Difference between revisions of "Coupling-control state"
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Revision as of 17:37, 18 November 2016
Description
Coupling control states are defined in mitochondrial preparations (isolated mitochondria, permeabilized cells, permeabilized tissues, homogenates) as LEAK, OXPHOS, and ETS states of respiration (L, P, E) in any pathway control state which is competent for electron transfer. These coupling states are induced by application of specific inhibitors of the phosphorylation system, titration of ADP and uncouplers. In intact cells, the coupling control states are LEAK, ROUTINE, and ETS states of respiration (L, R, E). Coupling control protocols induce these coupling control states sequentially at a constant pathway control state.
Abbreviation: CCS
Reference: Gnaiger 2009 Int J Biochem Cell Biol
MitoPedia concepts:
MiP concept,
Respiratory state,
SUIT concept,
SUIT state
MitoPedia methods:
Respirometry
MitoPedia topics:
EAGLE
Communicated by Gnaiger E 2011-02-25, edited 2016-10-20.