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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Contents
- 1 Mitochondrial physiology: MiP areas
- 2 Pathological states
- 3 Stress conditions
- 4 Organisms
- 5 Tissues and cells
- 6 Preparations
- 7 Enzymes
- 8 Regulation
- 9 Coupling-control states
- 10 Pathway control states
- 11 MiPMap combinations - examples
- 12 O2k-Manuals and protocols and specific instrumental applications
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (354 entries) 354 483 2 Exercise physiology;nutrition;life style 632 878 3 Comparative MiP;environmental MiP 291 428 4 Pharmacology;toxicology 670 804 5 mt-Biogenesis;mt-density 232 306 6 Genetic knockout;overexpression 504 562 7 Instruments;methods 210 314
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 227 353 2 Alzheimer's 60 81 3 Autism 3 7 4 Cancer 296 394 5 Cardiovascular 150 216 6 COPD 8 11 7 Diabetes 293 393 8 Inherited 60 81 9 Infectious 35 47 10 Myopathy 55 66 11 Neurodegenerative 145 200 12 Obesity 197 337 13 Parkinson's 52 83 14 Sepsis 61 71 15 Other 221 289
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 86 143 2 Cryopreservation 34 57 3 Hypoxia 71 103 4 Ischemia-reperfusion 291 393 5 Oxidative stress;RONS 524 730 6 Permeability transition 65 86 7 Temperature: hypothermia; hyperthermia 85 102
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 5 2 Zebrafish (» Fishes) 11 16 3 Drosophila (» Hexapods) 50 65 4 Caenorhabditis elegans (» Nematodes) 18 26 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 52 72 7 Comparative MiP 291 428
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 11 21 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 10 14 3 Amphibians frogs, toads, salamanders 9 13 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 98 128 5 Hexapods insects, springtails; » Drosophila 31 40 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 37 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 16 8 Molluscs gastropods, cephalopods, bivalves 18 28 9 Nematodes » Caenorhabditis elegans 3 8 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 15 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 48 59 12 Plants 25 45 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 30 42 14 Eubacteria true bacteria, cyanobacteria, spirochetes 23 39 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 152 213 2 Genital 80 109 3 Heart 606 787 4 Kidney 117 145 5 Liver 542 700 6 Lung;Gill 46 61 7 Nervous system 504 604 8 Skeletal muscle 913 1128
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 214 264 2 Endothelial;epithelial;mesothelial cell 217 247 3 Fibroblast 169 215 4 Islet cell;pancreas;thymus 44 54 5 Leukemia 22 25 6 Lymphocyte 48 62 7 Platelets 101 119 8 Stem cells 30 40
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 13 2 HEK 71 89 3 HeLa 29 42 4 Neuroblastoma 32 35 5 HUVEC 19 22 6 Macrophage-derived cell lines 23 32 7 Other cells and cell lines 267 304
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 40 209 2 Intact organ 21 34 3 Living cells 919 1018 4 Permeabilized cells 553 584 5 Permeabilized tissue 924 1008 6 Homogenate 289 324 7 Isolated mitochondria 1068 1337 8 SMP Submitochondrial particles 9 21 9 Chloroplasts 1 9 10 Enzyme 39 68 11 Oxidase and biochemical oxidation 37 47
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 20 24 2 Complex I CI 424 508 3 Complex II;succinate dehydrogenase CII 374 443 4 Complex III CIII 286 330 5 Complex IV;cytochrome c oxidase CIV 386 453 6 Complex V;ATP synthase CV 207 245 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 50 71 9 Supercomplex 41 54 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 75 95 11 Uncoupling protein 58 63
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 145 190 2 ATP production 71 104 3 Aerobic glycolysis 41 76 4 Amino acid 9 18 5 Calcium 86 131 6 Coupling efficiency;uncoupling 71 132 7 Cyt c Cytochrome c 38 47 8 Fatty acid FA substrate kinetics 116 140 9 Flux control 46 73 10 Inhibitor Inhibitor kinetics 128 156 11 Ion;substrate transport 52 92 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
.::: Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
95 145 13 Oxygen kinetics 95 126 14 Q-junction effect 6 7 15 Redox state 45 70 16 Substrate Fuel substrate kinetics 174 226 17 Temperature Temperature dependence 59 82 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 52 68
Coupling-control states
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2301 2497 2 R 
ROUTINE respiration
Physiological state, living cells 692 751 3 E 
ET capacity
Maximal noncoupled respiration 1585 1669 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 1973 2101
Pathway control states
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 475 569 2 N N-pathway control state NADH-linked, level 4 1937 2057 3 S S-pathway control state Succinate-linked, level 3 1297 1368 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 121 139 5 DQ Duorquinol-linked, level 2 17 21 6 CIV Complex IV single step Ascorbate & TMPD, level 1 548 574 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1203 1249 8 Other 123 139 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1103 1145
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 913 1128 2 O2k-Publications: Human heart 606 787 3 O2k-Publications: Skeletal muscle - human vs mouse 36 44
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 26 32
