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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (356 entries) 356 496 2 Exercise physiology;nutrition;life style 679 931 3 Comparative MiP;environmental MiP 301 440 4 Pharmacology;toxicology 769 909 5 mt-Biogenesis;mt-density 243 323 6 Genetic knockout;overexpression 570 631 7 Instruments;methods 235 355
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 245 379 2 Alzheimer's 65 87 3 Autism 6 10 4 Cancer 319 423 5 Cardiovascular 176 244 6 COPD 9 12 7 Diabetes 322 424 8 Inherited 61 82 9 Infectious 43 57 10 Myopathy 59 70 11 Neurodegenerative 153 211 12 Obesity 225 367 13 Parkinson's 54 86 14 Sepsis 67 77 15 Other 247 316
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 91 148 2 Cryopreservation 38 61 3 Hypoxia 85 131 4 Ischemia-reperfusion 305 409 5 Oxidative stress;RONS 546 758 6 Permeability transition 68 89 7 Temperature: hypothermia; hyperthermia 89 108
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 5 2 Zebrafish (» Fishes) 11 16 3 Drosophila (» Hexapods) 55 72 4 Caenorhabditis elegans (» Nematodes) 22 30 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 58 80 7 Comparative MiP 301 440
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 11 21 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 11 16 3 Amphibians frogs, toads, salamanders 10 15 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 106 139 5 Hexapods insects, springtails; » Drosophila 31 40 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 39 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 20 8 Molluscs gastropods, cephalopods, bivalves 22 39 9 Nematodes » Caenorhabditis elegans 5 10 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 16 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 50 61 12 Plants 29 54 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 33 45 14 Eubacteria true bacteria, cyanobacteria, spirochetes 26 45 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 163 225 2 Genital 86 116 3 Heart 654 844 4 Kidney 129 158 5 Liver 582 746 6 Lung;Gill 53 68 7 Nervous system 550 653 8 Skeletal muscle 989 1212
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 225 277 2 Endothelial;epithelial;mesothelial cell 235 266 3 Fibroblast 188 244 4 Islet cell;pancreas;thymus 46 58 5 Leukemia 22 25 6 Lymphocyte 54 69 7 Platelets 110 128 8 Stem cells 35 45
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 13 2 HEK 77 95 3 HeLa 35 50 4 Neuroblastoma 36 39 5 HUVEC 19 22 6 Macrophage-derived cell lines 25 34 7 Other cells and cell lines 279 318
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 47 228 2 Intact organ 22 35 3 Living cells 1034 1149 4 Permeabilized cells 616 649 5 Permeabilized tissue 1000 1085 6 Homogenate 324 361 7 Isolated mitochondria 1143 1424 8 SMP Submitochondrial particles 10 27 9 Chloroplasts 1 9 10 Enzyme 39 70 11 Oxidase and biochemical oxidation 38 48
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 21 25 2 Complex I CI 444 530 3 Complex II;succinate dehydrogenase CII 392 464 4 Complex III CIII 297 344 5 Complex IV;cytochrome c oxidase CIV 402 472 6 Complex V;ATP synthase CV 216 256 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 54 76 9 Supercomplex 44 60 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 77 99 11 Uncoupling protein 59 64
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 146 192 2 ATP production 73 107 3 Aerobic glycolysis 42 82 4 Amino acid 9 18 5 Calcium 94 141 6 Coupling efficiency;uncoupling 76 141 7 Cyt c Cytochrome c 40 53 8 Fatty acid FA substrate kinetics 120 144 9 Flux control 50 80 10 Inhibitor Inhibitor kinetics 127 156 11 Ion;substrate transport 55 95 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
.::: Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
100 151 13 Oxygen kinetics 99 134 14 Q-junction effect 12 54 15 Redox state 48 76 16 Substrate Fuel substrate kinetics 178 230 17 Temperature Temperature dependence 63 87 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 53 68
Coupling-control
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2538 2742 2 R 
ROUTINE respiration
Physiological state, living cells 783 860 3 E 
ET capacity
Maximal noncoupled respiration 1795 1891 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 2244 2386
Pathway control
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 533 630 2 N N-pathway control state NADH-linked, level 4 2161 2296 3 S S-pathway control state Succinate-linked, level 3 1462 1543 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 135 155 5 DQ Duorquinol-linked, level 2 20 24 6 CIV Complex IV single step Ascorbate & TMPD, level 1 607 634 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1353 1404 8 Other 126 142 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1282 1331
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 989 1212 2 O2k-Publications: Human heart 654 844 3 O2k-Publications: Skeletal muscle - human vs mouse 36 44
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 29 35