Semantic search

Impairment of cardiac function and mitochondrial energy metabolism through diet induced obesity in aging.

Cecatto C, Schmitt Sabine, Cardoso L, Videja M, Dambrova M, Makrecka-Kuka M, Liepinsh E, Gnaiger E (2023) Contribution of fatty acid oxidation to respiratory control in brain mitochondria. 67th Annual Meeting of the Biophysical Society.

Timon-Gomez A, Cardoso L, Baglivo E, Doerrier C, Gnaiger E (2023) Mitochondrial injury in warm ischemia studied by high-resolution respirometry. EUROMIT2023 International Conference on Mitochondrial Pathology.

Human white adipose tissue mitochondrial respiration: effect of body composition

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude.

Bioenergetic profiling of kinase inhibitors reveals drug off-targer effects in colon cancer cell models

Leo E, Zdrazilova L, Garcia-Souza LF, Åsander-Frostner E, Elmér E, Gnaiger E (2023) High-resolution respirometry is comparable in 0.5 mL and 2.0 mL chamber volumes: studies with platelets, permeabilized fibroblasts, and isolated mitochondria. 57^th Annual Scientific Meeting of the European Society for Clinical Investigation.

Timón-Gómez A, Cardoso LHD, Doerrier C, Garcia-Souza LF, Gnaiger E (2023) A reference substrate-uncoupler-inhibitor titration protocol to create a mitochondrial pathway and coupling control database. Third international GIBB meeting.

P01.

Bettinazzi Stefano, Camus F, Dowling DK, Lane N (2022) Linking the mitonuclear genotype with mitochondrial function and organismal fitness. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001

6.5. «5 min»

Lerink Lente JS, Lindeman JHN (2022) Renal respiratory conductance: a complex matter. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001

5.1. «10+5»

Cecatto Cristiane, Cardoso LHD, Gnaiger E (2022) Mitochondrial calcium uptake capacity is lower than calcium retention capacity in the presence and absence of cyclosporin A. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001

7.2. «5 min»

Goulding Richie P, Strating S, van der Laan M, Noort W, Kolodyazhna A, Bloemers FW, Wüst RCI (2022) Mitochondrial function is not impaired in type 1 diabetes but does not respond to 4-weeks endurance training. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001

7.3. «5 min»

Colomb M, Tuifua L, Bertrand-Gaday C, Pessemesse L, Vernus B, Asikan E, Py G, Ollendorff V, Chabi Beatrice (2022) Coordination between mitochondrial-associated membranes MAMs, mitochondrial function and protein synthesis in exercised and myopathic muscles. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001

3.3. «5 min»

Granata Cesare (2022) Exercise training-induced enhancement of electron flow in the OXPHOS system is more important than increasing the OXPHOS machinery content to improve ATP generation in human skeletal muscle. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001

Gnaiger E (2022) Bioenergetic cluster analysis – diagnostic evaluation of mitochondrial respiratory control in human fibroblasts. 56^th Annual Scientific Meeting of the European Society for Clinical Investigation.

3.1. «10+5»

Komlódi Timea, Tretter L (2022) The protonmotive force – not merely membrane potential. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
»MitoFit Preprint«

Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Instrumental quality control and evaluation of mitochondrial respiration medium in high-resolution respirometry with living and permeabilized cells. EBEC 2022.

Schmitt S, Gnaiger E (2022) Short-term effect of molecular hydrogen on mitochondrial respiration and hydrogen peroxide production in permeabilized HEK 293T cells. EBEC 2022.

P09.

Ebanks Brad, Wang Y, Katyal G, Sargent C, Ingram TL, Bowman A, Moisoi N, Chakrabarti L (2022) Exercise alters mitochondrial physiology and has age-specific impacts on the fitness and lifespan of D. melanogaster. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001

Baglivo E, Cardoso LHD, Cecatto C, Gnaiger E (2022) Quality control of mitochondrial respiration medium in high-resolution respirometry with living and permeabilized cells. 56^th Annual Scientific Meeting of the European Society for Clinical Investigation.

Cardoso LHD, Donnelly C, Komlódi T, Gnaiger E (2022) Bioenergetic fingerprinting with coupling and pathway control of coenzyme Q redox state and respiration in permeabilized HEK 293T cells. 56^th Annual Scientific Meeting of the European Society for Clinical Investigation.

2.2. «10+5»

Schmitt Sabine, Gnaiger E (2022) Using oxygen and hydrogen gas in studies of mitochondrial respiration and hydrogen peroxide production under hyperoxic, normoxic, and hypoxic conditions. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001

Mitochondrial respiration in human skeletal muscle after 60 days of best rest.

Protective effect of nitrite in brain ischemia/reperfusion via modulation of mitochondrial respiration.

Mitochondrial respiration in muscle tissue of colon cancer patients.

Generating reference values on mitochondrial respiration in permeabilized muscle fibers.

Gestational physical exercise offers prolonged protection to liver mitochondrial function of female offspring against deleterious effects of maternal gestational diabetes.

Functional interactions between the Drosophila melanogaster mitochondrial glycerol-3-phosphate dehydrogenase and a xenotopically expressed alternative oxidase.

Aging effects on mitochondrial control factors in Pink1 knockout Drosophila melanogaster.

Methylation Controlled J protein (MCJ): A therapeutic target in hepatic ischemia and reperfusion injury.

Pathophysiology of type 2 diabetes and mitochondrial dysfunction: possible therapeutic implications.

The decline of mitochondrial respiration in isolated platelets after short-term storage.

Effects of glucose concentration in cell culture media on hepatocellular carcinoma HuH7 cells evaluated by high-resolution respirometry.

Involvement of mitochondrial respiratory supercomplexes in anti-bacterial innate immunity.

Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers.

The secrets of extreme longevity from bivalves.

Cell-permeable succinate bypasses statin-induced decrease in mitochondrial ATP-generating respiration in human platelets.

Peripheral blood mononuclear cells to detect mitochondrial dysfunction in horses: a preliminary study.

Investigating mitochondrial function in blood cells by high-resolution respirometry: contribution to an interlaboratory study. MitoEAGLE WG4.

Metabolic effects of mitochondria-targeted antioxidant peptides in colorectal cancer cells.

Effects of therapeutic metformin concentration on mitochondria in muscle cells.

Cell membrane permeabilization: digitonin optimization pitfalls.

Subchronic in vivo study for the evaluation of hepatic mitochondrial toxicity induced by silver nanoparticles.

AMPK deficiency elicits changes in OXPHOS in heart mitochondria.

Intracellular energy-transfer networks in health and disease – the results of oxygraphic studies.

Analysis of mitochondrial function in iron deficiency anemia and iron overload conditions.

High fat-load induces cardioprotection in hearts from obese mice.

Oscillations in mitochondrial ROS production during the early cell cycles in Xenopus embryos.

Inter-laboratory harmonization of protocols for mitochondrial function evaluation in permeabilized muscle fibers.

Role of mitochondria in skeletal muscle acclimatization to high-altitude.

Metabolic flexibility and mitochondrial function in the diabetic heart.

Maternal aging increases granulosa cell mitochondrial ROS release and reduces oocyte OXPHOS-linked respiration: implications for embryo development.

Skeletal muscle mitochondrial thermogenesis in hypermetabolic humans.

Neuroprotective compound R-phenibut protects brain mitochondria against anoxia-reoxygenation damage in vitro.

Evaluation of anaplerotic pathways to avoid artefacts in respirometric measurement of fatty acid oxidation.

Two populations of muscle mitochondria: heart and skeletal muscle.

Mitochondrial function during ischemia/reperfusion injury.

Role of succinate in prostate cancer cells: uptake and mitochondrial respiratory function.

Impact of western diet on energy metabolism in mouse liver.

Measurement of ROS production under hypoxia and unexpected methodological pitfalls of Amplex UltraRed assay.

Evidence of functional uncoupling protein 1 in the white adipose tissue of hypermetabolic humans.

High-resolution respirometry with a reduced chamber volume – which are the compromises in OXPHOS analysis?

The discovery of methyl-GBB - acylcarnitine lowering as an effective strategy to treat cardiometabolic diseases.

Cytoplasmic hybrid cells as a model to characterize the effect of the mtDNA mutations on the OXPHOS system.

Timing of feeding behavior affects daily rhythms in body temperature and muscle mitochondrial metabolism.

The relevance of ACBD3 protein in energy metabolism in various cell lines. Danhelovska_Presentation

Mitochondria, melatonin, and neuroinflammation in Parkinson's disease. Acuna-Castroviejo_Presentation

Aerobic/strength exercise intervention modulates skeletal muscle mitochondrial function in seniors.

High-resolution respirometry of neuroblastoma SH-SY 5Y cell line.

The structural molecular diversity of mitochondrial cardiolipins.

Different respiratory states to determine LEAK and uncoupled respiration in the SUIT protocol: effect and consequences.

Blood platelets as bioenergetic markers of brain damage in STZ-diabetes.

Bioenergetic comparison of human colorectal and breast cancer clinical patients.

Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats.

The effect of 24 weeks of high-fat and high-cholesterol diet on rat liver mitochondria. Sobotka_Presentation

Age-related responses of brain mitochondria to ischemic insult. Arandarcikaite_Presenation

Novel multivariate biomarkers of age-dependent sarcopenia: A blood based bioenergetics & cytokine profiling approach.

Mitochondrial respiration of isolated peripheral blood mononuclear cells in an experimental porcine brain injury model.

Oscillations in mitochondrial ROS production as a new mechanism for cell cycle control.

Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles.

Establishing cellular model for studying mechanisms of muscle insulin resistance: towards understanding the role of mitochondria.

Developing a method of assessing mitochondrial functions in homogenates of human heart muscle.

Mitochondrial fitness in skeletal muscle.