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NextGen-O2k Dissemination

From Bioblast

Bioblast 2022



NextGen-O2k Dissemination

NextGen-O2k

The revolutionary all-in-one instrument to conquer mitochondrial disease.


WP5: Communication and dissemination



Abstract

Communication and dissemination strategies are in focus. To gain maximum awareness.

Achievements

Project Year 1: One of the first tasks completed for WP5 in year one of the project was the creation of the NextGen-O2k project webpages. We also created and updated a customer-friendly product website. As part of our KOL engagement, we have worked closely with the Q-Module KOLs of the biomedical field to train them and receive feedback on the prototypes. Further strengthening our brand recognition, a communication strategy has been put into place to bring an updated corporate identity with a new look to marketing materials and increased social media presence. In addition to our print and digital presence, the Oroboros Team attended international conferences and hosted O2k-Workshops. To bring awareness to relevant scientific publications in the field, O2k-briefs summarizing key work were published regularly. Finally, in response to COVID-19 we launched a new scientific journal, BEC (Bioenergetics Communications - https://www.bioenergetics-communications.org/).


Project Year 2: In period 2 we continued updating our website and social media as well as monitoring performance via Google Analytics. Marketing materials, such as the NextGen-O2k folder and booth, were finalized and existing materials updated according to the latest corporate identity. To overcome the obstacle of the travel restriction due to COVID-19, we participated in virtual and local events. We furthermore implemented virtual personalized trainings for our customers and key opinion leaders (KOLs). Several scientific and methodological papers were published by our group or in collaboration with KOLs, most of them in the Bioenergetics Communications Journal, launched by us in response to COVID-19.


Progress and next steps

See » Track record

NextGen-O2k dissemination

NextGen-O2k press releases
Oroboros press releases


Oroboros
Press conference for the NextGen-O2k project

On 29th July, Oroboros Instruments hosted a press conference for the NextGen-O2k project. For the development of the NextGen-O2k device, Oroboros Instruments received 1.7 Million Euros from the highly competitive Horizon2020 SME Instrument Phase 2 funding program. Out of 1,848 submissions to the funding scheme, Oroboros was one of 67 companies selected and the first Tyrolian company to receive this type of funding. After the launch of the O2k-FluoRespirometer in 2012, Oroboros's focus on continuous innovation led to the development of the new NextGen-O2k, which extends the analytical and diagnostic power of high-resolution respirometry. The all-in-one MultiSensor instrument for in-depth studies of (1) the mitochondrial role in human diseases, and (2) mitochondria and chloroplasts ability in regulating algal growth as well as metabolite production rates, integrates two new modules: (+1) A Q-Module to measure Q-redox states, and (+2) a PB-Module to study PhotoBiology. The goal of the two-year funded NextGen-O2k project, which started the 1st June 2019, is to finalize the development of the new all-in-one device and prepare its market launch in 2021.


» For more details: NextGen-O2k
First Oroboros Distributor Meeting


NextGen-O2k events

 WhenWhere
MiPNet28.12 IOC164 Schroecken AT2024-09-30
O2k-Workshops.png
Schroecken AT, 2024 Sep 30 - Oct 05. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC164.
MiPNet28.13 IOC165 Innsbruck AT2024-09-02
O2k-Workshops.png
Innsbruck AT, 2024 Sep 02-04. EBEC2024 Satellite Oroboros O2k-Workshop: Mito&Chlora High-Resolution Respirometry and PhotoBiology, IOC165.
MiPNet28.11 IOC163 Schroecken AT2024-06-17
O2k-Workshops.png
Schroecken AT, 2024 Jun 17-22. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC163.
MiPNet28.02 IOC162 Schroecken AT2023-10-02
O2k-Workshops.png
Schroecken AT, 2023 Oct 02-07. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC162.
MiPNet28.01 IOC160 Schroecken AT2023-06-19
O2k-Workshops.png
Schroecken AT, 2023 Jun 19-24. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC160.
MiPNet28.05 IOC158 Innsbruck AT2023-02-27
OROBOROS-solo.png
Innsbruck AT, 2023 Feb 27 - Mar 01. O2k-Coaching Days - Basic, IOC158.
Virtual OroDM022023
NextGenO2k logo.jpg
Virtual Oroboros Distributor Meeting, OroDM02
MiPNet27.04 IOC155 Schroecken AT2022-10-03
O2k-Workshops.png
Schroecken AT, 2022 Oct 03-08. Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC155.
MiPNet27.05 Schroecken BEC tutorial-Living Communications pmP2022-09-30
BEC-logo.png
Schroecken AT, 2022 Sep 30-Oct 03. BEC tutorial-Living Communications: pmF to pmP — pre IOC155.
MiPNet27.03 IOC154 Innsbruck AT2022-08-01
OROBOROS-solo.png
Innsbruck AT, 2022 Aug 01-05. O2k-Coaching Days - O2k-FluoRespirometer and NextGen-O2k, IOC154.
MiPNet27.02 IOC153 Innsbruck AT2022-07-01
NextGenO2k logo.jpg
Innsbruck AT, 2022 Jul 01-02. NextGen-O2k All-in-one Demo Workshop IOC153.
MiPNet 26.16 NextGen-O2k Summit 2021 Virtual2021-10-20
NextGenO2k logo.jpg
Virtual, 2021 Oct 20. NextGen-O2k Summit, NextGen-O2k SME2. MiPNet 26.16.
The 4th Academic Symposium of Metabolic Biology Branch 2021 Guangxi CN2021-07-29Guangxi Province , CN, 2021 Jul 29 - Aug 02. The 4th Academic Symposium of Metabolic Biology Branch of Chinese Biophysical Society.
19th Beijing Conference and Exhibition on Instrumental Analysis 2021 Beijing CN2021-07-27Beijing, CN, 2021 Sep 27-29. 19th Beijing Conference and Exhibition on Instrumental Analysis.
19th Chinese Biophysics congress 2021 Anhui CN2021-07-23Anhui Province , CN, 2021 Jul 23-26. 19th Chinese Biophysics congress.
MiPNet 26.15 NextGen-O2k Event Photobiology: Algal bioenergetics Innsbruck AT2021-07-15
NextGenO2k logo.jpg
Innsbruck AT, 2021 Jul 15-16. NextGen-O2k Event Photobiology: Algal bioenergetics. MiPNet 26.15.
4th China Symposium on Nerve Control Metabolism 2021 Hangzhou city CN2021-06-18Hangzhou city, CN, 2021 Jun 18-19. The 4th China Symposium on Neuro-Controlled Metabolism.
World summit on Diabetes 2021 Virtual2021-06-16Vitual, 2021 Jun 16-17. World Summit on Diabetes: New technologies and practical approaches: Diabetes and Endocrine disorders
ESCI 2021 Virtual2021-06-09
ESCI
Virtual, 2021 Jun 9-11. 55th Annual Scientific Meeting of the European Society for Clinical Investigation, ESCI 2021.
4th edition Metabolism & Cancer 2021 Virtual2021-05-27Virtual, 2021 May 27-29. 4th edition Metabolism & Cancer.
24th Kalorimetrietage 2021 Braunschweig DE2021-05-26Braunschweig, DE, 2021 May 26-28. 24th Kalorimetrietage
ISAP 2021 Virtual2021-05-14Virtual, 2021 May 14-Aug 13. 7th Conference of the International Society for Applied Phycology - ISAP2021.
Career Event - FH Campus 2021 Wien AT2021-01-26Virtual, 2021 Jan 26. Career Event of the FH Campus Wien.
AlgaEurope 2020 Virtual Event2020-12-01
AlgaeEurope.jpg
Rome, IT, 2020 Dec 1-5. AlgaEurope 2020.
2020 PaduaMuscleDays Padua IT2020-11-19Virtual, 2020 Nov 19-21. PaduaMuscleDays - 30 years of translational research
Analytica China 2020 Shanghai CN2020-11-16Shanghai, CN, 2020 Nov 16-18.Analytica China Exhibition - 10th International Trade Fair for Laboratory Technology, Analysis, Biotechnology and Diagnostics.
Long Night of Research 2020 Virtual Event2020-10-09
LNF.JPG
Virtual Event, 2020 Oct 09. Oroboros at Long Night of Research, CCB. The diagnostic bioenergetic report – a milestone on the way to mitochondrial fitness and physical well-being.
12th ÖGMBT Annual Meeting 2020 Virtual Event2020-09-21
ÖGMBT
Virtual Event, 2020 Sep 21-23. 12th ÖGMBT Annual Meeting - Biomolecules in/for 21st century
MitoEAGLE WG2 Innsbruck AT2020-03-09
COST Action MitoEAGLE
Innsbruck AT, 2020 Mar 9-13. WG 2 on human skeletal muscle fibers retreat - COST Action MitoEAGLE.
MitoEAGLE WG4 Innsbruck AT2020-02-26
COST Action MitoEAGLE
Innsbruck AT, 2020 Feb 26-28. WG 4 blood cell workshop and retreat - COST Action MitoEAGLE.
MiPNet25.10 Distributor engagement Tokyo JP2020-02-04
NextGenO2k logo.jpg
Tokyo,JP, 2020 Feb 4-7. On-site O2k-Workshop on High-Resolution Respirometry and partner distribution engagement.
MiPNet25.06 IOC145 Innsbruck AT2020-01-27
OROBOROS-solo.png
Innsbruck AT, 2020 Jan 27-29. O2k-Coaching Days - Basic IOC145.
MiPNet25.03 IOC144 Innsbruck AT2020-01-20
OROBOROS-solo.png
Innsbruck AT, 2020 Jan 20-22. O2k-Coaching Days - Basic IOC144.
1st Myocardial Function Symposium 2020 Graz AT2020-01-10Graz, AT, 2020 Jan 10-11. 1st Myocardial Function Symposium: “Targets in cardiometabolic disease”.
NextGen-O2k SME2 coaching Orily Pratt part 22019-12-03
NextGenO2k logo.jpg
Innsbruck AT, 2019 Dec 03-04 NextGen-O2k SME2 coaching Orily Pratt (part 2), NextGen-O2k SME2.
MiPNet24.15 IOC143 Haryana IN2019-11-15
O2k-Network
Haryana IN, 2019 Nov 15. Oroboros O2k-Workshop on high-resolution respirometry: Assessment of mitochondrial function in health and disease IOC143.
Neurocon 2019 Haryana IN2019-11-15
Neurocon
Haryana, IN. 2019 Nov 15-18, Neurocon 2019.
MiP2019/MitoEAGLE Belgrade RS2019-10-13
COST Action MitoEAGLE
MiPsociety
Belgrade RS, 13-16 Oct 2019. 14th Conference on Mitochondrial Physiology: Mitochondrial function: changes during life cycle and in noncommunicable diseases - COST MitoEAGLE perspectives and MitoEAGLE WG and MC Meeting.
MiPNet24.13 IOC142 Fukuoka JP2019-10-03
O2k-Network
ASMRM & J-mit 2019, Fukuoka JP, 2019 Oct 03 Oroboros Lunch Seminar at ASMRM & J-mit 2019 Fukuoka JP - Explore the Mito-World! (IOC142).
ASMRM & J-mit 2019 Fukuoka JP2019-10-03
ASMRM LOGO.JPG
Fukuoka, JP, 2019 Oct 03-05. Joint ASMRM and J-mit Conference
MiPNet24.02 IOC141 Schroecken AT2019-09-23
NextGenO2k logo.jpg
Schroecken AT, 2019 Sep 23-28 Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC141.
NextGen-O2k SME2 coaching Samia Kappe part 12019-09-12
NextGenO2k logo.jpg
Innsbruck AT, 2019 Sep 10-11 NextGen-O2k SME2 coaching Samia Kappe (part 1), NextGen-O2k SME2.
FEBS Workshop Ageing 2019 Innsbruck AT2019-09-09
FEBS
Innsbruck, AT. 2019 Sep 09-12, FEBS Workshop “Ageing and Regeneration”.
Mitochondrial Physiology ‐ from Organelle to Organism 2019 Copenhagen DK2019-08-19
COST Action MitoEAGLE
Copenhagen DK , 2019 Aug 19-23. Mitochondrial Physiology ‐ from Organelle to Organism
NextGen-O2k SME2 coaching Orily Pratt part 12019-07-22
NextGenO2k logo.jpg
Innsbruck AT, 2019 Jul 22-23 NextGen-O2k SME2 coaching Orily Pratt (part 1), NextGen-O2k SME2.
MiPschool Coimbra 20192019-07-08
COST Action MitoEAGLE
MiPsociety
Coimbra, PT. 2019 Jul 08-11, 12th MiP/MitoEAGLE Training School 2019. Mitochondrial respiratory physiology: Challenges on data sharing, reproducibility, and interpretation.
OroDM01 Innsbruck AT2019-07-01
NextGenO2k logo.jpg
Innsbruck AT, 2019 Jul 01-03 Oroboros Distributor Meeting, OroDM01.
MiPNet24.04 IOC140 Amsterdam NL2019-06-23
O2k-Network
Amsterdam NL, 2019 Jun 23 Pre-conference Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC140.
MiPNet24.01 IOC139 Schroecken AT2019-06-17
O2k-Workshops.png
Schroecken AT, 2019 June 17-22 Oroboros O2k-Workshop on high-resolution respirometry (HRR), IOC139.


NextGen-O2k publications, preprints, and abstracts

LinkReferenceYearView
O2k-Manual
NextGen-O2k: NADH-Module manual
2022-05-17PDF.jpg » Versions
O2k-Manual
DatLab8.0: Cyclic voltammetry manual
2021-10-28Bioblast pdf »Versions
O2k-Manual
NextGen-O2k manual
2022-07-25PDF.jpg » Versions
O2k-Manual
NextGen-O2k: Q-Module manual
2021-10-29PDF.jpg » Versions
O2k-Manual
NextGen-O2k Series XB manual
2023-10-19PDF.jpg » Versions
O2k-Manual
NextGen-O2k: PB-Module manual
2021-10-29PDF.jpg » Versions
Cardoso Luiza HD
Electron transfer from beta-oxidation and TCA cycle and impact of OXPHOS coupling on NADH and coenzyme Q redox states.
Went N, Di Marcello M, Gnaiger E (2021) Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by High-Resolution PhotoRespirometry. MitoFit Preprints 2021.05. https://doi.org/10.26124/mitofit:2021-00052021MitoFit Preprints 2021.05.
MitoFit pdf


Went N (2021) Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by High-Resolution PhotoRespirometry. Batchelor thesis:26 pp.2021Went 2021 Batchelor thesis
Vera-Vives AM, Perin G, Morosinotto T (2022) High-resolution photosynthesis-irradiance curves in microalgae. Bioenerg Commun 2022.19. https://doi.org/10.26124/bec:2022-00192022Bioenerg Commun 2022.19. Open Access pdf
published online 2022-12-15 »Watch the presentation«

Spielmann N, Schenkl C, Komlódi T, da Silva-Buttkus P, Heyne E, Rohde J, Amarie OV, Rathkolb B, Gnaiger E, Doenst T, Fuchs H, Gailus-Durner V, de Angelis MH, Szibor M (2022) Knockout of the Complex III subunit Uqcrh causes bioenergetic impairment and cardiac contractile dysfunction. Mamm Genome 10.1007/s00335-022-09973-w2022Open Access PMID:36565314
Ravasz D, Bui D, Nazarian S, Pallag G, Karnok N, Roberts J, Marzullo BP, Tennant DA, Greenwood B, Kitayev A, Hill C, Komlódi T, Doerrier C, Cunatova K, Fernandez-Vizarra E, Gnaiger E, Kiebish Michael A, Raska A, Kolev K, Czumbel B, Narain NR, Seyfried TN, Chinopoulos C (2024) Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia. Sci Rep 14:1729. https://doi.org/10.1038/s41598-024-51365-42024PMID: 38242919 Open Access
Ravasz D, Bui D, Kitayev A, Greenwood B, Hill C, Komlodi T, Doerrier C, Ozohanics O, Moore AL, Gnaiger E, Kiebish M, Kolev K, Seyfried TN, Willis WT, Narain N, Adam-Vizi V, Chinopoulos C (2019) Endogenous quinones sustain a moderate NADH oxidation by Complex I during anoxia. Mitochondr Physiol Network 24.02.
Perin G, Bellan A, Michelberger T, Lyska D, Wakao S, Niyogi KK, Morosinotto T (2023) Modulation of xanthophyll cycle impacts biomass productivity in the marine microalga Nannochloropsis. Proc Natl Acad Sci U S A 120:e2214119120. https://doi.org/10.1073/pnas.22141191202023PMID: 37307488 Open Access
Pallag G, Nazarian S, Ravasz D, Bui D, Komlódi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation supports mitochondrial ATP production when Complex I is inhibited. https://doi.org/10.3390/ijms230951112022Int J Mol Sci 23:5111. PMID: 35563503 Open Access
Pallag G, Nazarian S, Ravasz D, Bui D, Komlódi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation leading to high electron flow through reduction of ubiquinone supports ATP production by F1FO-ATPase in mitochondria with inhibited Complex I. https://doi.org/10.26124/mitofit:2022-0001.v32022-05-04 published in https://doi.org/10.3390/ijms230951112022MitoFit Preprints 2022.01.v3.
MitoFit pdf
Proline oxidation leading to high electron flow through reduction of ubiquinone supports ATP production by F1FO-ATPase in mitochondria with inhibited Complex I
P03.
Erich Gnaiger
Went N, Di Marcello M, Gnaiger Erich (2022) Oxygen dependence of photosynthesis and light-enhanced dark respiration studied by high-resolution PhotoRespirometry. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
»MitoFit Preprint«
Komlódi T, Cardoso LHD, Doerrier C, Moore AL, Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. Bioenerg Commun 2021.3. https://doi.org/10.26124/bec:2021-00032021Bioenerg Commun 2021.3. Open Access pdf published online 2021-11-11

Huete-Ortega M, Di Marcello M, Iglesias-Gonzalez J, Gnaiger E (2020) High-resolution respirometry for chloroplast and mitochondrial bioenergetics in Chlamydomonas reinhardtii ― towards biotechnology exploitations. https://doi.org/10.26124/mitofit:ea20.algaeurope.00012020MitoFit Preprint Arch EA20.1.
MitoFit pdf
High-resolution respirometry for chloroplast and mitochondrial bioenergetics in Chlamydomonas reinhardtii ― towards biotechnology exploitations
Donnelly C, Komlódi T, Cecatto C, Cardoso LHD, Compagnion A-C, Matera A, Tavernari D, Campiche O, Paolicelli RC, Zanou N, Kayser B, Gnaiger E, Place N (2024) Functional hypoxia reduces mitochondrial calcium uptake. Redox Biol 71:103037. https://doi.org/10.1016/j.redox.2024.1030372024PMID: 38401291 Open Access
Donnelly C, Komlódi T, Cecatto C, Cardoso LHD, Compagnion AC, Matera A, Tavernari D, Zanou N, Kayser B, Gnaiger E, Place N (2023) Functional hypoxia reduces mitochondrial calcium uptake. MitoFit Preprints 2023.2. https://doi.org/10.26124/mitofit:2023-00022023MitoFit Preprints 2023.2.
MitoFit pdf
Functional hypoxia reduces mitochondrial calcium uptake.
Doerrier C, Cardoso LHD, Gnaiger E (2022) Simultaneous measurement of oxygen consumption and NAD(P)H/NAD(P)+-redox state in isolated mitochondria. (in prep)
Copsey AC, Barsottini MRO, May B, Xu F, Albury MS, Young L, Moore AL (2021) Kinetic characterisation and inhibitor sensitivity of Candida albicans and Candida auris recombinant AOX expressed in a self-assembled proteoliposome system. Sci Rep 11:14748.2021PMID: 34285303 Open Access
Cardoso LHD, Doerrier C, Gnaiger E (2021) Magnesium Green for fluorometric measurement of ATP production does not interfere with mitochondrial respiration. Bioenerg Commun 2021.1. https://doi.org/10.26124/bec:2021-00012021Bioenerg Commun 2021.1. BEC pdf published online 2021-06-30

Balmaceda V, Komlodi T, Szibor M, Gnaiger E, Moore AL, Fernandez-Vizarra E, Viscomi C (2024) The striking differences in the bioenergetics of brain and liver mitochondria are enhanced in mitochondrial disease. Biochim Biophys Acta Mol Basis Dis 1870:167033. https://doi.org/10.1016/j.bbadis.2024.1670332024PMID: 38280294 Bioblast link
4.3. «10+5»
Luiza Cardoso
Cardoso Luiza HD, Doerrier C, Donnelly C, Komlódi T, Gnaiger E (2022) Redox monitoring and respiration - a new horizon with the NextGen-O2k. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«