Semantic search
From Bioblast
Year | Reference | Mammal and model | Tissue and cell | Stress | Diseases | |
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Treberg 2018 Comp Biochem Physiol B Biochem Mol Biol | 2018 | Treberg JR, Braun K, Zacharias P, Kroeker K (2018) Multidimensional mitochondrial energetics: Application to the study of electron leak and hydrogen peroxide metabolism. Comp Biochem Physiol B Biochem Mol Biol 224:121-28. | Mouse Rat | Skeletal muscle | ||
Kappler 2018 Thesis | 2018 | Kappler L (2018) Method development for valid high‐resolution profiling of mitochondria and Omics investigation of mitochondrial adaptions to excess energy intake and physical exercise. Dissertation p181. | Human Mouse | Skeletal muscle Liver Other cell lines | Diabetes | |
Pamenter 2018 PLoS One | 2018 | Pamenter ME, Lau GY, Richards JG (2018) Effects of cold on murine brain mitochondrial function. PLoS One 13:e0208453. | Mouse | Nervous system | ||
Siira 2018 EMBO Rep | 2018 | Siira SJ, Rossetti G, Richman TR, Perks K, Ermer JA, Kuznetsova I, Hughes L, Shearwood AJ, Viola HM, Hool LC, Rackham O, Filipovska A (2018) Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z. EMBO Rep 19:e46198. | Mouse | Heart | Myopathy | |
Woodman 2018 FASEB J | 2018 | Woodman AG, Mah R, Keddie D, Noble RMN, Panahi S, Gragasin FS, Lemieux H, Bourque SL (2018) Prenatal iron deficiency causes sex-dependent mitochondrial dysfunction and oxidative stress in fetal rat kidneys and liver. FASEB J 32:3254-63. | Rat | Liver Kidney | ||
Rivas 2018 Am J Physiol Endocrinol Metab | 2018 | Rivas E, Herndon DN, Porter C, Meyer W, Suman OE. (2018) Short-term metformin and exercise training effects on strength, aerobic capacity, glycemic control, and mitochondrial function in children with burn injury.. Am J Physiol Endocrinol Metab. 314(3):E232-E240. | Human | Skeletal muscle | Other | |
Dandanell 2018 Scand J Med Sci Sports | 2018 | Dandanell S, Meinild-Lundby AK, Andersen AB, Lang PF, Oberholzer L, Keiser S, Robach P, Larsen S, Rønnestad BR, Lundby C (2018) Determinants of maximal whole-body fat oxidation in elite cross-country skiers: role of skeletal muscle mitochondria. Scand J Med Sci Sports 28:2494-504. | Human | Skeletal muscle | ||
Ederer 2018 Int J Mol Sci | 2018 | Ederer KA, Jin K, Bouslog S, Wang L, Gorman GS, Rowe GC, Abadir P, Raftery D, Moellering D, Promislow D, Jumbo-Lucioni P, De Luca M (2018) Age- and genotype-specific effects of the angiotensin-converting enzyme inhibitor lisinopril on mitochondrial and metabolic parameters in Drosophila melanogaster. Int J Mol Sci 19:3351. | Drosophila | Aging;senescence | ||
Paech 2018b Toxicology | 2018 | Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23. | Mouse | Liver | Cell death Cryopreservation | |
Manakov 2018 J Physiol Biochem | 2018 | Manakov D, Kolar D, Zurmanova J, Pravenec M, Novotny J (2018) Changes in the activity of some metabolic enzymes in the heart of SHR rat incurred by transgenic expression of CD36. J Physiol Biochem 74:479-89. | Rat | Heart | Cardiovascular | |
Fisher-Wellman 2018 Cell Rep | 2018 | Fisher-Wellman KH, Davidson MT, Narowski TM, Lin CT, Koves TR, Muoio DM (2018) Mitochondrial diagnostics: A multiplexed assay platform for comprehensive assessment of mitochondrial energy fluxes. Cell Rep 24:3593-606. | Mouse | Heart Skeletal muscle | ||
Gratl 2018 Thesis | 2018 | Gratl A (2018) High-resolution respirometry for measurement of mitochondrial function in PAD patients before and after revascularisation. PhD Thesis 69. | Human | Skeletal muscle | Ischemia-reperfusion | Cardiovascular |
Krug 2018 Thesis | 2018 | Krug KP (2018) Adaptation of metabolism and respiratory chain functions in pulmonary arterial vascular muscle cells under chronic hypoxia: especially considering the cytochrome c oxidase subunit 4 isoform 2. Doctoral Dissertation 136. | Rat | Other cell lines | Hypoxia | |
Meinild Lundby 2018 Acta Physiol (Oxf) | 2018 | Meinild Lundby AK, Jacobs RA, Gehrig S, de Leur J, Hauser M, Bonne TC, Flück D, Dandanell S, Kirk N, Kaech A, Ziegler U, Larsen S, Lundby C (2018) Exercise training increases skeletal muscle mitochondrial volume density by enlargement of existing mitochondria and not de novo biogenesis. Acta Physiol (Oxf) 222, e12905. | Human | Skeletal muscle | ||
Chung 2018 J Exp Biol | 2018 | Chung DJ, Sparagna GC, Chicco AJ, Schulte PM (2018) Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol 221. pii: jeb174458. | Fishes | Liver | Temperature | |
Park 2018 J Clin Invest | 2018 | Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ (2018) Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest 129:694-711. | Mouse | Fat | ||
Lund 2018 Acta Physiol (Oxf) | 2018 | Lund MT, Larsen S, Hansen M, Courraud J, Floyd AK, Støckel M, Helge JW, Dela F (2018) Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery. Acta Physiol (Oxf) 223:e13032. | Human | Skeletal muscle | Diabetes Obesity | |
Ferri 2018 Eur J Appl Physiol | 2018 | Ferri A, Panariti A, Miserocchi G, Rocchetti M, Buoli Comani G, Rivolta I, Bishop DJ (2018) Tissue specificity of mitochondrial adaptations in rats after 4 weeks of normobaric hypoxia. Eur J Appl Physiol 118:1641-52. | Rat | Heart Skeletal muscle | Hypoxia | |
Trewin 2018 Am J Physiol Regul Integr Comp Physiol | 2018 | Trewin AJ, Parker L, Shaw CS, Hiam D, Garnham AP, Levinger I, McConell GK, Stepto NK (2018) Acute HIIE elicits similar changes in human skeletal muscle mitochondrial H2O2 release, respiration and cell signaling as endurance exercise even with less work. Am J Physiol Regul Integr Comp Physiol 315:R1003-R1016. | Human | Skeletal muscle | ||
Einer 2018 Cell Mol Gastroenterol Hepatol | 2018 | Einer C, Leitzinger C, Lichtmannegger J, Eberhagen C, Rieder T, Borchard S, Wimmer R, Denk G, Popper B, Neff F, Polishchuk EV, Polishchuk RS, Hauck SM, von Toerne C, Müller JC, Karst U, Baral BS, DiSpirito AA, Kremer AE, Semrau J, Weiss KH, Hohenester S, Zischka H (2018) A high calorie diet aggravates mitochondrial dysfunction and triggers severe liver damage in Wilson disease rats. Cell Mol Gastroenterol Hepatol 7:571-96. | Rat | Liver | Inherited | |
Jang 2018 Intensive Care Med Exp | 2018 | Jang DH, MD, Khatri UG, Shortal BP, Kelly M, Lambert DS, Hardy K, Eckmann DM (2018) Alterations in mitochondrial respiration and reactive oxygen species in patients poisoned with carbon monoxide treated with hyperbaric oxygen. Intensive Care Med Exp 6:4. | Human | Blood cells | Oxidative stress;RONS | |
Warnsmann 2018 Mech Ageing Dev | 2018 | Warnsmann V, Meyer N, Hamann A, Kögel D, Osiewacz HD (2018) A novel role of the mitochondrial permeability transition pore in (-)-gossypol-induced mitochondrial dysfunction. Mech Ageing Dev 170:45-58. | Fungi | Permeability transition | ||
Cruz 2018 Chem Biol Interact | 2018 | Cruz LC, Ecker A, Rodrigues NR, Martins IK, Posser T, Maciel FE, Vargas MA, Barbosa NV, Franco JL (2018) Honey protects against wings posture error and molecular changes related to mitochondrial pathways induced by hypoxia/reoxygenation in adult Drosophila melanogaster. Chem Biol Interact 291:245-52. | Drosophila | Hypoxia | ||
Lee 2018 Neurol Genet | 2018 | Lee RG, Sedghi M, Salari M, Shearwood AJ, Stentenbach M, Kariminejad A, Goullee H, Rackham O, Laing NG, Tajsharghi H, Filipovska A (2018) Early-onset Parkinson disease caused by a mutation in CHCHD2 and mitochondrial dysfunction. Neurol Genet 4:e276. | Human | Fibroblast | Parkinson's | |
Jelenik 2018 Mol Metab | 2018 | Jelenik T, Dille M, Müller-Lühlhoff S, Kabra DG, Zhou Z, Binsch C, Hartwig S, Lehr S, Chadt A, Peters EMJ, Kruse J, Roden M, Al-Hasani H, Castañeda TR (2018) FGF21 regulates insulin sensitivity following long-term chronic stress. Mol Metab 16:126-38. | Mouse | Skeletal muscle | Other Diabetes | |
Thrush 2018 Int J Obes (Lond) | 2018 | Thrush AB, Antoun G, Nikpay M, Patten DA, DeVlugt C, Mauger JF, Beauchamp BL, Lau P, Reshke R, Doucet É, Imbeault P, Boushel R, Gibbings D, Hager J, Valsesia A, Slack R, Al-Dirbashi OY, Dent R, McPherson R, Harper ME (2018) Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism. Int J Obes (Lond) 42:353-62. | Human | Skeletal muscle | Obesity | |
Monaco 2018 Am J Physiol Regul Integr Comp Physiol | 2018 | Monaco CMF, Miotto PM, Huber JS, van Loon LJC, Simpson JA, Holloway GP (2018) Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats. Am J Physiol Regul Integr Comp Physiol 315:R191-R204. | Rat | Heart | ||
Harmuth 2018 Front Mol Neurosci | 2018 | Harmuth T, Prell-Schicker C, Weber JJ, Gellerich F, Funke C, Drießen S, Magg JCD, Krebiehl G, Wolburg H, Hayer SN, Hauser S, Krüger R, Schöls L, Riess O, Hübener-Schmid J (2018) Mitochondrial morphology, function and homeostasis are impaired by expression of an N-terminal calpain cleavage fragment of Ataxin-3. Front Mol Neurosci 11:368. | Mouse | Fibroblast | Inherited Neurodegenerative | |
Wu 2018 Adv Sci | 2018 | Wu S, Zhang A, Li S, Chatterjee S, Qi R, Segura-Ibarra V, Ferrari M, Gupte A, Blanco E, Hamilton DJ (2018) Polymer functionalization of isolated mitochondria for cellular transplantation and metabolic phenotype alteration. Adv Sci 1700530. | Mouse | Liver | Cancer | |
Stanford 2018 Cell Metab | 2018 | Stanford KI, Lynes MD, Takahashi H, Baer LA, Arts PJ, May FJ, Lehnig AC, Middelbeek RJW, Richard JJ, So K, Chen EY, Gao F, Narain NR, Distefano G, Shettigar VK, Hirshman MF, Ziolo MT, Kiebish MA, Tseng YH, Coen PM, Goodyear LJ (2018) 12,13-diHOME: an exercise-induced lipokine that increases skeletal muscle fatty acid uptake. Cell Metab 27:1111-20. | Human Mouse | Skeletal muscle | Temperature | |
Campbell 2018 Free Radic Biol Med | 2018 | Campbell MD, Duan J, Samuelson AT, Gaffrey MJ, Wang L, Bammler TK, Moore RJ, White CC, Kavanagh TJ, Voss JG, Szeto HH, Rabinovitch PS, Qian WJ, Marcinek DJ (2018) Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice. Free Radic Biol Med 134:268-81. | Mouse | Skeletal muscle | Oxidative stress;RONS | Aging;senescence |
Logan 2018 Mol Metab | 2018 | Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, Van Remmen H, Sonntag WE (2018) Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes. Mol Metab 9:141-55. | Mouse | Nervous system | Alzheimer's | |
MacMillan-Crow 2018 Intern Med Rev (Wash D C) | 2018 | MacMillan-Crow LA, Mayeux PR (2018) Female mice exhibit less renal mitochondrial injury but greater mortality using a comorbid model of experimental sepsis. Intern Med Rev (Wash D C) 4. | Mouse | Kidney | Sepsis | |
Cronin 2018 Nature | 2018 | Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 563:564-68. | Mouse | Lymphocyte | Cancer | |
Gonzalez-Freire 2018 Aging Cell | 2018 | Gonzalez-Freire M, Scalzo P, D'Agostino J, Moore ZA, Diaz-Ruiz A, Fabbri E, Zane A, Chen B, Becker KG, Lehrmann E, Zukley L, Chia CW, Tanaka T, Coen PM, Bernier M, de Cabo R, Ferrucci L (2018) Skeletal muscle ex vivo mitochondrial respiration parallels decline in vivo oxidative capacity, cardiorespiratory fitness, and muscle strength: the Baltimore longitudinal study of aging. Aging Cell 17. | Human | Skeletal muscle | Aging;senescence | |
Zhang 2018 J Mol Cell Cardiol | 2018 | Zhang G, Sheng M, Wang J, Teng T, Sun Y, Yang Q, Xu Z (2018) Zinc improves mitochondrial respiratory function and prevents mitochondrial ROS generation at reperfusion by phosphorylating STAT3 at Ser727. J Mol Cell Cardiol 118:169-82. | Mouse | Heart | Ischemia-reperfusion Hypoxia | |
Rossignoli 2018 J Nutr Biochem | 2018 | Rossignoli CP, Dechandt CRP, Souza AO, Sampaio IH, Vicentini TM, Teodoro BG, Neto MPC, Ferrari GD, Couto-Lima CA, Alberici LC (2018) Effects of intermittent dietary supplementation with conjugated linoleic acid and fish oil (EPA/DHA) on body metabolism and mitochondrial energetics in mice. J Nutr Biochem 60:16-23. | Mouse | Skeletal muscle Nervous system Liver Fat | ||
Lobo-Jarne 2018 Cell Rep | 2018 | Lobo-Jarne T, Nývltová E, Pérez-Pérez R, Timón-Gómez A, Molinié T, Choi A, Mourier A, Fontanesi F, Ugalde C, Barrientos A (2018) Human COX7A2L regulates complex III biogenesis and promotes supercomplex organization remodeling without affecting mitochondrial bioenergetics. Cell Rep 25:1786-99. | Human | HEK Other cell lines | ||
Niu 2018 Cancer Metab | 2018 | Niu X, Chen YJ, Crawford PA, Patti GJ (2018) Transport-exclusion pharmacology to localize lactate dehydrogenase activity within cells. Cancer Metab 6:19. | Human | HeLa | ||
Smenes 2018 Interact Cardiovasc Thorac Surg | 2018 | Smenes BT, Bækkerud FH, Slagsvold KH, Hassel E, Wohlwend M, Pinho M, Høydal M, Wisløff U, Rognmo Ø, Wahba A (2018) Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial. Interact Cardiovasc Thorac Surg 27:95-101. | Human | Heart | Ischemia-reperfusion | Aging;senescence Cardiovascular |
Logan 2018 Thesis | 2018 | Logan C (2018) Nitrate and nitrite differentially affect respiration in zebrafish during exercise. Honors Baccalaureate of Science in Nutrition p44. | Zebrafish | Skeletal muscle | ||
Singh 2018 Arch Toxicol | 2018 | Singh F, Zoll J, Duthaler U, Charles AL, Panajatovic MV, Laverny G, McWilliams TG, Metzger D, Geny B, Krähenbühl S, Bouitbir J (2018) PGC-1β modulates statin-associated myotoxicity in mice. Arch Toxicol 93:487-504. | Mouse | Skeletal muscle | Cell death Oxidative stress;RONS | Myopathy |
Sirsat 2018 Comp Biochem Physiol A Mol Integr Physiol | 2018 | Sirsat SKG, Dzialowski EM (2018) Ontogeny of skeletal and cardiac muscle mitochondria oxygen fluxes in two breeds of chicken. Comp Biochem Physiol A Mol Integr Physiol 215:20-7. | Birds | Heart Skeletal muscle | ||
Casal 2018 J Anim Sci | 2018 | Casal A, Garcia-Roche M, Navajas EA, Cassina A, Carriquiry M (2018) Hepatic mitochondrial function in Hereford steers with divergent residual feed intake phenotypes. J Anim Sci 96:4431-43. | Bovines | Liver | ||
Zhang 2018 J Gerontol A Biol Sci Med Sci | 2018 | Zhang X, Trevino MB, Wang M, Gardell SJ, Ayala JE, Han X, Kelly DP, Goodpaster BH, Vega RB, Coen PM (2018) Impaired mitochondrial energetics characterize poor early recovery of muscle mass following hind limb unloading in old mice. J Gerontol A Biol Sci Med Sci 73:1313-22. | Mouse | Skeletal muscle | Aging;senescence | |
Karlsson 2018 J Neurotrauma | 2018 | Karlsson M, Pukenas B, Chawla S, Ehinger JK, Plyler R, Stolow M, Gabello M, Hugerth M, Elmér E, Hansson MJ, Margulies S, Kilbaugh T (2018) Neuroprotective effects of cyclosporine in a porcine pre-clinical trial of focal traumatic brain injury. J Neurotrauma 36:14-24. | Pig | Nervous system | Other | |
Tripodi 2018 Biochim Biophys Acta Mol Cell Res | 2018 | Tripodi F, Castoldi A, Nicastro R, Reghellin V, Lombardi L, Airoldi C, Falletta E, Maffioli E, Scarcia P, Palmieri L, Alberghina L, Agrimi G, Tedeschi G, Coccetti P (2018) Methionine supplementation stimulates mitochondrial respiration. Biochim Biophys Acta Mol Cell Res 1865:1901-13. | Saccharomyces cerevisiae | |||
Efimova 2018 Thesis | 2018 | Efimova I (2018) Structural composition and functional properties of mitochondrial FoF1 ATP synthase on models of specific subunits deficiencies. PhD Thesis 94. | Human | HEK | ||
Razak 2018 RUMeS | 2018 | Razak SHA, Hassan H, Hakimi NH, Rani NA, Ibrahim NF, Ngah WZW, Makpol S, Damanhuri MHA, Karim NA, Tan JK (2018) Isolation of mitochondria and measurement of oxygen consumption rate by high-resolution respirometry in rat hippocampus. RUMeS 6:11-18. | Rat | Nervous system | ||
Vatner 2018 Aging Cell | 2018 | Vatner DE, Zhang J, Oydanich M, Guers J, Katsyuba E, Yan L, Sinclair D, Auwerx J, Vatner SF (2018) Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. Aging Cell 17:e12751. | Mouse | Fat | Aging;senescence | |
Kahl 2018 Stroke | 2018 | Kahl A, Stepanova A, Konrad C, Anderson C, Manfredi G, Zhou P, Iadecola C, Galkin A (2018) Critical role of flavin and glutathione in complex I-mediated bioenergetic failure in brain ischemia/reperfusion injury. Stroke 49:1223-31. | Mouse | Nervous system | Ischemia-reperfusion | |
Konopka 2018 Aging Cell | 2018 | Konopka AR, Laurin JL, Schoenberg HM, Reid JJ, Castor WM, Wolff CA, Musci RV, Safairad OD, Linden MA, Biela LM, Bailey SM, Hamilton KL, Miller BF (2018) Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults. Aging Cell 18:e12880. | Human | Skeletal muscle | Aging;senescence Diabetes | |
Torres 2018 Cell Metab | 2018 | Torres MJ, Kew KA, Ryan TE, Pennington ER, Lin CT, Buddo KA, Fix AM, Smith CA, Gilliam LA, Karvinen S, Lowe DA, Spangenburg EE, Zeczycki TN, Shaikh SR, Neufer PD (2018) 17β-estradiol directly lowers mitochondrial membrane microviscosity and improves bioenergetic function in skeletal muscle. Cell Metab 27:167-79. https://doi.org/10.1016/j.cmet.2017.10.003 | Mouse | Skeletal muscle | Diabetes | |
Kauppila 2018 Nucleic Acids Res | 2018 | Kauppila JHK, Bonekamp NA, Mourier A, Isokallio MA, Just A, Kauppila TES, Stewart JB, Larsson NG (2018) Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 46:6642-69. | Mouse | Aging;senescence | ||
Nielsen 2018 Neurosci Lett | 2018 | Nielsen B, Cejvanovic V, Wörtwein G, Hansen AR, Marstal KK, Weimann A, Bjerring PN, Dela F, Poulsen HE, Jørgensen MB (2018) Increased oxidation of RNA despite reduced mitochondrial respiration after chronic electroconvulsive stimulation of rat brain tissue. Neurosci Lett 690:1-5. | Rat | Nervous system | Other | |
Goncalves 2018 Neurotoxicology | 2018 | Gonçalves DF, Courtes AA, Hartmann DD, da Rosa PC, Oliveira DM, Soares FAA, Dalla Corte CL (2018) 6-Hydroxydopamine induces different mitochondrial bioenergetics response in brain regions of rat. Neurotoxicology 70:1-11. | Rat | Nervous system | Parkinson's Neurodegenerative | |
Scaini 2018 Eur Neuropsychopharmacol | 2018 | Scaini G, Quevedo J, Velligan D, Roberts DL, Raventos H, Walss-Bass C (2018) Second generation antipsychotic-induced mitochondrial alterations: Implications for increased risk of metabolic syndrome in patients with schizophrenia. Eur Neuropsychopharmacol 28:369-80. | Human | Other cell lines Lymphocyte | Other | |
Barca 2018 Hum Mol Genet | 2018 | Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick E, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ (2018) USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis. Hum Mol Genet 27:3305-12. | Human | Fibroblast | Other Neurodegenerative | |
Zhang 2018 Aging Dis | 2018 | Zhang L, Hao J, Zheng Y, Su R, Liao Y, Gong X, Liu L, Wang X (2018) Fucoidan protects dopaminergic neurons by enhancing the mitochondrial function in a rotenone-induced rat model of Parkinson’s disease. Aging Dis 9:590-604. | Rat | Nervous system | Parkinson's | |
Tetri 2018 Front Physiol | 2018 | Tetri LH, Diffee GM, Barton GP, Braun RK, Yoder HE, Haraldsdottir K, Eldridge MW, Goss KN (2018) Sex-specific skeletal muscle fatigability and decreased mitochondrial oxidative capacity in adult rats exposed to postnatal hyperoxia. Front Physiol 9:326. | Rat | Skeletal muscle | Hypoxia | |
Scalzo 2018 Physiol Rep | 2018 | Scalzo RL, Knaub LA, Hull SE, Keller AC, Hunter K, Walker LA, Reusch JEB (2018) Glucagon-like peptide-1 receptor antagonism impairs basal exercise capacity and vascular adaptation to aerobic exercise training in rats. Physiol Rep 6:e13754. | Rat | Heart | ||
Flis 2018 Oxid Med Cell Longev | 2018 | Flis DJ, Dzik K, Kaczor JJ, Halon-Golabek M, Antosiewicz J, Wieckowski MR, Ziolkowski W (2018) Swim training modulates skeletal muscle energy metabolism, oxidative stress, and mitochondrial cholesterol content in amyotrophic lateral sclerosis mice. Oxid Med Cell Longev 5940748. | Mouse | Skeletal muscle | Neurodegenerative | |
Schiffer 2018 Am J Physiol Renal Physiol | 2018 | Schiffer TA, Gustafsson H, Palm F (2018) Kidney outer medulla mitochondria are more efficient compared with cortex mitochondria as a strategy to sustain ATP production in a suboptimal environment. Am J Physiol Renal Physiol 315:F677-F681. | Rat | Kidney | ||
Treberg 2018 Redox Biol | 2018 | Treberg JR, Braun K, Selseleh P (2018) Mitochondria can act as energy-sensing regulators of hydrogen peroxide availability. Redox Biol 20:483-88. | Rat | Skeletal muscle | ||
Astrakhanova 2018 Sovrem Tekhnologii Med | 2018 | Astrakhanova ТА, Urazov МD, Usenko АV, Mitroshina ЕV, Mishchenko ТА, Schelchkova NА, Vedunova МV (2018) BDNF-mediated regulation of the brain mitochondria functional state in hypoxia. Sovrem Tekhnologii Med 10:88-94. | Mouse | Nervous system | Hypoxia | |
Christen 2018 Free Radic Biol Med | 2018 | Christen F, Desrosiers V, Dupont-Cyr BA, Vandenberg GW, Le François NR, Tardif JC, Dufresne F, Lamarre SG, Blier PU (2018) Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production. Free Radic Biol Med 116:11-8. | Fishes | Heart | Temperature | Cardiovascular |
Salin 2018 Funct Ecol | 2018 | Salin K, Villasevil EM, Anderson GJ, Auer SK, Selman C, Hartley RC, Mullen W, Chinopoulos C, Metcalfe NB (2018) Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost. Funct Ecol DOI: 10.1111/1365-2435.13125. | Fishes | Liver | Oxidative stress;RONS | |
Okerblom 2018 Proc Biol Sci | 2018 | Okerblom J, Fletes W, Patel HH, Schenk S, Varki A, Breen EC (2018) Human-like Cmah inactivation in mice increases running endurance and decreases muscle fatigability: implications for human evolution. Proc Biol Sci 285:20181656. | Mouse | Skeletal muscle | ||
Reutzel 2018 Oxid Med Cell Longev | 2018 | Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP (2018) Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice. Oxid Med Cell Longev 2018:4070935. | Mouse | Nervous system | Aging;senescence | |
Bhaskaran 2018 EMBO Rep | 2018 | Bhaskaran S, Pharaoh G, Ranjit R, Murphy A, Matsuzaki S, Nair BC, Forbes B, Gispert S, Auburger G, Humphries KM, Kinter M, Griffin TM, Deepa SS (2018) Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance. EMBO Rep 19. pii: e45009. | Mouse | Fat | Diabetes Obesity | |
Silaidos 2018 Biol Sex Differ | 2018 | Silaidos C, Pilatus U, Grewal R, Matura S, Lienerth B, Pantel J, Eckert GP (2018) Sex-associated differences in mitochondrial function in human peripheral blood mononuclear cells (PBMCs) and brain. Biol Sex Differ 9:34. | Human | Nervous system Blood cells | Alzheimer's | |
Van Den Brink 2018 PLoS Genet | 2018 | Van Den Brink DM, Cubizolle A, Chatelain G, Davoust N, Girard V, Johansen S, Napoletano F, Dourlen P, Guillou L, Angebault-Prouteau C, Bernoud-Hubac N, Guichardant M, Brabet P, Mollereau B (2018) Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina. PLoS Genet 14:e1007627. | Mouse | Endothelial;epithelial;mesothelial cell | Neurodegenerative | |
Klepinin 2018 J Bioenerg Biomembr | 2018 | Klepinin A, Ounpuu L, Mado K, Truu L, Chekulayev V, Puurand M, Shevchuk I, Tepp K, Planken A, Kaambre T (2018) The complexity of mitochondrial outer membrane permeability and VDAC regulation by associated proteins. J Bioenerg Biomembr 50:339-54. | Mouse | Heart Neuroblastoma | ||
De Moura Alvorcem 2018 Mitochondrion | 2018 | De Moura Alvorcem L, Britto R, Parmeggiani B, Glanzel NM, Da Rosa-Junior NT, Cecatto C, Bobermin LD, Amaral AU, Wajner M, Leipnitz G (2018) Evidence that thiol group modification and reactive oxygen species are involved in hydrogen sulfide-induced mitochondrial permeability transition pore opening in rat cerebellum. Mitochondrion 47:141-50. | Rat | Nervous system | Permeability transition Oxidative stress;RONS | |
Perks 2018 Cell Rep | 2018 | Perks KL, Rossetti G, Kuznetsova I, Hughes LA, Ermer JA, Ferreira N, Busch JD, Rudler DL, Spahr H, Schöndorf T, Shearwood AJ, Viola HM, Siira SJ, Hool LC, Milenkovic D, Larsson NG, Rackham O, Filipovska A (2018) PTCD1 is required for 16S rRNA maturation complex stability and mitochondrial ribosome assembly. Cell Rep 23:127-42. | Mouse | Heart | ||
Kovalcikova 2018 Thesis | 2018 | Kovalčíková J (2018) Functional characterisation of new components of mitochondrial proteome. PhD Thesis p104. | Mouse Rat | Heart Liver | ||
Kleszczynski 2018 Int J Mol Sci | 2018 | Kleszczyński K, Bilska B, Stegemann A, Flis DJ, Ziolkowski W, Pyza E, Luger TA, Reiter RJ, Böhm M, Slominski AT (2018) Melatonin and its metabolites ameliorate UVR-induced mitochondrial oxidative stress in human MNT-1 melanoma cells. Int J Mol Sci 19:E3786. | Mouse | Liver | Oxidative stress;RONS | |
Kong 2018 Proteomics | 2018 | Kong D, Tian X, Li Y*, Zhang S, Cheng Y, Huo L, Ma H, Yang Z, Ren L, Zhang M, Zhang W (2018) Revealing the inhibitory effect of ginseng on mitochondrial respiration through synaptosomal proteomics. Proteomics 18:e1700354. | Rat | Nervous system | ||
Lander 2018 J Biol Chem | 2018 | Lander N, Chiurillo MA, Bertolini MS, Storey M, Vercesi AE, Docampo R (2018) Calcium-sensitive pyruvate dehydrogenase phosphatase is required for energy metabolism, growth, differentiation, and infectivity of Trypanosoma cruzi. J Biol Chem 293:17402-17. | Protists | |||
Thompson 2018 EMBO Mol Med | 2018 | Thompson K, Mai N, Oláhová M, Scialó F, Formosa LE, Stroud DA, Garrett M, Lax NZ, Robertson FM, Jou C, Nascimento A, Ortez C, Jimenez-Mallebrera C, Hardy SA, He L, Brown GK, Marttinen P, McFarland R, Sanz A, Battersby BJ, Bonnen PE, Ryan MT, Chrzanowska-Lightowlers ZM, Lightowlers RN, Taylor RW (2018) OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect. EMBO Mol Med 10:e9060. | Drosophila | |||
Boutoual 2018 Sci Rep | 2018 | Boutoual R, Meseguer S, Villarroya M, Martín-Hernández E, Errami M, Martín MA, Casado M, Armengod ME (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARγ-UCP2-AMPK axis. Sci Rep 8:1163. | Human | Fibroblast | Hypoxia | |
Dejmek 2018 Physiol Res | 2018 | Dejmek J, Kohoutová M, Kripnerová M, Čedíková M, Tůma Z, Babuška V, Bolek L, Kuncová J (2018) Repeated exposure to hyperbaric hyperoxia affects mitochondrial functions of the lung fibroblasts. Physiol Res 67(Suppl 4):S633-S643. | Human | Lung;gill Fibroblast | Oxidative stress;RONS | |
Durand 2018 Blood Purif | 2018 | Durand PY, Nicco C, Serteyn D, Attaf D, Edeas M (2018) Microbiota quality and mitochondrial activity link with occurrence of muscle cramps in hemodialysis patients using citrate dialysate: a pilot study. Blood Purif 46:301-8. | Human | Platelet Blood cells | ||
Francisco 2018 J Neurochem | 2018 | Francisco A, Ronchi JA, Navarro CDC, Figueira TR, Castilho RF (2018) Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet. J Neurochem 147:663-77. | Mouse | Nervous system | ||
Davis 2018 FASEB J | 2018 | Davis RAH, Deemer SE, Bergeron JM, Little JT, Warren JL, Fisher G, Smith DL Jr, Fontaine KR, Dickinson SL, Allison DB, Plaisance EP (2018) Dietary R, S-1,3-butanediol diacetoacetate reduces body weight and adiposity in obese mice fed a high-fat diet. FASEB J 33:2409-21. | Mouse | Skeletal muscle | Obesity | |
Dawson 2018 Acta Physiol (Oxf) | 2018 | Dawson NJ, Lyons SA, Henry DA, Scott GR (2018) Effects of chronic hypoxia on diaphragm function in deer mice native to high altitude. Acta Physiol (Oxf) 223:e13030. | Other mammals | Skeletal muscle | Hypoxia | |
Anderson 2017 Cell Metab | 2017 | Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD (2017) SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion. Cell Metab 25:838-55. | Mouse | Heart Liver | Aging;senescence Diabetes | |
Sivertsson 2017 Am J Physiol Renal Physiol | 2017 | Sivertsson E, Friederich-Persson M, Öberg CM, Fasching A, Hansell P, Rippe B, Palm F (2017) Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability. Am J Physiol Renal Physiol 314:F864-F872. | Rat | Kidney | Diabetes | |
Gusdon 2017 Exp Gerontol | 2017 | Gusdon AM, Callio J, Distefano G, O'Doherty RM, Goodpaster BH, Coen PM, Chu CT (2017) Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice. Exp Gerontol 90:1-13. | Mouse | Nervous system | Oxidative stress;RONS | Aging;senescence |
Schmidt 2017 J Vasc Surg | 2017 | Schmidt CA, Ryan TE, Lin CT, Inigo MM, Green TD, Brault JJ, Spangenburg EE, McClung JM (2017) Diminished force production and mitochondrial respiratory deficits are strain-dependent myopathies of subacute limb ischemia. J Vasc Surg 65:1504-1514. | Mouse | Skeletal muscle | Hypoxia | Myopathy Other |
Comelli 2017 J Bioenerg Biomembr | 2017 | Comelli M, Pretis I, Buso A, Mavelli I (2017) Mitochondrial energy metabolism and signalling in human glioblastoma cell lines with different PTEN gene status. J Bioenerg Biomembr 50:33-52. | Human | Nervous system | Cancer | |
Jackson 2017 Cancer Res | 2017 | Jackson LE, Kulkarni S, Wang H, Lu J, Dolezal JM, Bharathi SS, Ranganathan S, Patel MS, Deshpande R, Alencastro F, Wendell SG, Goetzman ES, Duncan AW, Prochownik EV (2017) Genetic dissociation of glycolysis and the TCA cycle affects neither normal nor neoplastic proliferation. Cancer Res 77:5795-807. | Mouse | Liver | Cancer | |
Nogueira 2017 Free Radic Biol Med | 2017 | Nogueira NP, Saraiva FMS, Oliveira MP, Mendonca APM, Inacio JDF, Almeida-Amaral EE, Menna-Barreto RF, Laranja GAT, Lopes Torres EJ, Oliveira MF, Paes MC (2017) Heme modulates Trypanosoma cruzi bioenergetics inducing mitochondrial ROS production. Free Radic Biol Med 108:183-91. | Protists | Oxidative stress;RONS | ||
Jelenik 2017 Diabetes | 2017 | Jelenik T, Kaul K, Séquaris G, Flögel U, Phielix E, Kotzka J, Knebel B, Fahlbusch P, Hörbelt T, Lehr S, Reinbeck AL, Müller-Wieland D, Esposito I, Shulman GI, Szendroedi J, Roden M (2017) Mechanisms of insulin resistance in primary and secondary nonalcoholic fatty liver. Diabetes 66:2241-53. | Mouse | Skeletal muscle Liver | Diabetes Other | |
Lou 2017 Physiol Rep | 2017 | Lou PH, Lucchinetti E, Scott KY, Huang Y, Gandhi M, Hersberger M, Clanachan AS, Lemieux H, Zaugg M (2017) Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats. Physiol Rep 5 pii: e13388. | Rat | Heart | Diabetes | |
Chavanelle 2017 Sci Rep | 2017 | Chavanelle V, Boisseau N, Otero YF, Combaret L, Dardevet D, Montaurier C, Delcros G, Peltier SL, Sirvent P (2017) Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice. Sci Rep 7:204. | Mouse | Skeletal muscle | Diabetes | |
Holland 2017 Placenta | 2017 | Holland OJ, Hickey AJR, Alvsaker A, Moran S, Hedges C, Chamley LW, Perkins AV (2017) Changes in mitochondrial respiration in the human placenta over gestation. Placenta 57:102-12. | Genital | |||
Porter 2017 Adipocyte | 2017 | Porter C (2017) Quantification of UCP1 function in human brown adipose tissue. Adipocyte 6:167-74. | Fat | |||
Bowen 2017 J Am Heart Assoc | 2017 | Bowen TS, Brauer D, Rolim NPL, Bækkerud FH, Kricke A, Ormbostad Berre AM, Fischer T, Linke A, da Silva GJ, Wisloff U, Adams V (2017) Exercise training reveals inflexibility of the diaphragm in an animal model of patients with obesity-driven heart failure with a preserved ejection fraction. J Am Heart Assoc 6. pii: e006416. | Rat | Skeletal muscle | Cardiovascular Obesity | |
Fourcade 2017 Aging Cell | 2017 | Fourcade S, Morató L, Parameswaran J, Ruiz M, Ruiz-Cortés T, Jové M, Naudí A, Martínez-Redondo P, Dierssen M, Ferrer I, Villarroya F, Pamplona R, Vaquero A, Portero-Otín M, Pujol A (2017) Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. Aging Cell 16:1404-13. | Mouse | Aging;senescence Neurodegenerative | ||
Linden 2016 Am J Physiol Gastrointest Liver Physiol | 2017 | Linden MA, Fletcher JA, Meers GM, Thyfault JP, Laughlin MH, Rector RS (2017) A return to ad libitum feeding following caloric restriction promotes hepatic steatosis in hyperphagic OLETF rats. Am J Physiol Gastrointest Liver Physiol 311:G387-95. | Rat | Liver | Obesity | |
Du 2017 Evolution | 2017 | Du SNN, Khajali F, Dawson NJ, Scott GR (2017) Hybridization increases mitochondrial production of reactive oxygen species in sunfish. Evolution 71:1643-52. | Fishes | Liver | Oxidative stress;RONS Ischemia-reperfusion | |
Abdurrachim 2017 Cardiovasc Res | 2017 | Abdurrachim D, Nabben M, Hoerr V, Kuhlmann MT, Bovenkamp P, Ciapaite J, Geraets IME, Coumans W, Luiken JJFP, Glatz JFC, Schäfers M, Nicolay K, Faber C, Hermann S, Prompers JJ (2017) Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. Cardiovasc Res 113:1148-60. | Mouse | Heart | Diabetes | |
Khalifa 2017 Physiol Rep | 2017 | Khalifa AR, Abdel-Rahman EA, Mahmoud AM, Ali MH, Noureldin M, Saber SH, Mohsen M, Ali SS (2017) Sex-specific differences in mitochondria biogenesis, morphology, respiratory function, and ROS homeostasis in young mouse heart and brain. Physiol Rep 5. pii: e13125. | Mouse | Heart Nervous system | Aging;senescence Cardiovascular Other | |
Gruenig 2017 Toxicol In Vitro | 2017 | Grünig D, Felser A, Bouitbir J, Krähenbühl S (2017) The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells. Toxicol In Vitro 42:337-47. | Human Mouse | Liver Other cell lines | ||
Yeh 2017 Thesis | 2017 | Yeh A (2017) Modulation of mitochondrial function as an indicator for sublethal effects of contaminants of emerging concern. Dissertation p117. | Human Fishes | Liver | ||
Chin 2017 US Patent | 2017 | Chin MT, Chien WM, Dinca A (2017) Methods for treating and preventing cardiomyopathy. US Patent WO2016094791A1. | Mouse | Heart | Inherited Myopathy | |
Lee 2017 Am J Physiol Endocrinol Metab | 2017 | Lee S, Leone TC, Rogosa L, Rumsey J, Ayala J, Coen PM, Fitts RH, Vega RB, Kelly DP (2017) Skeletal muscle PGC-1β signaling is sufficient to drive an endurance exercise phenotype and to counteract components of detraining in mice. Am J Physiol Endocrinol Metab 312:E394-406. | Mouse | Skeletal muscle | ||
Rodrigues-Silva 2017 J Neurooncol | 2017 | Rodrigues-Silva E, Siqueira-Santos ES, Ruas JS, Ignarro RS, Figueira TR, Rogério F, Castilho RF (2017) Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity. 10.1007/s11060-017-2482-0 | Rat | Nervous system | Cancer | |
De Lourdes Jorge 2017 Transplant Proc | 2017 | de Lourdes Jorge G, Dos Reis Tártaro R, Fazzio Escanhoela CA, Boin IFSF (2017) Later evaluation of ischemia and reperfusion by the Pringle maneuver in Wistar rats, demonstrating that hepatic lesions can be reversible. Transplant Proc 49:898-901. | Rat | Liver | Ischemia-reperfusion | |
Leo 2017 Front Zool | 2017 | Leo E, Kunz KL, Schmidt M, Storch D, Portner HO, Mark FC (2017) Mitochondrial acclimation potential to ocean acidification and warming of Polar cod (Boreogadus saida) and Atlantic cod (Gadus morhua). Front Zool 14:21. | Fishes | Heart | Temperature | |
Thomas 2017 Thesis | 2017 | Thomas NO (2017) Age-related decrease in resilience against acute redox cycling agents: critical role of declining GSH-dependent detoxification capacity. Dissertation p141. | Rat | Liver | Aging;senescence | |
Koit 2017 Oxid Med Cell Longev | 2017 | Koit A, Shevchuk I, Ounpuu L, Klepinin A, Chekulayev V, Timohhina N, Tepp K, Puurand M,Truu L, Heck K, Valvere V, Guzun R, Kaambre T (2017) Mitochondrial respiration in human colorectal and breast cancer clinical material is regulated differently. Oxid Med Cell Longev 2017:1372640. | Human | Endothelial;epithelial;mesothelial cell | Cancer | |
Ortega-Dominguez 2017 Food Chem Toxicol | 2017 | Ortega-Domínguez B, Aparicio-Trejo OE, García-Arroyo FE, León-Contreras JC, Tapia E, Molina-Jijón E, Hernández-Pando R, Sánchez-Lozada LG, Barrera-Oviedo D, Pedraza-Chaverri J (2017) Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic. Food Chem Toxicol 107:373-85. | ||||
Qi 2017 Ann Allergy Asthma Immunol | 2017 | Qi S, Cindy Barnig C, Charles AL, Poirot A, Meyer A, Clere-Jehl R, de Blay F, Geny B (2017) Nasal allergen challenge in allergic rhinitis induces mitochondrial dysfunction of peripheral blood mononuclear cells. Ann Allergy Asthma Immunol 118:367-9. | Human | Blood cells Lymphocyte | Other | |
Teplova 2017 Toxicol Lett | 2017 | Teplova VV, Belosludtsev KN, Kruglov AG (2017) Mechanism of triclosan toxicity: Mitochondrial dysfunction including complex II inhibition, superoxide release and uncoupling of oxidative phosphorylation. Toxicol Lett 275:108-17. | Rat | Liver | ||
Bal 2017 J Biol Chem | 2017 | Bal NC, Singh S, Reis FCG, Maurya SK, Pani S, Rowland LA, Periasamy M (2017) Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice. J Biol Chem 292:16616-25. | Mouse | Skeletal muscle Fat | Temperature | |
Rontoyanni 2017 Shock | 2017 | Rontoyanni VG, Malagaris I, Herndon DN, Rivas E, Capek KD, Delgadillo AD, Bhattarai N, Elizondo A, Voigt CD, Finnerty CC, Suman OE, Porter C (2017) Skeletal muscle mitochondrial function is determined by burn severity, sex and sepsis, and is associated with glucose metabolism and functional capacity in burned children. Shock 50:141-48. | Human | Skeletal muscle | Sepsis | |
Huang 2017 Sci Rep | 2017 | Huang L, Zhang K, Guo Y, Huang F, Yang K, Chen L, Huang K, Zhang F, Long Q, Yang Q (2017) Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts. Sci Rep 7:11989. | Mouse | Heart | Cancer | |
Edgett 2017 Thesis | 2017 | Edgett B (2017) Regulation of SIRT1, SIRT3, PGC-1α, and LRP130 in response to energetic stress in human skeletal muscle. Doctoral Dissertation p145. | Human | Skeletal muscle | ||
Thaher 2017 Neurochem Int | 2017 | Thaher O, Wolf C, Dey PN, Pouya A, Wüllner V, Tenzer S, Methner A (2017) The thiol switch C684 in Mitofusin-2 mediates redox-induced alterations of mitochondrial shape and respiration. Neurochem Int 117:167-73. | Mouse | Fibroblast | ||
Dixit 2017 Free Radic Biol Med | 2017 | Dixit S, Fessel JP, Harrison FE (2017) Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate. Free Radic Biol Med 112:515-23. | Mouse | Heart | Alzheimer's | |
Liu 2017 Physiol Rep | 2017 | Liu A, Philip J, Vinnakota KC, Van den Bergh F, Tabima DM, Hacker T, Beard DA, Chesler NC (2017) Estrogen maintains mitochondrial content and function in the right ventricle of rats with pulmonary hypertension. Physiol Rep 5:e13157. | Rat | Heart | Other | |
Sharaf 2017 Biochim Biophys Acta | 2017 | Sharaf MS, Stevens D, Kamunde C (2017) Mitochondrial transition ROS spike (mTRS) results from coordinated activities of complex I and nicotinamide nucleotide transhydrogenase. Biochim Biophys Acta 1858:955-65. | Mouse Fishes | Heart Liver | Oxidative stress;RONS | |
Hals 2017 Physiol Rep | 2017 | Hals I, Ohki T, Singh R, Ma Z, Björklund A, Balasuriya C, Scholz H, Grill V (2017) Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates. Physiol Rep 5. pii: e13447. | Human Mouse | Islet cell;pancreas;thymus | Hypoxia | |
Mitroshina 2017 Mod Technol Med | 2017 | Mitroshina ЕV, Abogessimengane BZ, Urazov МD, Hamraoui I, Mishchenko ТА, Astrakhanova ТА, Shchelchkova NА, Lapshin RD, Shishkina ТV, Belousova II, Mukhina IV, Vedunova МV (2017) Adaptive role of glial cell line-derived neurotrophic factor in cerebral ischemia. Mod Technol Med 9:68-76. | Mouse | Nervous system | Ischemia-reperfusion | |
Wetzel 2017 Thesis | 2017 | Wetzel MD (2017) Mechanism of metformin action in dermal fibroblasts. PhD Thesis 125. | Human | Fibroblast | Other | |
Gerber 2017 Brain | 2017 | Gerber S, Charif M, Chevrollier A, Chaumette T, Angebault C, Kane MS, Paris A, Alban J, Quiles M, Delettre C, Bonneau D, Procaccio V, Amati-Bonneau P, Reynier P, Leruez S, Calmon R, Boddaert N, Funalot B, Rio M, Bouccara D, Meunier I, Sesaki H, Kaplan J, Hamel CP, Rozet JM, Lenaers G (2017) Mutations in DNM1L, as in OPA1, result indominant optic atrophy despite opposite effects on mitochondrial fusion and fission. Brain 140:2586-96. | Human | Endothelial;epithelial;mesothelial cell Fibroblast | Other | |
Dolezal 2017 J Biol Chem | 2017 | Dolezal JM, Wang H, Kulkarni S, Jackson L, Lu J, Ranganathan S, Goetzman ES, Bharathi SS, Beezhold K, Byersdorfer CA, Prochownik EV (2017) Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma. J Biol Chem 292:10068-86. | Mouse | Liver | Cancer | |
Mottahedin 2017 J Cereb Blood Flow Metab | 2017 | Mottahedin A, Svedin P, Nair S, Mohn CJ, Wang X, Hagberg H, Ek J, Mallard C (2017) Systemic activation of Toll-like receptor 2 suppresses mitochondrial respiration and exacerbates hypoxic-ischemic injury in the developing brain. J Cereb Blood Flow Metab 37:1192-8. | Mouse | Nervous system | Ischemia-reperfusion | Other |
Jahandiez 2017 Basic Res Cardiol | 2017 | Jahandiez V, Cour M, Bochaton T, Abrial M, Loufouat J, Gharib A, Varennes A, Ovize M, Argaud L (2017) Fast therapeutic hypothermia prevents post-cardiac arrest syndrome through cyclophilin D-mediated mitochondrial permeability transition inhibition. Basic Res Cardiol 112:35. | Rabbit | Heart Nervous system | Permeability transition Temperature | Cardiovascular |
Stepanova 2017 J Cereb Blood Flow Metab | 2017 | Stepanova A, Kahl A, Konrad C, Ten V, Starkov AS, Galkin A (2017) Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia-reperfusion injury. J Cereb Blood Flow Metab 37:3649-58. | Mouse | Nervous system | Ischemia-reperfusion | |
Cervoni 2017 J Exp Biol | 2017 | Cervoni MS, Cardoso-Júnior CAM, Craveiro G, Souza AO, Alberici LC, Hartfelder K (2017) Mitochondrial capacity, oxidative damage and hypoxia gene expression are associated with age-related division of labor in honey bee (Apis mellifera L.) workers. J Exp Biol 220:4035-46. | ||||
Tepp 2017 Mol Cell Biochem | 2017 | Tepp K, Puurand M, Timohhina N, Adamson J, Klepinin A, Truu L, Shevchuk I, Chekulayev V, Kaambre T (2017) Changes in the mitochondrial function and in the efficiency of energy transfer pathways during cardiomyocyte aging. Mol Cell Biochem 432:141-58. | Rat | Heart | Aging;senescence | |
Merz 2017 Intensive Care Med Exp | 2017 | Merz T, Vogt JA, Wachter U, Calzia E, Szabo C, Wang R, Radermacher P, McCook O (2017) Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock. Intensive Care Med Exp 5:30. | Mouse | Liver | Sepsis | |
Cockova 2017 Thesis | 2017 | Čočková Z (2017) Modulation of RNA demethylase FTO function in SH-SY5Y cells: the effect on insulin signaling and mitochondrial respiration. Diploma Thesis p70. | Human | Nervous system | Cancer | |
Vienne 2017 Anal Biochem | 2017 | Vienne JC, Cimetta C, Dubois M, Duburcq T, Favory R, Dessein AF, Fontaine M, Joncquel-Chevalier Curt M, Cuisset JM, Douillard C, Mention-Mulliez K, Dobbelaere D, Vamecq J (2017) A fast method for high resolution oxymetry study of skeletal muscle mitochondrial respiratory chain complexes. Anal Biochem 528:57-62. | Pig | Skeletal muscle | ||
Jang 2017 Clin Toxicol (Phila) | 2017 | Jang DH, Kelly M, Hardy K, Lambert DS, Shofer FS, Eckmann DM (2017) A preliminary study in the alterations of mitochondrial respiration in patients with carbon monoxide poisoning measured in blood cells. Clin Toxicol (Phila) 55:579-84. | Blood cells | |||
Darrell 2017 US Patent | 2017 | Neufer PD, Anderson EJ, Szeto HH (2017) Methods for preventing or treating insulin resistance. US Patent US20170100450 A1. | Human Rat | Skeletal muscle | Diabetes Obesity | |
Fisar 2017 Indian J Biochem Biophys | 2017 | Fišar Z, Hroudová J, Namrata S, Macečková D, Kopřivová A (2017) Protocols for high-resolution respirometry experiments to test the activity of electron transfer system of pig brain mitochondria. Indian J Biochem Biophys 54:258-72. | Pig | Nervous system | ||
Newsom 2017 Am J Physiol Endocrinol Metab | 2017 | Newsom SA, Miller BF, Hamilton KL, Ehrlicher SE, Stierwalt HD, Robinson MM (2017) Long-term rates of mitochondrial protein synthesis are increased in mouse skeletal muscle with high fat feeding regardless of insulin sensitizing treatment. Am J Physiol Endocrinol Metab 313:552-62. | Mouse | Skeletal muscle | Diabetes Obesity | |
De Velasco 2017 Br J Nutr | 2017 | de Velasco PC, Chicaybam G, Ramos-Filho DM, Dos Santos RMAR, Mairink C, Sardinha FLC, El-Bacha T, Galina A, Tavares-do-Carmo MDG (2017) Maternal intake of trans-unsaturated or interesterified fatty acids during pregnancy and lactation modifies mitochondrial bioenergetics in the liver of adult offspring in mice. Br J Nutr 118:41-52. | Mouse | Liver | ||
Cunha-de 2017 Thesis | 2017 | Cunha-de Padua MM (2017) Mecanismos citotóxicos da galactomanana de sementes de Schizolobium amazonicum e seus complexos com oxovanádio em células de hepatocarcinoma humano (HepG2) e efeito do silenciamento da enzima glucose-6-fosfato isomerase (GPI) na sobrevivência de células de adenocarcinoma de cólon humano (LS174T). Doctoral Thesis p160. | Human | Liver Other cell lines | Hypoxia | Cancer |
Boudoures 2017 Thesis | 2017 | Boudoures AL (2017) Mitochondrial damage accumulation in oocytes – a potential link between maternal obesity and increased cardiometabolic disease risk in offspring. PhD Thesis p179. | Mouse | Heart | Cardiovascular | |
Ljones 2017 PLOS ONE | 2017 | Ljones K, Ness HO, Solvang-Garten K, Gaustad SE, Andre Høydal M (2017) Acute exhaustive aerobic exercise training impair cardiomyocyte function and calcium handling in Sprague-Dawley rats. PLOS ONE 12:e0173449. | Rat | Heart | ||
Ounpuu 2017 Biochim Biophys Acta | 2017 | Ounpuu L, Klepinin A, Pook M, Teino I, Peet N, Paju K, Tepp K, Chekulayev V, Shevchuk I, Koks S, Maimets T, Kaambre T (2017) 2102Ep embryonal carcinoma cells have compromised respiration and shifted bioenergetic profile distinct from H9 human embryonic stem cells. Biochim Biophys Acta 1861:2146-54. | Human | Stem cells | Cancer | |
White 2017 Sci Rep | 2017 | White SH, Warren LK, Li C, Wohlgemuth SE (2017) Submaximal exercise training improves mitochondrial efficiency in the gluteus medius but not in the triceps brachii of young equine athletes. Sci Rep 7:14389. | Horse | Skeletal muscle | ||
Dahlke 2017 Glob Chang Biol | 2017 | Dahlke FT, Leo E, Mark FC, Pörtner HO, Bickmeyer U, Frickenhaus S, Storch D (2017) Effects of ocean acidification increase embryonic sensitivity to thermal extremes in Atlantic cod, Gadus morhua. Glob Chang Biol 23(4):1499-1510. | Fishes | Temperature | ||
Campos 2017 Autophagy | 2017 | Campos JC, Queliconi BB, Bozi LHM, Bechara LRG, Dourado PMM, Andres AM, Jannig PR, Gomes KMS, Zambelli VO, Rocha-Resende C, Guatimosim S, Brum PC, Mochly-Rosen D, Gottlieb RA, Kowaltowski AJ, Ferreira JCB (2017) Exercise reestablishes autophagic flux and mitochondrial quality control in heart failure. Autophagy 13:1304-317. | Rat | Heart | Permeability transition | Cardiovascular |
Tegelberg 2017 Orphanet J Rare Dis | 2017 | Tegelberg S, Tomašić N, Kallijärvi J, Purhonen J, Elmér E, Lindberg E, Nord DG, Soller M, Lesko N, Wedell A, Bruhn H, Freyer C, Stranneheim H, Wibom R, Nennesmo I, Wredenberg A, Eklund EA, Fellman V (2017) Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model. Orphanet J Rare Dis 12:73. | Human Mouse | Blood cells Platelet | Other | |
Crouch 2017 PLOS ONE | 2017 | Crouch ML, Knowels G, Stuppard R, Ericson NG, Bielas JH, Marcinek DJ, Syrjala KL (2017) Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects. PLOS ONE 12:e0181086. | Mouse | Skeletal muscle | Cancer | |
Jespersen 2017 J Physiol | 2017 | Jespersen NR, Yokota T, Støttrup NB, Bergdahl A, Paelestik KB, Povlsen JA, Dela F, Bøtker HE (2017) Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia-reperfusion. J Physiol 595:3765-80. | Rat | Heart | Ischemia-reperfusion Oxidative stress;RONS | |
Gabriel 2017 Thesis | 2017 | Gabriel C (2017) Avaliação da função mitocondrial em idosos institucionalizados com e sem Doença de Alzheimer. Dissertation p55. | Human | Lymphocyte | Oxidative stress;RONS | Alzheimer's |
Permer 2017 Bachelor Thesis | 2017 | Permer M (2017) Respirometrische Charakterisierung kryopräservierter HEK 239T Zellen. Bachelor Thesis 1-56. | Human | Other cell lines HEK | Cryopreservation | |
Porras 2017 Stem Cells | 2017 | Porras DP, Abbaszadeh M, Bhattacharya D, D'Souza NC, Edjiu NR, Perry CG, Scimè A (2017) p107 determines a metabolic checkpoint required for adipocyte lineage fates. Stem Cells 35:1378-91. | Mouse | Fat Fibroblast | ||
Fink 2017 Am J Physiol Cell Physiol | 2017 | Fink BD, Bai F, Yu L, Sivitz WI (2017) Regulation of ATP production: dependence on calcium concentration and respiratory state. Am J Physiol Cell Physiol 313:C146-53. | Mouse | Skeletal muscle | ||
Mueller 2017 Orphanet J Rare Dis | 2017 | Mueller SM, Gehrig SM, Petersen JA, Frese S, Mihaylova V, Ligon-Auer M, Khmara N, Nuoffer JM, Schaller A, Lundby C, Toigo M, Jung HH (2017) Effects of endurance training on skeletal muscle mitochondrial function in Huntington disease patients. Orphanet J Rare Dis 12:184. | Human | Skeletal muscle | Neurodegenerative | |
Westerlund 2017 Pediatr Res | 2017 | Westerlund E, Marelsson SE, Ehinger JK, Sjövall F, Morota S, Åsander Frostner E, Oldfors A, Darin N, Lundgren J, Hansson MJ, Fellman V, Elmér E (2017) Oxygen consumption in platelets as an adjunct diagnostic method for pediatric mitochondrial disease. Pediatr Res 83:455-65. | Human | Platelet Blood cells | Mitochondrial disease | |
Wolff 2017 Thesis | 2017 | Wolff C (2017) Impact of lipid metabolism on skeletal muscle mitochondrial function in type 2 diabetes mellitus patients. Dissertation p68. | Horse Human | Skeletal muscle | Diabetes Obesity | |
Sharaf 2017 Aquat Toxicol | 2017 | Sharaf MS, Stevens D, Kamunde C (2017) Zinc and calcium alter the relationship between mitochondrial respiration, ROS and membrane potential in rainbow trout (Oncorhynchus mykiss) liver mitochondria. Aquat Toxicol 189:170-83. | Fishes | Liver | ||
Dent 2017 Mol Metab | 2017 | Dent JR, Martins VF, Svensson K, LaBarge SA, Schlenk NC, Esparza MC, Buckner EH, Meyer GA, Hamilton DL, Schenk S, Philp A (2017) Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation. Mol Metab 6:1574-84. | Mouse | Skeletal muscle | ||
Ramirez 2017 Cell Metab | 2017 | Ramírez S, Gómez-Valadés AG, Schneeberger M, Varela L, Haddad-Tóvolli R, Altirriba J, Noguera E, Drougard A, Flores-Martínez Á, Imbernón M, Chivite I, Pozo M, Vidal-Itriago A, Garcia A, Cervantes S, Gasa R, Nogueiras R, Gama-Pérez P, Garcia-Roves PM, Cano DA, Knauf C, Servitja JM, Horvath TL, Gomis R, Zorzano A, Claret M (2017) Mitochondrial dynamics mediated by mitofusin 1 is required for POMC neuron glucose-sensing and insulin release control. Cell Metab 25:1390-9. | Mouse | Nervous system | ||
Sobotka 2017 Thesis | 2017 | Sobotka O (2017) Pharmacological and metabolic influence on liver mitochondrial functions. PhD Thesis p127. | Mouse Rat | Liver | ||
Cavalcanti-de-Albuquerque 2017 Mol Neurobiol | 2017 | Cavalcanti-de-Albuquerque JP, de Souza Ferreira E, de Carvalho DP, Galina A (2017) Mitochondria-bound hexokinase (mt-HK) activity differ in cortical and hypothalamic synaptosomes: differential role of mt-HK in H2O2 depuration. Mol Neurobiol 55:5889-5900. | Rat | Nervous system | ||
Carraro 2017 Mol Cell Endocrinol | 2017 | Carraro RS, Souza GF, Solon C, Razolli DS, Chausse B, Barbizan R, Victorio SC, Velloso LA (2017) Hypothalamic mitochondrial abnormalities occur downstream of inflammation in diet-induced obesity. Mol Cell Endocrinol 460:238-45. | Mouse | Nervous system | Obesity | |
Victor 2017 Thesis | 2017 | Victor L (2017) Investigating the possible cytoprotective effects of melatonin isomer against simulated ischemic injury. Master's Thesis 76. | Rat | Fibroblast | Ischemia-reperfusion | |
Selwood 2017 US Patent | 2017 | Selwood DL, Baker D, Szabadkai G, Duchen MR, Hill JM, Warne JND (2017) Quinolium conjugates of cyclosporin. US Patent US20170349632 A1. | Mouse | Liver | Ischemia-reperfusion | |
Haegler 2017 PLOS ONE | 2017 | Haegler P, Grünig D, Berger B, Terracciano L, Krähenbühl S, Bouitbir J (2017) Hepatic effects of pharmacological doses of hydroxy-cobalamin[c-lactam] in mice. PLOS ONE 12:e0171026. | Mouse | Liver | ||
Correa 2017 Crit Care | 2017 | Corrêa TD, Pereira AJ, Brandt S, Vuda M, Djafarzadeh S, Takala J, Jakob SM (2017) Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis. Crit Care 21:105. | Pig | Nervous system | Sepsis | |
Tueller 2017 Biochem Biophys Res Commun | 2017 | Tueller DJ, Harley JS, Hancock CR (2017) Effects of curcumin and ursolic acid on the mitochondrial coupling efficiency and hydrogen peroxide emission of intact skeletal myoblasts. Biochem Biophys Res Commun 492:368-72. | Skeletal muscle | Oxidative stress;RONS | ||
Wen 2017 Antioxid Redox Signal | 2017 | Wen JJ, Porter C, Garg NJ. (2017) Inhibition of NFE2L2-Antioxidant Response Element Pathway by Mitochondrial Reactive Oxygen Species Contributes to Development of Cardiomyopathy and Left Ventricular Dysfunction in Chagas Disease. Antioxid Redox Signal. 27(9):550-566. | Mouse | Heart | Oxidative stress;RONS | Infectious Myopathy |
Komlodi 2017 Neuropharmacology | 2017 | Komlódi T, Tretter L (2017) Methylene blue stimulates substrate-level phosphorylation catalysed by succinyl-CoA ligase in the citric acid cycle. Neuropharmacology 123:287-98. | Guinea pig | Nervous system | Neurodegenerative | |
Cardoso 2017 Biochim Biophys Acta | 2017 | Cardoso GMF, Pletsch JT, Parmeggiani B, Grings M, Glanzel NM, Bobermin LD, Amaral AU, Wajner M, Leipnitz G (2017) Bioenergetics dysfunction, mitochondrial permeability transition pore opening and lipid peroxidation induced by hydrogen sulfide as relevant pathomechanisms underlying the neurological dysfunction characteristic of ethylmalonic encephalopathy. Biochim Biophys Acta 1863:2192-2201. | Rat | Nervous system | Permeability transition | Other |
Min 2017 Skelet Muscle | 2017 | Min K, Lawan A, Bennett AM (2017) Loss of MKP-5 promotes myofiber survival by activating STAT3/Bcl-2 signaling during regenerative myogenesis. Skelet Muscle 7:21. | Mouse | Skeletal muscle | ||
Volani 2017 Metallomics | 2017 | Volani C, Doerrier C, Demetz E, Haschka D, Paglia G, Lavdas AA, Gnaiger E, Weiss G (2017) Dietary iron loading negatively affects liver mitochondrial function. Metallomics 9:1634-44. | Mouse | Liver | ||
Lores-Arnaiz 2017 J Neurochem | 2017 | Lores-Arnaiz S, Karadayian AG, Gutnisky A, Rodríguez de Lores Arnaiz G (2017) The low affinity neurotensin receptor antagonist levocabastine impairs brain nitric oxide synthesis and mitochondrial function by independent mechanisms. J Neurochem 143:684-96. | Rat | Nervous system | ||
Kyhl 2017 Peptides | 2017 | Kyhl K, Lønborg J, Hartmann B, Kissow H, Poulsen SS, Ali HE, Kjær A, Dela F, Engstrøm T, Treiman M (2017) Lack of effect of prolonged treatment with liraglutide on cardiac remodeling in rats after acute myocardial infarction. Peptides 93:1-12. | Rat | Heart | Cardiovascular Myopathy | |
Mahalingam 2017 J Physiol | 2017 | Mahalingam S, McClelland GB, Scott GR (2017) Evolved changes in the intracellular distribution and physiology of muscle mitochondria in high-altitude native deer mice. J Physiol 595:4785-801. | Mouse | Skeletal muscle | Hypoxia | |
Elmer 2017 US Patent | 2017 | Elmer E, Hansson MJ, Ehinger JK, Piel S, Moss S (2017) Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex I-related impairment of mitochondrial oxidative phosphorylation. US Patent US20170100359 A1. | Human | Heart Blood cells Fibroblast Macrophage-derived Platelet | ||
Calcutt 2017 J Clin Invest | 2017 | Calcutt NA, Smith DR, Frizzi K, Sabbir MG, Chowdhury SK, Mixcoatl-Zecuatl T, Saleh A, Muttalib N, Van der Ploeg R, Ochoa J, Gopaul A, Tessler L, Wess J, Jolivalt CG, Fernyhough P (2017) Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy. J Clin Invest 127:608-22. | Rat | Nervous system | Diabetes Neurodegenerative | |
Perks 2017 Sci Adv | 2017 | Perks KL, Ferreira N, Richman TR, Ermer JA, Kuznetsova I, Shearwood AJ, Lee RG, Viola HM, Johnstone VPA, Matthews V, Hool LC, Rackham O, Filipovska A (2017) Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv 3:e1700677. | Mouse | Heart Liver | Obesity | |
Cecatto 2017 Neurochem Int | 2017 | Cecatto C, Amaral AU, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Gonçalves AM, Vargas CR, Wajner M (2017) Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria. Neurochem Int 108:133-45. | Rat | Nervous system Liver | Permeability transition Oxidative stress;RONS | Other |
Vigueira 2017 Exp Physiol | 2017 | Vigueira PA, McCommis KS, Hodges WT, Schweitzer GG, Cole SL, Oonthonpan L, Taylor EB, McDonald WG, Kletzien RF, Colca JR, Finck BN (2017) The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism. Exp Physiol 102:985-99. | Human | Kidney HEK | Obesity | |
Boutant 2017 EMBO J | 2017 | Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cantó C (2017) Mfn2 is critical for brown adipose tissue thermogenic function. EMBO J 36:1543-58. | Mouse | Fat Fibroblast | ||
Mathers 2017 J Comp Physiol B | 2017 | Mathers KE, McFarlane SV, Zhao L, Staples JF (2017) Regulation of mitochondrial metabolism during hibernation by reversible suppression of electron transport system enzymes. J Comp Physiol B 187:227-34. | Other mammals | Liver | Temperature | |
Duicu 2017 Can J Physiol Pharmacol | 2017 | Duicu OM, Privistirescu A, Wolf A, Petruş A, Dănilă MD, Raţiu CD, Muntean DM, Sturza A (2017) Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts. Can J Physiol Pharmacol 95:1376-82. | Rat | Heart | Diabetes Myopathy | |
Galambo 2017 Thesis | 2017 | Galambo D (2017) The effect of cardiolipin on vascular smooth muscle cell dedifferentiation, function, and mitochondrial respiration. Master's Thesis p.90. | Mouse | Endothelial;epithelial;mesothelial cell | Cardiovascular | |
Friederich 2017 Hum Mol Genet | 2017 | Friederich MW, Erdogan AJ, Coughlin CR 2nd, Elos MT, Jiang H, O'Rourke CP, Lovell MA, Wartchow E, Gowan K, Chatfield KC, Chick WS, Spector EB, Van Hove JLK, Riemer J (2017) Mutations in the accessory subunit NDUFB10 result in isolated complex I deficiency and illustrate the critical role of intermembrane space import for complex I holoenzyme assembly. Hum Mol Genet 26:702-16. | Human | Fibroblast | Myopathy | |
Pfeiffer 2017 Free Radic Biol Med | 2017 | Pfeiffer A, Schneider J, Bueno D, Dolga A, Voss TD, Lewerenz J, Wüllner V, Methner A (2017) Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity. Free Radic Biol Med 112:350-9. | Mouse | Fibroblast | Oxidative stress;RONS | |
Asseburg 2017 Thesis | 2017 | Asseburg H (2017) Untersuchungen zur nutritiven Prävention der Neurodegeneration – Wirkungen von Trauben- und Olivenpolyphenolen auf die mitochondriale und kognitive Dysfunktion bei der Gehirnalterung und Alzheimer-Erkrankung. Dissertation p296. | Mouse Rat | Nervous system Other cell lines | Aging;senescence Alzheimer's | |
Sivitz 2017 Neuromethods | 2017 | Sivitz WI (2017) Techniques to investigate bioenergetics of mitochondria. In: Strack S, Usachev Y (eds) Techniques to investigate mitochondrial function in neurons. Neuromethods 123:67-94. Humana Press, New York. https://doi.org/10.1007/978-1-4939-6890-9_4 | ||||
Makrecka-Kuka 2017 Toxicol Lett | 2017 | Makrecka-Kuka M, Volska K, Antone U, Vilskersts R, Grinberga S, Bandere D, Liepinsh E, Dambrova M (2017) Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria. Toxicol Lett 267:32-8. | Mouse | Heart | ||
Kake 2017 J Therm Biol | 2017 | Kake Guena SA, Touisse K, Warren BE, Scott KY, Dufresne F, Blier PU, Lemieux H (2017) Temperature-related differences in mitochondrial function among clones of the cladoceran Daphnia pulex. J Therm Biol 69:23-31. | Crustaceans | Temperature | ||
Zholobenko 2017 PLOS ONE | 2017 | Zholobenko AV, Mouithys-Mickalad A, Dostal Z, Serteyn D, Modriansky M (2017) On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells. PLOS ONE 12:e0185691. | Rat | Heart | Hypoxia | |
Sansone 2017 Proc Natl Acad Sci U S A | 2017 | Sansone P, Savini C, Kurelac I, Chang Q, Amato LB, Strillacci A, Stepanova A, Iommarini L, Mastroleo C, Daly L, Galkin A, Thakur BK, Soplop N, Uryu K, Hoshino A, Norton L, Bonafé M, Cricca M, Gasparre G, Lyden D, Bromberg J (2017) Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer. Proc Natl Acad Sci U S A 114:E9066-75. | Human | Cancer | ||
Napa 2017 Int J Dent | 2017 | Napa K, Baeder AC, Witt JE, Rayburn ST, Miller MG, Dallon BW, Gibbs JL, Wilcox SH, Winden DR, Smith JH, Reynolds PR, Bikman BT (2017) LPS from P. gingivalis negatively alters gingival cell mitochondrial bioenergetics. Int J Dent 2017:2697210. | Human | Endothelial;epithelial;mesothelial cell | ||
Braz-Mota 2017 Thesis | 2017 | Braz Mota S (2017) Estudo comparativo da toxicidade e dos mecanismos de ação tóxica de nanopartículas de cobre e cobre em duas espécies de peixes da Amazônia: Apistogramma agassizii e Paracheirodon axelrodi. Dissertation p.78. | Fishes | Lung;gill | ||
Hartmann 2017 Crit Care Med | 2017 | Hartmann C, Loconte M, Antonucci E, Holzhauser M, Hölle T, Katzsch D, Merz T, McCook O, Wachter U, Vogt JA, Hoffmann A, Wepler M, Gröger M, Matejovic M, Calzia E, Georgieff M, Asfar P, Radermacher P, Nussbaum BL (2017) Effects of hyperoxia during resuscitation from hemorrhagic shock in swine with preexisting coronary artery disease. Crit Care Med 45:e1270-9. | Pig | Heart Liver Kidney | Oxidative stress;RONS | Other |
Buck 2017 PLOS ONE | 2017 | Buck E, Zügel M, Schumann U, Merz T, Gumpp AM, Witting A, Steinacker JM, Landwehrmeyer GB, Weydt P, Calzia E, Lindenberg KS (2017) High-resolution respirometry of fine-needle muscle biopsies in pre-manifest Huntington's disease expansion mutation carriers shows normal mitochondrial respiratory function. PLOS ONE 12:e0175248. | Human Mouse | Heart Skeletal muscle Nervous system Liver | Neurodegenerative | |
Rekuviene 2017 Data Brief | 2017 | Rekuviene E, Ivanoviene L, Borutaite V, Morkuniene R (2017) Data on effects of rotenone on calcium retention capacity, respiration and activities of respiratory chain complexes I and II in isolated rat brain mitochondria. Data Brief 13:707-12. | Rat | Nervous system | Cryopreservation Ischemia-reperfusion | |
Desprat 2017 Comp Biochem Physiol A Mol Integr Physiol | 2017 | Desprat JL, Teulier L, Puijalon S, Dumet A, Romestaing C, Tattersall GJ, Lengagne T, Mondy N (2017) Doping for sex: Bad for mitochondrial performances? Case of testosterone supplemented Hyla arborea during the courtship period. Comp Biochem Physiol A Mol Integr Physiol 209:74-83. | Amphibians | Skeletal muscle | ||
Han 2017 Invest Ophthalmol Vis Sci | 2017 | Han WH, Gotzmann J, Kuny S, Huang H, Chan CB, Lemieux H, Sauvé Y (2017) Modifications in retinal mitochondrial respiration precede type 2 diabetes and protracted microvascular retinopathy. Invest Ophthalmol Vis Sci 58:3826-39. | Rat | Nervous system | Diabetes | |
Yang 2017 Cell Death Dis | 2017 | Yang N, Weinfeld M, Lemieux H, Montpetit B, Goping IS (2017) Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis. Cell Death Dis 8:e2587. | Saccharomyces cerevisiae Human | Lymphocyte | Cell death | Cancer |
Kenny 2017 Diabetologia | 2017 | Kenny HC, Rudwill F, Breen L, Salanova M, Blottner D, Heise T, Heer M, Blanc S, O'Gorman DJ (2017) Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistance. Diabetologia 60:1491-501. | Human | Skeletal muscle | Diabetes | |
Scheede-Bergdahl 2017 Can J Physiol Pharmacol | 2017 | Scheede-Bergdahl C, Bergdahl A (2017) Adaptation of mitochondrial expression and ATP production in dedifferentiating vascular smooth muscle cells. Can J Physiol Pharmacol 95:1473-9. | Mouse | Endothelial;epithelial;mesothelial cell | Cardiovascular | |
Horscroft 2017 Proc Natl Acad Sci U S A | 2017 | Horscroft JA, Kotwica AO, Laner V, West JA, Hennis PJ, Levett DZH, Howard DJ, Fernandez BO, Burgess SL, Ament Z, Gilbert-Kawai ET, Vercueil A, Landis BD, Mitchell K, Mythen MG, Branco C, Johnson RS, Feelisch M, Montgomery HE, Griffin JL, Grocott MPW, Gnaiger E, Martin DS, Murray AJ (2017) Metabolic basis to Sherpa altitude adaptation. Proc Natl Acad Sci U S A 114:6382–7. https://doi.org/10.1073/pnas.1700527114 | Human | Skeletal muscle | Oxidative stress;RONS Hypoxia | |
Yeh 2017 Aquat Toxicol | 2017 | Yeh A, Marcinek DJ, Meador JP, Gallagher EP (2017) Effect of contaminants of emerging concern on liver mitochondrial function in Chinook salmon. Aquat Toxicol 190:21-31. | Fishes | Liver | ||
Shen 2017 Thesis | 2017 | Shen NY (2017) Characterizing protein arginine methyltransferase expression, localization, and function during myogenesis. Master's Thesis p106. | Mouse | Skeletal muscle | ||
Lopez 2017 PLOS ONE | 2017 | López A, Ortiz F, Doerrier C, Venegas C, Fernández-Ortiz M, Aranda P, Díaz-Casado ME, Fernández-Gil B, Barriocanal-Casado E, Escames G, López L, Acuña-Castroviejo D (2017) Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases. PLOS ONE 12:e0183090. | Mouse | Parkinson's | ||
Goedecke 2017 JMIR Res Protoc | 2017 | Goedecke JH, Mendham AE, Clamp L, Nono Nankam PA, Fortuin-de Smidt MC, Phiri L, Micklesfield LK, Keswell D, Woudberg NJ, Lecour S, Alhamud A, Kaba M, Lutomia FM, van Jaarsveld PJ, de Villiers A, Kahn SE, Chorell E, Hauksson J, Olsson T (2017) An exercise intervention to unravel the mechanisms underlying insulin resistance in a cohort of black South African women: Protocol for a randomized controlled trial. JMIR Res Protoc 03/10/2017:9098. | Human | Skeletal muscle Fat | Diabetes Obesity | |
Nemeth 2017 Thesis | 2017 | Németh B (2017) The effect of itaconic acid on mitochondrial substrate-level phosphorylation. PhD Thesis p84. | Mouse | Liver | ||
Varga 2017 Inflammopharmacology | 2017 | Varga G, Ugocsai M, Hartmann P, Lajkó N, Molnár R, Szűcs S, Jász DK, Érces D, Ghyczy M, Tóth G, Boros M (2017) Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis. Inflammopharmacology 26:261-71. | Rat | Liver | Infectious Other | |
Djafarzadeh 2017b J Vis Exp | 2017 | Djafarzadeh S, Jakob SM (2017) Isolation of intact mitochondria from skeletal muscle by differential centrifugation for High-Resolution Respirometry measurements. J Vis Exp doi: 10.3791/55251. | Skeletal muscle | |||
Mantilla 2017 PLOS Pathog | 2017 | Mantilla BS, Marchese L, Casas-Sánchez A, Dyer NA, Ejeh N, Biran M, Bringaud F, Lehane MJ, Acosta-Serrano A, Silber AM (2017) Proline metabolism is essential for Trypanosoma brucei brucei survival in the tsetse vector. PLOS Pathog 13:e1006158. | Protists | |||
Zhang 2017 J Am Heart Assoc | 2017 | Zhang X, Zhang Z, Zhao Y, Jiang N, Qiu J, Yang Y, Li J, Liang X, Wang X, Tse G, Li G, Liu T (2017) Alogliptin, a dipeptidyl peptidase-4 inhibitor, alleviates atrial remodeling and improves mitochondrial function and biogenesis in diabetic rabbits. J Am Heart Assoc 6:e005945. | Rabbit | Heart | Diabetes | |
Yu 2017 Free Radic Biol Med | 2017 | Yu Y, Wang L, Delguste F, Durand A, Guilbaud A, Rousselin C, Schmidt AM, Tessier F, Boulanger E, Neviere R (2017) Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway. Free Radic Biol Med 112:397-410. | Mouse | Heart | Diabetes | |
Krycer 2017 Biochem Biophys Res Commun | 2017 | Krycer JR, Fisher-Wellman KH, Fazakerley DJ, Muoio DM, James DE (2017) Bicarbonate alters cellular responses in respiration assays. Biochem Biophys Res Commun 489:399-403. | Mouse | Liver Fat | ||
Honrath 2017 Cell Death Differ | 2017 | Honrath B, Matschke L, Meyer T, Magerhans L, Perocchi F, Ganjam GK, Zischka H, Krasel C, Gerding A, Bakker BM, Bünemann M, Strack S, Decher N, Culmsee C, Dolga AM (2017) SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake. Cell Death Differ 24:761-73. | Mouse | Nervous system Other cell lines | Neurodegenerative | |
Van Schaardenburgh 2017 J Transl Med | 2017 | van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson EJR (2017) Exercise in claudicants increase or decrease walking ability and the response relates to mitochondrial function. J Transl Med 15:130. | Human | Skeletal muscle | Ischemia-reperfusion | |
Uppala 2017 Biochem Biophys Res Commun | 2017 | Uppala R, Dudiak B, Beck ME, Bharathi SS, Zhang Y, Stolz DB, Goetzman ES (2017) Aspirin increases mitochondrial fatty acid oxidation. Biochem Biophys Res Commun 482:346-51. | Human Mouse | HEK Fibroblast | Other | |
Schoenfeld 2017 Neurochem Int | 2017 | Schönfeld P, Reiser G (2017) Brain energy metabolism spurns fatty acids as fuel due to their inherent mitotoxicity and potential capacity to unleash neurodegeneration. Neurochem Int 109:68-77. | Rat | Nervous system Liver | Neurodegenerative | |
Martins 2017 Thesis | 2017 | Martins WC (2017) Estudo do efeito protetor da atorvastatina e dos eventos iniciais da neurotoxicidade induzida pelo peptídeo β-amilóide (Aβ1-40) em camundongos. Doctoral Thesis p85. | Mouse | Nervous system | Alzheimer's | |
Bohanon 2017 Shock | 2017 | Bohanon FJ, Lopez ON, Herndon DN, Wang X, Bhattarai N, Ayadi AE, Prasai A, Jay JW, Rojas-Khalil Y, Toliver-Kinsky TE, Finnerty CC, Radhakrishnan RS, Porter C (2017) Burn trauma acutely increases the respiratory capacity and function of liver mitochondria. Shock 49:466-73. | Mouse | Liver | ||
Sidlauskas 2017 Neurosci Lett | 2017 | Sidlauskas K, Sidlauskiene R, Li N, Liobikas J (2017) 5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain. Neurosci Lett 639:207-14. | Rat | Nervous system Other cell lines | Oxidative stress;RONS | Cancer |
Kake-Guena 2017 J Therm Biol | 2017 | Kake-Guena SA, Touisse K, Warren BE, Scott KY, Blier PU, Lemieux H (2017) Temperature-related differences in mitochondrial function among clones of the cladoceran Daphnia pulex. J Therm Biol 69:23-31. | Crustaceans | Temperature | ||
Thomsen 2017 Neurobiol Aging | 2017 | Thomsen K, Yokota T, Hasan-Olive MM, Sherazi N, Fakouri NB, Desler C, Regnell CE, Larsen S, Rasmussen LJ, Dela F, Bergersen LH, Lauritzen M (2017) Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus. Neurobiol Aging 61:215-24. | Mouse | Nervous system | ||
Van den Berg 2017 Am J Respir Crit Care Med | 2017 | van den Berg M, Hooijman PE, Beishuizen A, de Waard MC, Paul MA, Hartemink KJ, van Hees HWH, Lawlor MW, Brocca L, Bottinelli R, Pellegrino MA, Stienen GJM, Heunks LMA, Wüst RCI, Ottenheijm CAC (2017) Diaphragm atrophy and weakness in the absence of mitochondrial dysfunction in the critically ill. Am J Respir Crit Care Med 196:1544-58. | Human | Skeletal muscle | Other | |
Miller 2017 PLOS ONE | 2017 | Miller B, Hamilton K, Boushel R, Williamson K, Laner V, Gnaiger E, Davis M (2017) Mitochondrial respiration in highly aerobic canines in the non-raced state and after a 1600-km sled dog race. PLOS ONE 12:e0174874. | Dog | Skeletal muscle | ||
Paech 2017 Arch Toxicol | 2017 | Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, Krähenbühl S, Maurer M (2017) Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072. Arch Toxicol 91:3647-62. | Human | Liver Other cell lines | ||
Kanaan 2017 Redox Biol | 2017 | Kanaan GN, Ichim B, Gharibeh L, Maharsy W, Patten DA, Xuan JY, Reunov A, Marshall P, Veinot J, Menzies K, Nemer M, Harper ME (2017) Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies. Redox Biol 14:509-21. | Mouse | Heart | ||
Da Silva 2017 Neurotox Res | 2017 | Da Silva JC, Amaral AU, Cecatto C, Wajner A, Dos Santos Godoy K, Ribeiro RT, de Mello Gonçalves A, Zanatta Â, da Rosa MS, Loureiro SO, Vargas CR, Leipnitz G, de Souza DOG, Wajner M (2017) α-Ketoadipic acid and α-aminoadipic acid cause disturbance of glutamatergic neurotransmission and induction of oxidative stress in vitro in brain of adolescent rats. Neurotox Res 32:276-90. | Rat | Nervous system | Oxidative stress;RONS | |
Lau 2017 Mol Biol Evol | 2017 | Lau GY, Mandic M, Richards JG (2017) Evolution of cytochrome c oxidase in hypoxia tolerant Sculpins (Cottidae, Actinopterygii). Mol Biol Evol 34:2153-62. | Fishes | Nervous system | Hypoxia | |
Ho 2017 Thesis | 2017 | Ho DH (2017) The role of MLQ protein in structure and function of mammalian ATP synthase. Master's Thesis p84. | Human | Kidney | ||
Busanello 2017 Front Pharmacol | 2017 | Busanello ENB, Marques AC, Lander N, de Oliveira DN, Catharino RR, Oliveira HCF, Vercesi AE (2017) Pravastatin chronic treatment sensitizes hypercholesterolemic mice muscle to mitochondrial permeability transition: protection by creatine or coenzyme Q10. Front Pharmacol 8:185. | Mouse | Skeletal muscle | Permeability transition | |
Neckar 2017 Clin Sci (Lond) | 2017 | Neckar J, Svatonova A, Weissova R, Drahota Z, Zajickova P, Brabcova I, Kolar D, Alanova P, Vasinova J, Silhavy J, Hlavackova M, Tauchmannova K, Milerova M, Ostadal B, Cervenka L, Zurmanova J, Kalous M, Novakova O, Novotny J, Pravenec M, Kolar F (2017) Selective replacement of mitochondrial DNA increases the cardioprotective effect of chronic continuous hypoxia in spontaneously hypertensive rats. Clin Sci (Lond) 131:865-81. | Rat | Heart | Permeability transition Hypoxia | Cardiovascular |
Testoni 2017 Cell Metab | 2017 | Testoni G, Duran J, García-Rocha M, Vilaplana F, Serrano AL, Sebastián D, López-Soldado I, Sullivan MA6, Slebe F, Vilaseca M, Muñoz-Cánoves P, Guinovart JJ (2017) Lack of glycogenin causes glycogen accumulation and muscle function impairment. Cell Metab 26:256-66. | Mouse | Skeletal muscle | ||
Schatton 2017 J Cell Biol | 2017 | Schatton D, Pla-Martin D, Marx MC, Hansen H, Mourier A, Nemazanyy I, Pessia A, Zentis P, Corona T, Kondylis V, Barth E, Schauss AC, Velagapudi V, Rugarli EI (2017) CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol 216:675-93. | Mouse | Liver | ||
Xiong 2017 J Am Heart Assoc | 2017 | Xiong S, Wang B, Lin S, Zhang H, Li Y, Wei X, Cui Y, Wei X, Lu Z, Gao P, Li L, Zhao Z, Liu D, Zhu Z (2017) Activation of transient receptor potential melastatin subtype 8 attenuates cold-induced hypertension through ameliorating vascular mitochondrial dysfunction. J Am Heart Assoc 6. pii: e005495. | Mouse | Endothelial;epithelial;mesothelial cell | Temperature | |
Cardinale 2017 Front Physiol | 2017 | Cardinale DA, Lilja M, Mandić M, Gustafsson T, Larsen FJ, Lundberg TR (2017) Resistance training with co-ingestion of anti-inflammatory drugs attenuates mitochondrial function. Front Physiol 8:1074. | Human | Skeletal muscle | ||
Nabben 2017 Am J Physiol Regul Integr Comp Physiol | 2017 | Nabben M, Schmitz JP, Ciapaite J, Le Clercq CM, van Riel NA, Haak HR, Nicolay K, de Coo IF, Smeets HJ, Praet SF, van Loon LJ, Prompers JJ (2017) Dietary nitrate does not reduce oxygen cost of exercise or improve muscle mitochondrial function in mitochondrial myopathy patients. Am J Physiol Regul Integr Comp Physiol 312:689-701. | Human | Skeletal muscle | Myopathy | |
Grassi 2017 J Appl Physiol (1985) | 2017 | Grassi B, Majerczak J, Bardi E, Buso A, Comelli M, Chlopicki S, Guzik M, Mavelli I, Nieckarz Z, Salvadego D, Tyrankiewicz U, Skórka T, Bottinelli R, Zoladz JA, Pellegrino MA (2017) Exercise training in Tgαq*44 mice during the progression of chronic heart failure: cardiac vs. peripheral (soleus muscle) impairments to oxidative metabolism. J Appl Physiol (1985) 123:326-36. | Mouse | Skeletal muscle | Cardiovascular | |
Derungs 2017 Mol Psychiatry | 2017 | Derungs R, Camici GG, Spescha RD, Welt T, Tackenberg C, Späni C, Wirth F, Grimm A, Eckert A, Nitsch RM, Kulic L (2017) Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease. Mol Psychiatry 22:605-14. | Mouse | Nervous system | Aging;senescence Alzheimer's | |
Emmett 2017 Nature | 2017 | Emmett MJ, Lim HW, Jager J, Richter HJ, Adlanmerini M, Peed LC, Briggs ER, Steger DJ, Ma T, Sims CA, Baur JA, Pei L, Won KJ, Seale P, Gerhart-Hines Z, Lazar MA (2017) Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge. Nature 546:544-8. | Mouse | Fat | Temperature | |
Xu 2017 Diabetes | 2017 | Xu D, Xu S, Kyaw AMM, Lim YC, Chia SY, Chee Siang DT, Alvarez-Dominguez JR, Chen P, Leow MK, Sun L (2017) RNA binding protein Ybx2 regulates RNA stability during cold-induced brown fat activation. Diabetes 66:2987-3000. | Mouse | Skeletal muscle | ||
Koning 2017 J Cereb Blood Flow Metab | 2017 | Koning G, Leverin AL, Nair S, Schwendimann L, Ek J, Carlsson Y, Gressens P, Thornton C, Wang X, Mallard C, Hagberg H (2017) Magnesium induces preconditioning of the neonatal brain via profound mitochondrial protection. J Cereb Blood Flow Metab 39:1038-55. | Rat | Ischemia-reperfusion Hypoxia | ||
Herledan 2017 Thesis | 2017 | Herledan G (2017) Le role de SRF au cours de l'atrophie du muscle squelettique adulte & dans les cellules satellites. Diploma Thesis p166. | Mouse | Skeletal muscle | ||
Park 2017 Metab Brain Dis | 2017 | Park HS, Cho HS, Kim TW (2017) Physical exercise promotes memory capability by enhancing hippocampal mitochondrial functions and inhibiting apoptosis in obesity-induced insulin resistance by high fat diet. Metab Brain Dis 33:283-92. | Mouse | Nervous system | Cell death | Diabetes |
Warren 2017 Metabolism | 2017 | Warren JL, Bulur S, Ovalle F, Windham ST, Gower BA, Fisher G (2017) Effects of acute hyperinsulinemia on skeletal muscle mitochondrial function, reactive oxygen species production, and metabolism in premenopausal women. Metabolism 77:1-12. | Human | Skeletal muscle | Diabetes | |
Van Schaardenburgh 2017 J Vasc Surg | 2017 | Van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson E (2017) Calf raise exercise increases walking performance in patients with intermittent claudication. J Vasc Surg 65:1473-82. | Human | Skeletal muscle | ||
Pecinova 2017 Oxid Med Cell Longev | 2017 | Pecinova A, Drahota Z, Kovalcikova J, Kovarova N, Pecina P, Alan L, Zima M, Houstek J, Mracek T (2017) Pleiotropic effects of biguanides on mitochondrial reactive oxygen species production. Oxid Med Cell Longev 7038603. | Rat | Fat | Oxidative stress;RONS | Diabetes |
Warren 2017 J Nutr Metab | 2017 | Warren JL, Gower BA, Hunter GR, Windham ST, Moellering DR, Fisher G (2017) Associations of mitochondrial fatty acid oxidation with body fat in premenopausal women. J Nutr Metab 2017:7832057. | Human | Skeletal muscle | Obesity | |
Lalia 2017 Aging (Albany NY) | 2017 | Lalia AZ, Dasari S, Robinson MM, Abid H, Morse DM, Klaus KA, Lanza IR (2017) Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults. Aging (Albany NY) 9:1096-1129. | Human | Skeletal muscle | Aging;senescence | |
Heim 2017 Am J Physiol Regul Integr Comp Physiol | 2017 | Heim AB, Chung D, Florant GL, Chicco AJ (2017) Tissue-specific seasonal changes in mitochondrial function of a mammalian hibernator. Am J Physiol Regul Integr Comp Physiol 313:R180-90. | Other mammals | Heart Skeletal muscle Liver Fat | ||
Dallon 2017 Biochem J | 2017 | Dallon BW, Parker BA, Hodson AE, Tippetts TS, Harrison ME, Appiah MMA, Witt JE, Gibbs JL, Gray HM, Sant TM, Bikman BT (2017) Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice. Biochem J 475:561-9. | Mouse | Skeletal muscle Fat | Diabetes | |
McFarlane 2017 Am J Physiol Regul Integr Comp Physiol | 2017 | McFarlane SV, Mathers KE, Staples JF (2017) Reversible temperature-dependent differences in brown adipose tissue respiration during torpor in a mammalian hibernator. Am J Physiol Regul Integr Comp Physiol 312:R434-42. | Other mammals | Fat | Temperature | |
Ladd 2017 Brain Res | 2017 | Ladd AC, Brohawn DG, Thomas RR, Keeney PM, Berr SS, Khan SM, Portell FR, Shakenov MZ, Antkowiak PF, Kundu B, Tustison N, Bennett JP (2017) RNA-seq analyses reveal that cervical spinal cords and anterior motor neurons from amyotrophic lateral sclerosis subjects show reduced expression of mitochondrial DNA-encoded respiratory genes, and rhTFAM may correct this respiratory deficiency. Brain Res 1667:74-83. | Rat | Nervous system | Neurodegenerative | |
Wu 2017 Sci Rep | 2017 | Wu LH, Chang SC, Fu TC, Huang CH, Wang JS (2017) High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep 7:4191. | Human | Blood cells Platelet | Hypoxia | |
Svensson 2017 Acta Physiol (Oxf) | 2017 | Svensson K, LaBarge SA, Martins VF, Schenk S (2017) Temporal overexpression of SIRT1 in skeletal muscle of adult mice does not improve insulin sensitivity or markers of mitochondrial biogenesis. Acta Physiol (Oxf) 221:193-203. | Mouse | Skeletal muscle | Diabetes | |
Wollenman 2017 PLOS ONE | 2017 | Wollenman LC, Vander Ploeg MR, Miller ML, Zhang Y, Bazil JN (2017) The effect of respiration buffer composition on mitochondrial metabolism and function. PLOS ONE 12:e0187523. | Guinea pig | Heart Liver | ||
Joergensen 2017 Physiol Rep | 2017 | Jørgensen W, Rud KA, Mortensen OH, Frandsen L, Grunnet N, Quistorff B (2017) Your mitochondria are what you eat: a high-fat or a high-sucrose diet eliminates metabolic flexibility in isolated mitochondria from rat skeletal muscle. Physiol Rep 5. pii: e13207. | Rat | Skeletal muscle | ||
Greggio 2017 Cell Metab | 2017 | Greggio C, Jha P, Kulkarni SS, Lagarrigue S, Broskey NT, Boutant M, Wang X, Alonso SC, Ofori E, Auwerx J, Cantó C, Amati F (2017) Enhanced respiratory chain supercomplex formation in response to exercise in human skeletal muscle. Cell Metab 25:301-11. | Human | Skeletal muscle | ||
De Moura 2017 Neurotox Res | 2017 | de Moura Alvorcem L, da Rosa MS, Glänzel NM, Parmeggiani B, Grings M, Schmitz F, Wyse ATS, Wajner M, Leipnitz G (2017) Disruption of energy transfer and redox status by sulfite in hippocampus, striatum, and cerebellum of developing rats. Neurotox Res 32:264-75. | Rat | Nervous system | ||
Broatch 2017 Am J Physiol Regul Integr Comp Physiol | 2017 | Broatch JR, Petersen A, Bishop DJ (2017) Cold-water immersion following sprint interval training does not alter endurance signaling pathways or training adaptations in human skeletal muscle. Am J Physiol Regul Integr Comp Physiol 313:R372-84. | Human | Skeletal muscle | ||
Lau 2017 Dissertation | 2017 | Lau G (2017) Adaptive variation of mitochondrial function in response to oxygen variability in intertidal sculpins (Cottidae, Actinopterygii). Dissertation p148. | Fishes | Nervous system | Hypoxia | |
De Carvalho 2017 Toxicol Research | 2017 | de Carvalho NR, Rodrigues NR, Macedo GE, Boligon AA, de Campos MM, Posser T, Cunha FAB, Coutinho HD, Klamt F, Bristot IJ, Merritt TJS, Franco JL (2017) Eugenia uniflora leaves essential oil promotes mitochondrial dysfunction in Drosophila melanogaster through the inhibition of oxidative phosphorylation. Toxicol Research 6:526-34 . | Drosophila | |||
Trewin 2017 PLOS ONE | 2017 | Trewin AJ, Levinger I, Parker L, Shaw CS, Serpiello FR, Anderson MJ, McConell GK, Hare DL, Stepto NK (2017) Acute exercise alters skeletal muscle mitochondrial respiration and H2O2 emission in response to hyperinsulinemic-euglycemic clamp in middle-aged obese men. PLOS ONE 12:e0188421. | Human | Skeletal muscle | Oxidative stress;RONS | Obesity |
Pamenter 2017 J Exp Biol | 2017 | Pamenter ME, Lau GY, Richards JG, Milsom WK (2017) Naked mole rat brain mitochondria electron transport system flux and H+ leak are reduced during acute hypoxia. J Exp Biol 221. | Other mammals | Nervous system | Hypoxia | |
Morrow 2017 Proc Natl Acad Sci U S A | 2017 | Morrow RM, Picard M, Derbeneva O, Leipzig J, McManus MJ, Gouspillou G, Barbat-Artigas S, Dos Santos C, Hepple RT, Murdock DG, Wallace DC (2017) Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity. Proc Natl Acad Sci U S A 114:2705-10. | Skeletal muscle | Diabetes | ||
Buso 2017 Thesis | 2017 | Buso A (2017) Mitochondrial oxidative phosphorylation plasticity/adaptation triggered by disturbances and stresses and targeted by therapies. PhD Thesis p110. | Mouse | Skeletal muscle | Aging;senescence | |
Lopez 2017 Sci Rep | 2017 | Lopez Sanchez MIG, Waugh HS, Tsatsanis A, Wong BX, Crowston JG, Duce JA, Trounce IA (2017) Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta. Sci Rep 7:9835. | Human | Alzheimer's Cancer | ||
Lemieux 2017 Sci Rep | 2017 | Lemieux H, Blier PU, Gnaiger E (2017) Remodeling pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in permeabilized fibers. Sci Rep 7:2840. doi:10.1038/s41598-017-02789-8 | Mouse | Heart | ||
Menezes-Filho 2017 Free Radic Biol Med | 2017 | Menezes-Filho SL, Amigo I, Prado FM, Ferreira NC, Koike MK, Pinto IFD, Miyamoto S, Montero EFS, Medeiros MHG, Kowaltowski AJ (2017) Caloric restriction protects livers from ischemia/reperfusion damage by preventing Ca2+-induced mitochondrial permeability transition. Free Radic Biol Med 110:219-27. | Mouse | Liver | Ischemia-reperfusion Permeability transition | |
MiPNet21.14 Reference sample HRR | 2016-10-19 | Development of a reference sample for HRR. | Human | HEK | Cryopreservation | |
MiPNet21.12 Comparison mt respiration media | 2016-10-18 | O2k-MultiSensor: Mitochondrial respiration media for HRR and simultaneous O2k-Fluorometry. | Human | HEK | ||
MiPNet21.13 Comparison mt-preparations | 2016-10-18 | O2k-Protocols: Mitochondrial preparations for HRR. | Mouse | Heart | ||
MiPNet21.07 MitoFit DatLab PT | 2016-07-20 | MitoFit DatLab proficiency test. | Human | |||
Fisar 2016 Curr Alzheimer Res | 2016 | Fišar Z, Hroudová J, Hansíková H, Spáčilová J, Lelková P, Wenchich L, Jirák R, Zvěřová M, Zeman J, Martásek P, Raboch J (2016) Mitochondrial respiration in the platelets of patients with Alzheimer's disease. Curr Alzheimer Res 13:930-41. | Human | Blood cells Platelet | Alzheimer's | |
Radovic 2016 Diabetologia | 2016 | Radović B, Vujić N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J, Wegscheider M, Tomin T, Birner-Gruenberger R, Schittmayer M, Groschner L, Magnes C, Diwoky C, Frank S, Steyrer E, Du H, Graier WF, Madl T, Kratky D (2016) Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice. Diabetologia 59:1743-52. | Mouse | Liver | ||
Kacso 2016 Biochem J | 2016 | Kacso G, Ravasz D, Doczi J, Németh B, Madgar O, Saada A, Ilin P, Miller C, Ostergaard E, Iordanov I, Adams D, Vargedo Z, Araki M, Araki K, Nakahara M, Ito H, Gál A, Molnár MJ, Nagy Z, Patocs A, Adam-Vizi V, Chinopoulos C (2016) Two transgenic mouse models for β-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations. Biochem J 473:3463-85. | Mouse | Heart Nervous system Liver | ||
Schiffer 2016 Am J Physiol Cell Physiol | 2016 | Schiffer TA, Peleli M, Sundqvist ML, Ekblom B, Lundberg JO, Weitzberg E, Larsen FJ (2016) Control of human energy expenditure by cytochrome c oxidase subunit IV-2. Am J Physiol Cell Physiol 311:C452-61. | Human | Skeletal muscle HEK | Oxidative stress;RONS Hypoxia | |
Vinnakota 2016a Biophys J | 2016 | Vinnakota KC, Bazil JN, Van den Bergh F, Wiseman RW, Beard DA (2016) Feedback regulation and time hierarchy of oxidative phosphorylation in cardiac mitochondria. Biophys J 110:972-80. | Rat | Heart | ||
Tyrrell 2016 Redox Biol | 2016 | Tyrrell DJ, Bharadwaj MS, Jorgensen MJ, Register TC, Molina AJ (2016) Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial health. Redox Biol 10:65-77. https://doi.org/10.1016/j.redox.2016.09.009 | Other mammals Human | Skeletal muscle Blood cells Platelet | ||
Ruas 2016 PLOS ONE | 2016 | Ruas JS, Siqueira-Santos ES, Amigo I, Rodrigues-Silva E, Kowaltowski AJ, Castilho RF (2016) Underestimation of the maximal capacity of the mitochondrial electron transport system in oligomycin-treated cells. PLOS ONE 11:e0150967. | Human Rat | Nervous system Genital Other cell lines | Cancer | |
Gomez 2016 Thesis | 2016 | Gomez CR (2016) Mitochondrial responses to anoxia exposure in red eared sliders (Trachemys scripta). Master's Thesis p102. | Reptiles | Heart Nervous system | Oxidative stress;RONS | |
Porter 2016 J Burn Care Res | 2016 | Porter C, Herndon DN, Børsheim E, Bhattarai N, Chao T, Reidy PT, Rasmussen BB, Andersen CR, Suman OE, Sidossis LS. (2016) Long-Term Skeletal Muscle Mitochondrial Dysfunction is Associated with Hypermetabolism in Severely Burned Children.. J Burn Care Res 37(1):53-63. | Skeletal muscle | Other | ||
Tretter 2016 Biochim Biophys Acta | 2016 | Tretter L, Patocs A, Chinopoulos C (2016) Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis. https://doi.org/10.1016/j.bbabio.2016.03.012 | Oxidative stress;RONS | Cancer | ||
Hagl 2016 Nutr Neurosci | 2016 | Hagl S, Berressem D, Grewal R, Grebenstein N, Frank J, Eckert GP (2016) Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice. Nutr Neurosci 19:1-10. | Mouse | Nervous system | Aging;senescence Neurodegenerative | |
Krischek 2016 Mol Reprod Dev | 2016 | Krischek C, Janisch S, Naraballobh W, Brunner R, Wimmers K, Wicke M (2016) Altered incubation temperatures between embryonic Days 7 and 13 influence the weights and the mitochondrial respiratory and enzyme activities in breast and leg muscles of broiler embryos. Mol Reprod Dev 83:71-8. | Chicken | Skeletal muscle | Temperature | |
Sadhukhan 2016 Proc Natl Acad Sci U S A | 2016 | Sadhukhan S, Liu X, Ryu D, Nelson OD, Stupinski JA, Li Z, Chen W, Zhang S, Weiss RS, Locasale JW, Auwerx J, Lin H (2016) Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function. Proc Natl Acad Sci U S A 113:4320-5. | Mouse | Heart | ||
Miotto 2016 Biochem J | 2016 | Miotto PM, Holloway GP (2016) In the absence of phosphate shuttling, exercise reveals the in vivo importance of creatine-independent mitochondrial ADP transport. Biochem J 473:2831-43. | Mouse | Skeletal muscle | ||
Strifler 2016b PLOS ONE | 2016 | Strifler G, Tuboly E, Görbe A, Boros M, Pécz D, Hartmann P (2016) Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine. PLOS ONE 11:e0166682. | Rat | Liver | Ischemia-reperfusion | |
Pamenter 2016 Biol Lett | 2016 | Pamenter ME, Gomez CR, Richards JG, Milsom WK (2016) Mitochondrial responses to prolonged anoxia in brain of red-eared slider turtles. Biol Lett 12. pii: 20150797. | Reptiles | Nervous system | Oxidative stress;RONS | |
Yavari 2016 Cell Metab | 2016 | Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martinez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Toth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H (2016) Chronic activation of γ2 AMPK induces obesity and reduces β cell function. Cell Metab 23:821-36. | Mouse | Nervous system | Aging;senescence Obesity | |
Anand 2016 PLOS ONE | 2016 | Anand R, Strecker V, Urbach J, Wittig I, Reichert AS (2016) Mic13 is essential for formation of crista junctions in mammalian cells. PLOS ONE 11:e0160258. | HEK | |||
Moll 2016 bioRxiv | 2016 | Moll CWI, Lindtner RA, Vogel GF, Brunner M, Gutleben K, Blauth M, Krumschnabel G, Ebner HL (2016) Bone marrow mesenchymal stem cells from osteoporotic patients do not show altered mitochondrial energetics or ultrastructure. bioRxiv doi.org/10.1101/046300. | Human | Stem cells | Aging;senescence Other | |
Sparks 2016 Diabetologia | 2016 | Sparks LM, Gemmink A, Phielix E, Bosma M, Schaart G, Moonen-Kornips E, Jörgensen JA, Nascimento EB, Hesselink MK, Schrauwen P, Hoeks J (2016) ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity. Diabetologia 59:1030-9. | Human Mouse Rat | Skeletal muscle Other cell lines | Diabetes | |
Sheremet 2016 Biochemistry (Moscow) | 2016 | Sheremet NL, Nevinitsyna TA, Zhorzholadze NV, Ronzina IA, Itkis YS, Krylova TD, Tsygankova PG, Malakhova VA, Zakharova EY, Tokarchuk AV, Panteleeva AA, Karger EM, Lyamzaev KG, Avetisov SE (2016) Previously unclassified mutation of mtDNA m.3472T>C: evidence of pathogenicity in Leber’s hereditary optic neuropathy. Biochemistry (Moscow) BM16-078. | Human | Endothelial;epithelial;mesothelial cell Fibroblast Platelet | ||
Hamilton 2016 Physiol Rep | 2016 | Hamilton DJ, Minze LJ, Kumar T, Cao TN, Lyon CJ, Geiger PC, Hsueh WA, Gupte AA (2016) Estrogen receptor alpha activation enhances mitochondrial function and systemic metabolism in high-fat-fed ovariectomized mice. Physiol Rep 4. pii: e12913. | Mouse | Heart | ||
Liepinsh 2016 Biochem J | 2016 | Liepinsh E, Makrecka-Kuka M, Volska K, Kuka J, Makarova E, Antone U, Sevostjanovs E, Vilskersts R, Strods A, Tars K, Dambrova M (2016) Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria. Biochem J 473:1191-202. | Rat | Heart | Ischemia-reperfusion | |
Camacho-Pereira 2016 Cell Metab | 2016 | Camacho-Pereira J, Tarragó MG, Chini CC, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN (2016) CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metab 23:1127-39. | Human Mouse | Liver Lung;gill Other cell lines | Aging;senescence | |
Silva Ramos 2016 Biochim Biophys Acta | 2016 | Silva Ramos E, Larsson NG, Mourier A (2016) Bioenergetic roles of mitochondrial fusion. Biochim Biophys Acta 1857:1277-83. | Mouse | Fibroblast | ||
Raesaenen 2016 Proc Natl Acad Sci U S A | 2016 | Räsänen M, Degerman J, Nissinen TA, Miinalainen I, Kerkelä R, Siltanen A, Backman JT, Mervaala E, Hulmi JJ, Kivelä R, Alitalo K (2016) VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection. Proc Natl Acad Sci U S A 113:13144-49. | Mouse | Heart | Cancer Cardiovascular | |
Yamada 2016 J Physiol | 2016 | Yamada T, Takakura H, Jue T, Hashimoto T, Ishizawa R, Furuichi Y, Kato Y, Iwanaka N, Masuda K (2016) Myoglobin and the regulation of mitochondrial respiratory chain complex IV. J Physiol 594:483-95. | Mouse | Skeletal muscle Other cell lines | ||
Ejaz 2016 Diabetes | 2016 | Ejaz A, Martinez-Guino L, Goldfine AB, Ribas-Aulinas F, De Nigris V, Ribó S, Gonzalez-Franquesa A, Garcia-Roves PM, Li E, Dreyfuss JM, Gall W, Kim JK, Bottiglieri T, Villarroya F, Gerszten RE, Patti ME, Lerin C (2016) Dietary betaine supplementation increases Fgf21 levels to improve glucose homeostasis and reduce hepatic lipid accumulation in mice. Diabetes 65:902-12. | Mouse | Fat | Diabetes | |
Ojuka 2016 Am J Physiol Endocrinol Metab | 2016 | Ojuka E, Andrew B, Bezuidenhout N, George S, Maarman G, Madlala HP, Mendham A, Osiki PO (2016) Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates. Am J Physiol Endocrinol Metab 310:E715-23. https://doi.org/10.1152/ajpendo.00475.2015 | Human Mouse Rat | Skeletal muscle Liver | ||
Chorner 2016 Am J Physiol Regul Integr Comp Physiol | 2016 | Chorner Z, Barbeau PA, Castellani L, Wright DC, Chabowski A, Holloway GP (2016) Dietary α-linolenic acid supplementation alters skeletal muscle plasma membrane lipid composition, sarcolemmal FAT/CD36 abundance, and palmitate transport rates. Am J Physiol Regul Integr Comp Physiol 311:R1234-42. | Rat | Skeletal muscle | ||
Pambianco 2016 Cell Rep | 2016 | Pambianco S, Giovarelli M, Perrotta C, Zecchini S, Cervia D3, Di Renzo I, Moscheni C, Ripolone M, Violano R, Moggio M, Bassi MT, Puri PL, Latella L, Clementi E, De Palma C (2016) Reversal of defective mitochondrial biogenesis in limb-girdle muscular dystrophy 2D by independent modulation of histone and PGC-1α acetylation. Cell Rep 17:3010-23. | Mouse | Skeletal muscle | Other | |
Galli 2016 Am J Physiol Regul Integr Comp Physiol | 2016 | Galli GL, Crossley J, Elsey RM, Dzialowski EM, Shiels HA, Crossley DA 2nd (2016) Developmental plasticity of mitochondrial function in American alligators, Alligator mississippiensis. Am J Physiol Regul Integr Comp Physiol 311:R1164-72. | Reptiles | Heart | Oxidative stress;RONS | |
Keller 2016 Oxid Med Cell Longev | 2016 | Keller AC, Knaub LA, McClatchey PM, Connon CA, Bouchard R, Miller MW, Geary KE, Walker LA, Klemm DJ, Reusch JE (2016) Differential mitochondrial adaptation in primary vascular smooth muscle cells from a diabetic rat model. Oxid Med Cell Longev 2016:8524267. | Rat | Endothelial;epithelial;mesothelial cell | Oxidative stress;RONS | Diabetes |
Morton 2016 Nat Med | 2016 | Morton NM, Beltram J, Carter RN, Michailidou Z, Gorjanc G, McFadden C, Barrios-Llerena ME, Rodriguez-Cuenca S, Gibbins MT, Aird RE, Moreno-Navarrete JM, Munger SC, Svenson KL, Gastaldello A, Ramage L, Naredo G, Zeyda M, Wang ZV, Howie AF, Saari A, Sipilä P, Stulnig TM, Gudnason V, Kenyon CJ, Seckl JR, Walker BR, Webster SP, Dunbar DR, Churchill GA, Vidal-Puig A, Fernandez-Real JM, Emilsson V, Horvat S (2016) Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness. Nat Med 22:771-9. | Mouse | Liver | Diabetes Obesity | |
Khattar 2016 J Neurosci Methods | 2016 | Khattar NK, Yablonska S, Baranov SV, Baranova OV, Kretz ES, Larkin TM, Carlisle DL, Richardson RM, Friedlander RM (2016) Isolation of functionally active and highly purified neuronal mitochondria from human cortex. J Neurosci Methods 263:1-6. | Human Mouse | Nervous system | ||
Bonifacio 2016 Arch Toxicol | 2016 | Bonifacio A, Mullen PJ, Mityko IS, Navegantes LC, Bouitbir J, Krähenbühl S (2016) Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo. Arch Toxicol 90:203-15. doi: 10.1007/s00204-014-1378-4 | Rat | Heart | ||
Cacabelos 2016 Acta Neuropathol Commun | 2016 | Cacabelos D, Ramírez-Núñez O, Granado-Serrano AB, Torres P, Ayala V, Moiseeva V, Povedano M, Ferrer I, Pamplona R, Portero-Otin M, Boada J (2016) Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS. Acta Neuropathol Commun 4:3. | Mouse | Nervous system Other cell lines | Neurodegenerative | |
Chang 2016 Transl Res | 2016 | Chang JC, Wu SL, Liu KH, Chen YH, Chuang CS, Cheng FC, Su HL, Wei YH, Kuo SJ, Liu CS (2016) Allogeneic/xenogeneic transplantation of peptide-labeled mitochondria in Parkinson's disease: restoration of mitochondria functions and attenuation of 6-hydroxydopamine-induced neurotoxicity. Transl Res 170:40-56. | Rat | Nervous system Other cell lines | Parkinson's | |
Gilliam 2016 Am J Physiol Endocrinol Metab | 2016 | Gilliam LA, Lark DS, Reese LR, Torres MJ, Ryan TE, Lin CT, Cathey BL, Neufer PD (2016) Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction. Am J Physiol Endocrinol Metab 311:E293-301. | Mouse | Skeletal muscle | Oxidative stress;RONS | Cancer |
Brecht 2016 Toxicol In Vitro | 2016 | Brecht K, Riebel V, Couttet P, Paech F, Wolf A, Chibout SD, Pognan F, Krähenbühl S, Uteng M (2016) Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin. Toxicol In Vitro 40:55-65. | Human | Islet cell;pancreas;thymus | Cancer | |
Snook 2016 Am J Physiol Regul Integr Comp Physiol | 2016 | Snook LA, MacPherson RE, Monaco CM, Frendo-Cumbo S, Castellani L, Peppler WT, Anderson ZG, Buzelle SL, LeBlanc PJ, Holloway GP, Wright DC (2016) Prior exercise training blunts short term highfat diet induced weight gain. Am J Physiol Regul Integr Comp Physiol 311:R315-24. | Mouse | Fat | Obesity | |
Liang 2016 J Biol Chem | 2016 | Liang X, Liu L, Fu T, Zhou Q, Zhou D, Xiao L, Liu L, Kong Y, Xie H, Yi F, Lai L, Vega RB, Kelly DP, Smith SR, Gan Z (2016) Exercise inducible lactate dehydrogenase B regulates mitochondrial function in skeletal muscle. J Biol Chem 291:25306-18. | Mouse | Skeletal muscle | ||
Seiferling 2016 EMBO Rep | 2016 | Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, König T, Kukat A, Trifunovic A (2016) Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep 17:953-64. | Mouse | Heart | Cardiovascular | |
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Franko 2016 Diabetes | 2016 | Franko A, Huypens P, Neschen S, Irmler M, Rozman J, Rathkolb B, Neff F, Prehn C, Dubois G, Baumann M, Massinger R, Gradinger D, Przemeck GK, Repp B, Aichler M, Feuchtinger A, Schommers P, Stöhr O, Sanchez-Lasheras C, Adamski J, Peter A, Prokisch H, Beckers J, Walch AK, Fuchs H, Wolf E, Schubert M, Wiesner RJ, Hrabě de Angelis M (2016) Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-treated diabetic mice. Diabetes 65:2540-52. | Human | Skeletal muscle Fibroblast | Diabetes | |
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Strifler 2016 Magyar Sebeszet | 2016 | Strifler G, Meszaros A, Pecz D, Ficzere A, Barath B, Mihaly B, Hartmann P (2016) A májfunkció vizsgálata respirometriával - Examination of liver mitochondria with respirometry. Magyar Sebészet 69:194–8. | Rat | Liver | Ischemia-reperfusion | |
Wolff 2016 J Evol Biol | 2016 | Wolff JN, Pichaud N, Camus MF, Côté G, Blier PU, Dowling DK (2016) Evolutionary implications of mitochondrial genetic variation: mitochondrial genetic effects on OXPHOS respiration and mitochondrial quantity change with age and sex in fruit flies. J Evol Biol 29:736-47. | Drosophila | Skeletal muscle | Aging;senescence | |
Timpani 2016 Neurotherapeutics | 2016 | Timpani CA, Trewin AJ, Stojanovska V, Robinson A, Goodman CA, Nurgali K, Betik AC, Stepto N, Hayes A, McConell GK, Rybalka E (2016) Attempting to compensate for reduced neuronal nitric oxide synthase protein with nitrate supplementation cannot overcome metabolic dysfunction but rather has detrimental effects in Dystrophin-deficient mdx muscle. Neurotherapeutics 14:429-46. | Mouse | Skeletal muscle | Other | |
Lores-Arnaiz 2016 Neurochem Res | 2016 | Lores-Arnaiz S, Lombardi P, Karadayian AG, Orgambide F, Cicerchia D, Bustamante J (2016) Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging. Neurochem Res 41:353-63. | Mouse | Nervous system | Aging;senescence | |
Uecal 2016 J Neurotrauma | 2016 | Üçal M, Kraitsy K, Weidinger A, Paier-Pourani J, Patz S, Fink B, Molcanyi M, Schäfer U (2016) Comprehensive profiling of modulation of nitric oxide levels and mitochondrial activity in the injured brain: an experimental study based on the fluid percussion injury model in rats. J Neurotrauma 34:475-86. | Rat | Nervous system | ||
Liu 2016 EMBO Mol Med | 2016 | Liu J, Liang X, Zhou D, Lai L, Xiao L, Liu L, Fu T, Kong Y, Zhou Q, Vega RB, Zhu MS, Kelly DP, Gao X, Gan Z (2016) Coupling of mitochondrial function and skeletal muscle fiber type by a miR-499/Fnip1/AMPK circuit. EMBO Mol Med 8:1212-1228. | Mouse | Skeletal muscle | ||
Kancirova 2016 Physiol Res | 2016 | Kancirová I, Jašová M, Muráriková M, Sumbalová Z, Uličná O, Ravingerová T, Waczulíková I, Ziegelhöffer A, Ferko M (2016) Cardioprotection induced by remote ischemic preconditioning preserves the mitochondrial respiratory function in acute diabetic myocardium. Physiol Res 65:S611-19. | Rat | Heart | Ischemia-reperfusion | Diabetes |
Cannon 2016 Lung | 2016 | Cannon DT, Liu J, Sakurai R, Rossiter HB, Rehan VK (2016) Impaired lung mitochondrial respiration following perinatal nicotine exposure in rats. Lung 194:325-8. | Rat | Lung;gill | ||
Wijermars 2016 Am J Transplant | 2016 | Wijermars LG, Schaapherder AF, Kostidis S, Wüst RC, Lindeman JH (2016) Succinate accumulation and ischemia reperfusion injury: of mice but not men - A study in renal ischemia reperfusion. Am J Transplant 16:2741-6. | Human Pig Mouse Rat | Kidney | Ischemia-reperfusion Oxidative stress;RONS | |
Nissinen 2016 Sci Rep | 2016 | Nissinen TA, Degerman J, Räsänen M, Poikonen AR, Koskinen S, Mervaala E, Pasternack A, Ritvos O, Kivelä R, Hulmi JJ (2016) Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Sci Rep 6:32695. | Mouse | Skeletal muscle | Cancer | |
Maarman 2016 J Appl Physiol (1985) | 2016 | Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C2C12 myotubes. J Appl Physiol (1985) 122:1003-10. | Mouse | Skeletal muscle | ||
Pesta 2016 FASEB J | 2016 | Pesta DH, Tsirigotis DN, Befroy DE, Caballero D, Jurczak MJ, Rahimi Y, Cline GW, Dufour S, Birkenfeld AL, Rothman DL, Carpenter TO, Insogna K, Petersen KF, Bergwitz C, Shulman GI (2016) Hypophosphatemia promotes lower rates of muscle ATP synthesis. FASEB J 30:3378-87. | Mouse | Skeletal muscle | Other | |
Van Schaardenburgh 2016 PLOS ONE | 2016 | van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson EJ (2016) Mitochondrial respiration after one session of calf raise exercise in patients with peripheral vascular disease and healthy older adults. PLOS ONE 11:e0165038. | Human | Skeletal muscle | Cardiovascular | |
Lalia 2016 J Clin Endocrinol Metab | 2016 | Lalia AZ, Dasari S, Johnson ML, Robinson MM, Konopka AR, Distelmaier K, Port JD, Glavin MT, Esponda RR, Nair KS, Lanza IR (2016) Predictors of whole-body insulin sensitivity across ages and adiposity in adult humans. J Clin Endocrinol Metab 101:626-34. | Human | Skeletal muscle | Aging;senescence Diabetes Obesity | |
Kimball 2016 Thesis | 2016 | Kimball RL (2016) The role of hypoxia on pyruvate kinase M2, mammalian target of rapamycin, mitochondrial function, and cell invasion in the trophoblast. Master Thesis p55. | Human | Genital Other cell lines | Oxidative stress;RONS | Other |
Lashbrook 2016 Thesis | 2016 | Lashbrook M (2016) Functional responses of cardiac and skeletal muscle mitochondria to short-term obesity: are all obesities the same? Master's Thesis 63pp. | Mouse Other mammals | Heart Skeletal muscle | Diabetes Obesity | |
Bai 2016 PLOS ONE | 2016 | Bai F, Fink BD, Yu L, Sivitz WI (2016) Voltage-dependent regulation of Complex II energized mitochondrial oxygen flux. PLOS ONE 11:e0154982. | Mouse | Heart Skeletal muscle Nervous system Liver | Oxidative stress;RONS | |
Kilbaugh 2016 Mitochondrion | 2016 | Kilbaugh TJ, Karlsson M, Duhaime AC, Hansson MJ, Elmer E, Margulies SS (2016) Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury. Mitochondrion 26:19-25. | Pig | Nervous system | Other | |
Sirsat 2016 J Comp Physiol B | 2016 | Sirsat SK, Sirsat TS, Crossley JL, Sotherland PR, Dzialowski EM (2016) The 12-day thermoregulatory metamorphosis of Red-winged Blackbirds (Agelaius phoeniceus). J Comp Physiol B 186:651-663. | Birds | Skeletal muscle | Temperature | |
Amaral 2016 Biochim Biophys Acta | 2016 | Amaral AU, Cecatto C, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Wajner M (2016) cis-4-Decenoic and decanoic acids impair mitochondrial energy, redox and Ca2+ homeostasis and induce mitochondrial permeability transition pore opening in rat brain and liver: Possible implications for the pathogenesis of MCAD deficiency. Biochim Biophys Acta 1857:1363-72. | Rat | Nervous system Liver | Permeability transition Oxidative stress;RONS | |
Chen 2016 Nat Chem Biol | 2016 | Chen YJ, Mahieu NG, Huang X, Singh M, Crawford PA, Johnson SL, Gross RW, Schaefer J, Patti GJ (2016) Lactate metabolism is associated with mammalian mitochondria. Nat Chem Biol 12:937-43. | Human | HeLa | ||
Dechandt 2016 Anal Biochem | 2016 | Dechandt CRP, Couto-Lima CA, Alberici LC (2016) Triglyceride depletion of brown adipose tissue enables analysis of mitochondrial respiratory function in permeabilized biopsies. Anal Biochem 515:55-60. | Rat | Fat | ||
Salin 2016 J Exp Biol | 2016 | Salin K, Auer SK, Anderson GJ, Selman C, Metcalfe NB (2016) Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity. J Exp Biol 219:1356-62. | Fishes | Skeletal muscle Liver | Temperature | |
Gregg 2016 Diabetes | 2016 | Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ (2016) Pancreatic β cells from mice offset age-associated mitochondrial deficiency with reduced KATP channel activity. Diabetes 65:2700-10. | Human Mouse | Islet cell;pancreas;thymus Other cell lines | Aging;senescence | |
Johnson 2016 Diabetes | 2016 | Johnson ML, Distelmaier K, Lanza IR, Irving BA, Robinson MM, Konopka AR, Shulman GI, Nair KS (2016) Mechanism by which caloric restriction improves insulin sensitivity in sedentary obese adults. Diabetes 65:74-84. | Human | Skeletal muscle | Diabetes Obesity | |
Santos 2016 Insect Biochem Mol Biol | 2016 | Santos DE, Alberici LC, Hartfelder K (2016) Mitochondrial structure and dynamics as critical factors in honey bee (Apis mellifera L.) caste development. Insect Biochem Mol Biol 73:1-11. | Hexapods | Fat | Oxidative stress;RONS | |
Moore 2016 Cryobiology | 2016 | Moore DS, Hand SC (2016) Cryopreservation of lipid bilayers by LEA proteins from Artemia franciscana and trehalose. Cryobiology 73:240-7. | Rat | Liver | Cryopreservation | |
Reynolds 2016 Am J Physiol Endocrinol Metab | 2016 | Reynolds MS, Hancock CR, Ray JD, Kener KB, Draney C, Garland K, Hardman J, Bikman BT, Tessem JS (2016) β-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion. Am J Physiol Endocrinol Metab 311:E186-201. | Rat | Islet cell;pancreas;thymus | ||
Lark 2016 Am J Physiol Cell Physiol | 2016 | Lark DS, Torres MJ, Lin CT, Ryan TE, Anderson EJ, Neufer PD (2016) Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers. Am J Physiol Cell Physiol 311:C239-45. | Mouse | Skeletal muscle | ||
Cecatto 2016 Thesis | 2016 | Cecatto C (2016) Efeitos de acidos graxos hidroxilados de cadeia longa acumulados nas deficiencias da 3-hidroxiacil CoA desidrogenase de cadeia longa e da proteina trifunctional mitocondrial sobre a homeostase energetica mitochondrial nos musculos cardiaco e esqueletico de ratos jovens. Dissertation p103. | Rat | Heart Skeletal muscle | Permeability transition | Myopathy Cardiovascular Inherited |
Reich 2016 Thesis | 2016 | Reich V (2016) Pathophysiologie und Verfahrensentwicklung: Mechanismen der Metabolisierung von Schwefelwasserstoff im mitochondrialen Atmungskreislauf von Lungenalveolarmakrophagen. Dissertation p91. | Mouse | Macrophage-derived | Temperature | |
Smith 2016 Diabetes | 2016 | Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR (2016) Salsalate (Salicylate) uncouples mitochondria, improves glucose homeostasis, and reduces liver lipids independent of AMPK β1. Diabetes 65:3352-61. | Mouse | Skeletal muscle Liver Fat | Diabetes | |
Bal 2016 J Biol Chem | 2016 | Bal NC, Maurya SK, Singh S, Wehrens XH, Periasamy M (2016) Increased reliance on muscle based thermogenesis upon acute minimization of brown adipose tissue function. J Biol Chem 291:17247-57. | Mouse | Skeletal muscle | Temperature | |
Mizushima 2016 J Mol Cell Cardiol | 2016 | Mizushima W, Takahashi H, Watanabe M, Kinugawa S, Matsushima S, Takada S, Yokota T, Furihata T, Matsumoto J, Tsuda M, Chiba I, Nagashima S, Yanagi S, Matsumoto M, Nakayama KI, Tsutsui H, Hatakeyama S (2016) The novel heart-specific RING finger protein 207 is involved in energy metabolism in cardiomyocytes. J Mol Cell Cardiol 100:43-53. | Rat | Heart | Cardiovascular | |
Asseburg 2016 Neuromolecular Med | 2016 | Asseburg H, Schäfer C, Müller M, Hagl S, Pohland M, Berressem D, Borchiellini M, Plank C, Eckert GP (2016) Effects of grape skin extract on age-related mitochondrial dysfunction, memory and life span in C57BL/6J mice. Neuromolecular Med 18:378-95. | Mouse | Nervous system | Aging;senescence | |
Ferguson 2016 J Bioenerg Biomembr | 2016 | Ferguson MA, Sutton RM, Karlsson M, Sjövall F, Becker LB, Berg RA, Margulies SS, Kilbaugh TJ (2016) Increased platelet mitochondrial respiration after cardiac arrest and resuscitation as a potential peripheral biosignature of cerebral bioenergetic dysfunction. J Bioenerg Biomembr 48:269-79. | Pig | Nervous system Platelet | Cardiovascular | |
Xiong 2016 Hypertension | 2016 | Xiong S, Wang P, Ma L, Gao P, Gong L, Li L, Li Q, Sun F, Zhou X, He H, Chen J, Yan Z, Liu D, Zhu Z (2016) Ameliorating endothelial mitochondrial dysfunction restores coronary function via transient receptor potential vanilloid 1-mediated protein kinase A/uncoupling protein 2 pathway. Hypertension 67:451-60. | Human | Endothelial;epithelial;mesothelial cell Other cell lines | Cardiovascular | |
Ivarsson 2016 Physiol Behav | 2016 | Ivarsson N, Schiffer TA, Hernández A, Lanner JT, Weitzberg E, Lundberg JO, Westerblad H (2016) Dietary nitrate markedly improves voluntary running in mice. Physiol Behav 168:55-61. | Mouse | Skeletal muscle | ||
Diana 2016 Surg Endosc | 2016 | Diana M, Noll E, Charles AL, Diemunsch P, Geny B, Liu YY, Marchegiani F, Schiraldi L, Agnus V, Lindner V, Swanström L, Dallemagne B, Marescaux J (2016) Precision real-time evaluation of bowel perfusion: accuracy of confocal endomicroscopy assessment of stoma in a controlled hemorrhagic shock model. Surg Endosc 31:680-91. | Pig | Endothelial;epithelial;mesothelial cell | ||
Bratic 2016 PLoS Genet | 2016 | Bratic A, Clemente P, Calvo-Garrido J, Maffezzini C, Felser A, Wibom R, Wedell A, Freyer C, Wredenberg A (2016) Mitochondrial polyadenylation is a one-step process required for mRNA integrity and tRNA maturation. PLoS Genet 12:e1006028. | Drosophila | |||
Porter 2016 Cell Metab | 2016 | Porter C, Herndon DN, Chondronikola M, Chao T, Annamalai P, Bhattarai N, Saraf MK, Capek KD, Reidy PT, Daquinag AC, Kolonin MG, Rasmussen BB, Borsheim E, Toliver-Kinsky T, Sidossis LS (2016) Human and mouse brown adipose tissue mitochondria have comparable UCP1 function. Cell Metab 24:246-55. | Human Mouse | Skeletal muscle Fat | ||
Farsijani 2016 J Clin Invest | 2016 | Farsijani NM, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, Ikizler TA, O'Connor PM, Haase VH (2016) Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin. J Clin Invest 126:1425-37. | Mouse | Nervous system | Oxidative stress;RONS | |
Heinonen 2016 Hum Exp Toxicol | 2016 | Heinonen JA, Schramko AA, Skrifvars MB, Litonius E, Backman JT, Mervaala E, Rosenberg PH (2016) The effects of intravenous lipid emulsion on hemodynamic recovery and myocardial cell mitochondrial function after bupivacaine toxicity in anesthetized pigs. Hum Exp Toxicol 36:365-75. | Pig | Heart | Cardiovascular | |
Mills 2016 Cell Metab | 2016 | Mills KF, Yoshida S, Stein LR, Uchida K, Yoshino J, Imai SI (2016) Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metab 24:1–12. | Mouse | Skeletal muscle | Aging;senescence | |
Salin 2016 Physiol Biochem Zool | 2016 | Salin K, Auer SK, Rudolf AM, Anderson GJ, Selman C, Metcalfe NB (2016) Variation in metabolic rate among individuals is related to tissue-specific differences in mitochondrial LEAK respiration. Physiol Biochem Zool 89:511-23. | Fishes | Skeletal muscle Liver | ||
Timmers 2016 Diabetes Care | 2016 | Timmers S, de Ligt M, Phielix E, van de Weijer T, Hansen J, Moonen-Kornips E, Schaart G, Kunz I, Hesselink MK, Schrauwen-Hinderling VB, Schrauwen P (2016) Resveratrol as add-on therapy in subjects with well-controlled type 2 diabetes: a randomized controlled trial. Diabetes Care 39:2211-17. | Human | Skeletal muscle | Diabetes | |
Johnson 2016 Stem Cells Dev | 2016 | Johnson J, Lee W, Frazier AE, Vaghjiani V, Laskowski A, Rodriguez AL, Cagnone GL, McKenzie M, White SJ, Nisbet DR, Thorburn DR, St John JC (2016) Deletion of the complex I subunit NDUFS4 adversely modulates cellular differentiation. Stem Cells Dev 25:239-50. | Mouse | Stem cells | ||
Perna 2016 Amino Acids | 2016 | Perna MK, Kokenge AN, Miles KN, Udobi KC, Clark JF, Pyne-Geithman GJ, Khuchua Z, Skelton MR (2016) Creatine transporter deficiency leads to increased whole body and cellular metabolism. Amino Acids 48:2057-65. | Mouse | Skeletal muscle | ||
Zabielski 2016 Diabetes | 2016 | Zabielski P, Lanza IR, Gopala S, Holtz Heppelmann CJ, Bergen HR 3rd, Dasari S, Nair KS (2016) Altered skeletal muscle mitochondrial proteome as the basis of disruption of mitochondrial function in diabetic mice. Diabetes 65:561-73. | Mouse | Skeletal muscle | Oxidative stress;RONS | Diabetes |
Szczepanowska 2016 EMBO J | 2016 | Szczepanowska K, Maiti P, Kukat A, Hofsetz E, Nolte H, Senft K, Becker C, Ruzzenente B, Hornig-Do HT, Wibom R, Wiesner RJ, Krüger M, Trifunovic A (2016) CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels. EMBO J 35:2566-83. | Mouse | Heart | ||
Vevera 2016 Physiol Res | 2016 | Vevera J, Fišar Z, Nekovářová T, Vrablík M, Zlatohlávek L, Hroudová J, Singh N, Raboch J, Valeš K (2016) Statin-induced changes in mitochondrial respiration in blood platelets in rats and human with dyslipidemia. Physiol Res 65:777-88. | Human Rat | Blood cells Platelet | ||
Fisar 2016a Folia Biol (Praha) | 2016 | Fisar Z, Hroudova J (2016) Pig brain mitochondria as a biological model for study of mitochondrial respiration. Folia Biol (Praha) 62:15-25. | Pig | Nervous system | ||
Assmann 2016 Cell Rep | 2016 | Assmann N, Dettmer K, Simbuerger JM, Broeker C, Nuernberger N, Renner K, Courtneidge H, Klootwijk ED, Duerkop A, Hall A, Kleta R, Oefner PJ, Reichold M, Reinders J (2016) Renal fanconi syndrome is caused by a mistargeting-based mitochondriopathy. Cell Rep 15:1423-9. | Pig | Kidney Other cell lines | Other | |
McCourt 2016 PLOS ONE | 2016 | McCourt AC, Jakobsson L, Larsson S, Holm C, Piel S, Elmér E, Björkqvist M (2016) White adipose tissue browning in the R6/2 mouse model of Huntington's disease. PLOS ONE 11:e0159870. | Mouse | Fat | Temperature | Neurodegenerative |
Van Hoose 2016 J Nutr Biochem | 2016 | Van Hoose PM, Kelm NQ, Piell KM, Cole MP (2016) Conjugated linoleic acid and nitrite attenuate mitochondrial dysfunction during myocardial ischemia. J Nutr Biochem 34:8-16. | Mouse | Heart | Ischemia-reperfusion | Cardiovascular |
Kucera 2016 Drug Chem Toxicol | 2016 | Kučera O, Endlicher R, Rychtrmoc D, Lotková H, Sobotka O, Červinková Z (2016) Acetaminophen toxicity in rat and mouse hepatocytes in vitro. Drug Chem Toxicol 40:448-56. | Mouse Rat | Liver | ||
Hamilton 2016 Am J Physiol Heart Circ Physiol | 2016 | Hamilton DJ, Zhang A, Li S, Cao TN, Smith JA, Vedula I, Cordero-Reyes AM, Youker KA, Torre-Amione G, Gupte AA (2016) Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80. | Mouse | Heart | Oxidative stress;RONS | Cardiovascular |
Peyta 2016 Biochim Biophys Acta | 2016 | Peyta L, Jarnouen K, Pinault M, Guimaraes C, Pais de Barros JP, Chevalier S, Dumas JF, Maillot F, Hatch GM, Loyer P, Servais S (2016) Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells. Biochim Biophys Acta 1857:443-53. | Human | Liver Other cell lines | ||
Du 2016 Thesis | 2016 | Du X (2016) Anthropogenic pollution effects on mitochondrial energy metabolism, gene expression, and genotypes of natural Fundulus heteroclitus populations. Dissertation p175. | Fishes | Liver | ||
Chakraborty 2016 Pancreatology | 2016 | Chakraborty M, Hickey AJ, Petrov MS, Macdonald JR, Thompson N, Newby L, Sim D, Windsor JA, Phillips AR (2016) Mitochondrial dysfunction in peripheral blood mononuclear cells in early experimental and clinical acute pancreatitis. Pancreatology 16:739-47. | Human Rat | Blood cells | Other | |
Alleman 2016 Am J Physiol Heart Circ Physiol | 2016 | Alleman RJ, Tsang AM, Ryan TE, Patteson DJ, McClung JM, Spangenburg EE, Shaikh SR, Neufer PD, Brown DA (2016) Exercise-induced protection against reperfusion arrhythmia involves stabilization of mitochondrial energetics. Am J Physiol Heart Circ Physiol 310:H1360-70. | Rat | Heart | Ischemia-reperfusion | Cardiovascular |
Richman 2016 Nat Commun | 2016 | Richman TR, Spåhr H, Ermer JA, Davies SM, Viola HM, Bates KA, Papadimitriou J, Hool LC, Rodger J, Larsson NG, Rackham O, Filipovska A (2016) Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice. Nat Commun 7:11884. | Mouse | Heart Liver | Mitochondrial disease | |
Li 2016 J Appl Physiol (1985) | 2016 | Li C, White SH, Warren LK, Wohlgemuth SE (2016) Effects of aging on mitochondrial function in skeletal muscle of quarter horses. J Appl Physiol (1985) 121:299-311. | Horse | Skeletal muscle | Aging;senescence | |
Hagl 2016 Neuromolecular Med | 2016 | Hagl S, Asseburg H, Heinrich M, Sus N, Blumrich EM, Dringen R, Frank J, Eckert GP (2016) Effects of long-term rice bran extract supplementation on survival, cognition and brain mitochondrial function in aged NMRI mice. Neuromolecular Med 18:347-63. | Mouse | Nervous system | Aging;senescence Alzheimer's Neurodegenerative | |
Torres 2016 Redox Biol | 2016 | Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernández-Checa JC (2016) Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease. Redox Biol 11:60-72. | Human Mouse | Nervous system Liver Endothelial;epithelial;mesothelial cell Fibroblast | Other | |
Distefano 2016 J Gerontol A Biol Sci Med Sci | 2016 | Distefano G, Standley RA, Dubé JJ, Carnero EA, Ritov VB, Stefanovic-Racic M, Toledo FG, Piva SR, Goodpaster BH, Coen PM (2016) Chronological age does not influence ex-vivo mitochondrial respiration and quality control in skeletal muscle. J Gerontol A Biol Sci Med Sci 72:535-42. | Human | Skeletal muscle | Aging;senescence | |
Karlsson 2016 Shock | 2016 | Karlsson M, Hara N, Morata S, Sjövall F, Kilbaugh T, Hansson MJ, Uchino H, Elmér E (2016) Diverse and tissue-specific mitochondrial respiratory response in a mouse model of sepsis-induced multiple organ failure. Shock 45:404-10. | Mouse | Nervous system Liver | Oxidative stress;RONS | Sepsis |
Baris 2016 Am J Physiol Regul Integr Comp Physiol | 2016 | Baris TZ, Blier PU, Pichaud N, Crawford DL, Oleksiak MF (2016) Gene by environmental interactions affecting oxidative phosphorylation and thermal sensitivity. Am J Physiol Regul Integr Comp Physiol 311:R157-65. | Fishes | Heart | Temperature | |
Spendiff 2016 J Physiol | 2016 | Spendiff S, Vuda M, Gouspillou G, Aare S, Perez A, Morais JA, Jagoe RT, Filion ME, Glicksman R, Kapchinsky S, MacMillan NJ, Pion CH, Aubertin-Leheudre M, Hettwer S, Correa JA, Taivassalo T, Hepple RT (2016) Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians. J Physiol 594:7361-79. | Human Mouse | Skeletal muscle | Permeability transition | Aging;senescence Myopathy |
Ehinger 2016 Mov Disord | 2016 | Ehinger JK, Morota S, Hansson MJ, Gesine P, Elmér E (2016) Mitochondrial respiratory function in peripheral blood cells from Huntington’s disease patients. Mov Disord doi:10.1002/mdc3.12308. | Human | Blood cells Lymphocyte Platelet | Neurodegenerative | |
Cecatto 2016 Toxicol In Vitro | 2016 | Cecatto C, Godoy KD, da Silva JC, Amaral AU, Wajner M (2016) Disturbance of mitochondrial functions provoked by the major long-chain 3-hydroxylated fatty acids accumulating in MTP and LCHAD deficiencies in skeletal muscle. Toxicol In Vitro 36:1-9. | Rat | Skeletal muscle | Permeability transition | Myopathy |
Heim 2016 Thesis | 2016 | Heim A (2016) Tissue-specific seasonal changes in mitochondrial respiratory function and membrane composition in the golden-matled ground squirrel. Master's Thesis p77. | Other mammals | Heart Skeletal muscle Liver Fat | ||
Grimm 2016 Methods Mol Biol | 2016 | Grimm A, Schmitt K, Eckert A (2016) Advanced mitochondrial respiration assay for evaluation of mitochondrial dysfunction in Alzheimer's disease. Methods Mol Biol 1303:171-83. | Mouse | Nervous system | Alzheimer's | |
Van Zutphen 2016 J Hepatol | 2016 | van Zutphen T, Ciapaite J, Bloks VW, Ackereley C, Gerding A, Jurdzinski A, Allgayer de Moraes R, Zhang L, Wolters JC, Bischoff R, Wanders RJA, Houten SM, Bronte-Tinkew D, Shatseva T, Lewis GF, Groen AK, Reijngoud DJ, Bakker BM, Jonker JW, Kim PK, Bandsma RH (2016) Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction. J Hepatol 65:1198-1208. | Rat | Liver | ||
Pohland 2016 Neurochem Res | 2016 | Pohland M, Hagl S, Pellowska M, Wurglics M, Schubert-Zsilavecz M, Eckert GP (2016) MH84: a novel γ-secretase modulator/PPARγ agonist-improves mitochondrial dysfunction in a cellular model of Alzheimer's disease. Neurochem Res 41:231-42. | Human | Kidney HEK | Alzheimer's | |
Eisenberg 2016 Nat Med | 2016 | Eisenberg T, Abdellatif M, Schroeder S, Primessnig U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Magnes C, Trausinger G, Narath S, Meinitzer A, Hu Z, Kirsch A, Eller K, Carmona-Gutierrez D, Büttner S, Pietrocola F, Knittelfelder O, Schrepfer E, Rockenfeller P, Simonini C, Rahn A, Horsch M, Moreth K, Beckers J, Fuchs H, Gailus-Durner V, Neff F, Janik D, Rathkolb B, Rozman J, de Angelis MH, Moustafa T, Haemmerle G, Mayr M, Willeit P, von Frieling-Salewsky M, Pieske B, Scorrano L, Pieber T, Pechlaner R, Willeit J, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F (2016) Cardioprotection and lifespan extension by the natural polyamine spermidine. Nat Med 22:1428-38. | Mouse | Heart | Aging;senescence Cardiovascular | |
Cagnone 2016 Sci Rep | 2016 | Cagnone GL, Tsai TS, Makanji Y, Matthews P, Gould J, Bonkowski MS, Elgass KD, Wong AS, Wu LE, McKenzie M, Sinclair DA, John JC (2016) Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency. Sci Rep 6:23229. | Pig | Genital | ||
Mezera 2016 Oxid Med Cell Longev | 2016 | Mezera V, Endlicher R, Kucera O, Sobotka O, Drahota Z, Cervinkova Z (2016) Effects of epigallocatechin gallate on tert-butyl hydroperoxide-induced mitochondrial dysfunction in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 7573131:8pp. | Rat | Liver | ||
Soendergaard 2016 Eur J Sport Sci | 2016 | Søndergård SD, Dela F, Helge JW, Larsen S (2016) Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle. Eur J Sport Sci 16:801-7. | Human | Skeletal muscle | ||
Witt 2016 Metab Brain Dis | 2016 | Witt AM, Larsen FS, Bjerring PN (2016) Accumulation of lactate in the rat brain during hyperammonaemia is not associated with impaired mitochondrial respiratory capacity. Metab Brain Dis 32:461-70. | Rat | Nervous system | Other | |
Shama 2016 Evol Appl | 2016 | Shama LNS, Mark FC, Strobel A, Lokmer A, John U, Wegner KM (2016) Transgenerational effects persist down the maternal line in marine sticklebacks: gene expression matches physiology in a warming ocean. Evol Appl 10013/epic.47323. | Fishes | Heart | Temperature | |
McFarlane 2016 Thesis | 2016 | McFarlane SV (2016) Temperature-dependent alterations of brown adipose tissue metabolism during hibernation in the thirteen-lined ground squirrel, Ictidomys tridecemlineatus. Dissertation p74. | Other mammals | Fat | Temperature | |
Berressem 2016 PLOS ONE | 2016 | Berressem D, Koch K, Franke N, Klein J, Eckert GP (2016) Intravenous treatment with a long-chain omega-3 lipid emulsion provides neuroprotection in a murine model of ischemic stroke - a pilot study. PLOS ONE 11:e0167329. | Mouse | Nervous system | Ischemia-reperfusion | |
Wang 2016 Toxicol Sci | 2016 | Wang L, Espinoza HM, MacDonald JW, Bammler TK, Williams CR, Yeh A, Louie KW, Marcinek DJ, Gallagher EP (2016) Olfactory Transcriptional Analysis of Salmon Exposed to Mixtures of Chlorpyrifos and Malathion Reveal Novel Molecular Pathways of Neurobehavioral Injury. Toxicol Sci 149:145-57. | Fishes | Endothelial;epithelial;mesothelial cell | ||
Ryan 2016 J Mol Cell Cardiol | 2016 | Ryan TE, Schmidt CA, Alleman RJ, Tsang AM, Green TD, Neufer PD, Brown DA, McClung JM (2016) Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia. J Mol Cell Cardiol 97:191-6. | Mouse | Skeletal muscle | Ischemia-reperfusion | |
Layec 2016 Am J Physiol Endocrinol Metab | 2016 | Layec G, Gifford JR, Trinity JD, Hart CR, Garten RS, Park SY, Le Fur Y, Jeong EK, Richardson RS (2016) Accuracy and precision of quantitative 31P-MRS measurements of human skeletal muscle mitochondrial function. Am J Physiol Endocrinol Metab 311:E358-66. | Human | Skeletal muscle | ||
Loureiro 2016 Oxid Med Cell Longev | 2016 | Loureiro AC, do Rêgo-Monteiro IC, Louzada RA, Ortenzi VH, de Aguiar AP, de Abreu ES, Cavalcanti-de-Albuquerque JP, Hecht F, de Oliveira AC, Ceccatto VM, Fortunato RS, Carvalho DP (2016) Differential expression of NADPH oxidases depends on skeletal muscle fiber type in rats. Oxid Med Cell Longev 2016:6738701. | Rat | Skeletal muscle | ||
Moon 2016 J Biol Chem | 2016 | Moon SH, Mancuso DJ, Sims HF, Liu X, Nguyen AL, Yang K, Guan S, Dilthey BG, Jenkins CM, Weinheimer CJ, Kovacs A, Abendschein D, Gross RW (2016) Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size. J Biol Chem 291:19687-700. | Mouse | Heart | Ischemia-reperfusion | |
MiPNet17.03 Shredder vs Fibers | 2015-06-18 | Mitochondrial respiration in permeabilized fibers versus homogenate from fish liver and heart. An application study with the PBI-Shredder. | Fishes | Heart Liver | ||
Moore 2015 PhD Thesis | 2015 | Moore D (2015) Biostabilization of lipid bilayers: dealing with water stress in embryos of Artemia franciscana. PhD Thesis 1-111. | Rat | Liver | Cryopreservation | |
Bock 2015 Thesis | 2015 | Bock UB (2015) Auswirkung von normobarer Hyperoxie auf die mitochondriale Atmung von Alveolarmakrophagen. Dissertation p80. | Mouse | Lung;gill Macrophage-derived | Oxidative stress;RONS | |
Cell ergometry | 2015 | Gnaiger E (2015) Cell ergometry and OXPHOS. Mitochondr Physiol Network 2015-01-18. | ||||
Bowen 2015 Eur J Heart Fail | 2015 | Bowen TS, Rolim NP, Fischer T, Baekkerud FH, Medeiros A, Werner S, Brønstad E, Rognmo O, Mangner N, Linke A, Schuler G, Silva GJ, Wisløff U, Adams V (2015) Heart failure with preserved ejection fraction induces molecular, mitochondrial, histological, and functional alterations in rat respiratory and limb skeletal muscle. Eur J Heart Fail 17:263-72. | Rat | Skeletal muscle | Cardiovascular | |
De Andrade 2015 Exp Cell Res | 2015 | de Andrade DC, de Carvalho SN, Pinheiro D, Thole AA, Moura AS, de Carvalho L, Cortez EA (2015) Bone marrow mononuclear cell transplantation improves mitochondrial bioenergetics in the liver of cholestatic rats. Exp Cell Res 336:15-22. | Rat | Liver | Oxidative stress;RONS | Other |
Woodlief 2015 Obesity (Silver Spring) | 2015 | Woodlief TL, Carnero EA, Standley RA, Distefano G, Anthony SJ, Dubis GS, Jakicic JM, Houmard JA, Coen PM, Goodpaster BH (2015) Dose response of exercise training following roux-en-Y gastric bypass surgery: A randomized trial. Obesity (Silver Spring) 23:2454-61. | Human | Skeletal muscle | Diabetes Obesity | |
Du 2015 Aquat Toxicol | 2015 | Du X, Crawford DL, Oleksiak MF (2015) Effects of anthropogenic pollution on the oxidative phosphorylation pathway of hepatocytes from natural populations of Fundulus heteroclitus. Aquat Toxicol 165:231-40. | Fishes | Liver | ||
Porter 2015 Med Sci Sports Exerc | 2015 | Porter C, Reidy PT, Bhattarai N, Sidossis LS, Rasmussen BB (2015) Resistance exercise training alters mitochondrial function in human skeletal muscle. Med Sci Sports Exerc 47:1922-31. | Human | Skeletal muscle | ||
Ehinger 2015 J Neurol | 2015 | Ehinger JK, Morota S, Hansson MJ, Paul G, Elmér E (2015) Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients. J Neurol 262:1493-503. | Human | Blood cells Lymphocyte Platelet | Neurodegenerative Other | |
Laursen 2015 Proc Natl Acad Sci USA | 2015 | Laursen WJ, Mastrotto M, Pesta D, Funk OH, Goodman JB, Merriman DK, Ingolia N, Shulman GI, Bagriantsev SN, Gracheva EO (2015) Neuronal UCP1 expression suggests a mechanism for local thermogenesis during hibernation. Proc Natl Acad Sci USA 112:1607-12. | Other mammals | Nervous system HEK | ||
Katunga 2015 Mol Metab | 2015 | Katunga LA, Gudimella P, Efird JT, Abernathy S, Mattox TA, Beatty C, Darden TM, Thayne KA, Alwair H, Kypson AP, Virag JA, Anderson EJ (2015) Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy. Mol Metab 4:493-506. | Mouse | Heart | Cardiovascular Obesity | |
Burtscher 2015 Mitochondrion | 2015 | Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12. | Mouse | Nervous system | Neurodegenerative | |
Sjoevall 2015 US Patent | 2015 | Sjövall F, Ehinger J, Hansson M, Elmer E, Batcheller DG (2018) Mitochondrial toxicity test. US Patent US20150253306 A1. | Human | Blood cells Macrophage-derived Platelet | ||
Papazova 2015 Am J Physiol Renal Physiol | 2015 | Papazova DA, Friederich-Persson M, Joles JA, Verhaar MC (2015) Renal transplantation induces mitochondrial uncoupling, increased kidney oxygen consumption, and decreased kidney oxygen tension. Am J Physiol Renal Physiol 308:F22-8. | Rat | Kidney | Ischemia-reperfusion | |
Petrus 2015 Can J Physiol Pharmacol | 2015 | Petruş A, Duicu OM, Sturza A, Noveanu L, Kiss L, Dănilă M, Baczkó I, Muntean DM, Jost N (2015) Modulation of mitochondrial respiratory function and ROS production by novel benzopyran analogues. Can J Physiol Pharmacol 93:811-8. | Rat | Heart | Ischemia-reperfusion |