019 Abstract IOC141 | 2019 | Axelrod CL, Davuluri G, Zunica ERM, Noland RC, Hoppel CL, Kirwan JP (2019) Administration of BAM15 to obese C57BL/6J mice increases skeletal muscle fatty acid oxidation independent of OXPHOS or ETC capacity. Mitochondr Physiol Network 24.02. |
Hoppel 2018 MiPschool Tromso D2 | 2018 | Mitochondrial function during ischemia/reperfusion injury. |
Hoppel 2018 MiPschool Tromso D1 | 2018 | Two populations of muscle mitochondria: heart and skeletal muscle. |
Hoppel 2017 MiP2017 | 2017 | Pathways of mitochondrial fatty acid oxidation. Hoppel_Presentation |
Hoppel 2016b Abstract MitoFit Science Camp 2016 | 2016 | Comparison of permeabilized skeletal muscle fibers or isolated mitochondria for the detection of oxidative phosphorylation defects. |
Hoppel 2016c Abstract MitoFit Science Camp 2016 | 2016 | Mitochondrial respiration in permeabilized skin fibroblasts. |
Hoppel 2012 Abstract Bioblast | 2012 | Hoppel CL (2012) Mitochondrial functional testing β muscle biopsy, isolated mitochondria and others. Mitochondr Physiol Network 17.12. |
Rosca MiP2010 | 2010 | Rosca MG, Hoppel CL (2010) Activation of distinct mitochondrial cAMP-PKA compartments induces different effects on mitochondrial function. |