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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Contents
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (355 entries) 355 485 2 Exercise physiology;nutrition;life style 647 893 3 Comparative MiP;environmental MiP 298 437 4 Pharmacology;toxicology 720 856 5 mt-Biogenesis;mt-density 235 310 6 Genetic knockout;overexpression 536 595 7 Instruments;methods 225 331
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 239 365 2 Alzheimer's 64 85 3 Autism 5 9 4 Cancer 313 411 5 Cardiovascular 158 224 6 COPD 8 11 7 Diabetes 310 410 8 Inherited 60 81 9 Infectious 38 51 10 Myopathy 56 67 11 Neurodegenerative 148 203 12 Obesity 213 353 13 Parkinson's 52 83 14 Sepsis 62 72 15 Other 233 301
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 89 146 2 Cryopreservation 35 58 3 Hypoxia 77 110 4 Ischemia-reperfusion 298 401 5 Oxidative stress;RONS 536 745 6 Permeability transition 67 88 7 Temperature: hypothermia; hyperthermia 88 105
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 5 2 Zebrafish (» Fishes) 11 16 3 Drosophila (» Hexapods) 53 68 4 Caenorhabditis elegans (» Nematodes) 20 28 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 55 75 7 Comparative MiP 298 437
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 11 21 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 10 15 3 Amphibians frogs, toads, salamanders 10 15 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 102 132 5 Hexapods insects, springtails; » Drosophila 31 40 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 37 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 16 8 Molluscs gastropods, cephalopods, bivalves 20 30 9 Nematodes » Caenorhabditis elegans 4 9 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 15 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 48 59 12 Plants 27 47 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 32 44 14 Eubacteria true bacteria, cyanobacteria, spirochetes 24 41 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 154 215 2 Genital 82 111 3 Heart 632 816 4 Kidney 127 156 5 Liver 560 720 6 Lung;Gill 50 65 7 Nervous system 524 624 8 Skeletal muscle 944 1163
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 223 273 2 Endothelial;epithelial;mesothelial cell 228 258 3 Fibroblast 174 220 4 Islet cell;pancreas;thymus 45 57 5 Leukemia 22 25 6 Lymphocyte 49 63 7 Platelets 105 123 8 Stem cells 31 41
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 13 2 HEK 74 92 3 HeLa 31 45 4 Neuroblastoma 34 37 5 HUVEC 19 22 6 Macrophage-derived cell lines 24 33 7 Other cells and cell lines 272 309
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 46 216 2 Intact organ 21 34 3 Living cells 972 1074 4 Permeabilized cells 573 605 5 Permeabilized tissue 959 1044 6 Homogenate 305 340 7 Isolated mitochondria 1112 1389 8 SMP Submitochondrial particles 9 21 9 Chloroplasts 1 9 10 Enzyme 39 69 11 Oxidase and biochemical oxidation 38 48
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 20 24 2 Complex I CI 430 514 3 Complex II;succinate dehydrogenase CII 381 451 4 Complex III CIII 290 334 5 Complex IV;cytochrome c oxidase CIV 392 460 6 Complex V;ATP synthase CV 211 249 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 50 72 9 Supercomplex 42 55 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 76 97 11 Uncoupling protein 58 63
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 145 190 2 ATP production 72 105 3 Aerobic glycolysis 41 76 4 Amino acid 9 18 5 Calcium 89 136 6 Coupling efficiency;uncoupling 73 136 7 Cyt c Cytochrome c 38 48 8 Fatty acid FA substrate kinetics 116 140 9 Flux control 47 76 10 Inhibitor Inhibitor kinetics 127 155 11 Ion;substrate transport 55 95 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
.::: Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
99 151 13 Oxygen kinetics 97 128 14 Q-junction effect 7 10 15 Redox state 46 72 16 Substrate Fuel substrate kinetics 175 227 17 Temperature Temperature dependence 60 84 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 52 68
Coupling-control
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2406 2607 2 R ROUTINE respiration
Physiological state, living cells 736 797 3 E ET capacity
Maximal noncoupled respiration 1681 1767 4 L LEAK respiration
Resting state, non-phosphorylating respiration 2098 2231
Pathway control
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 501 597 2 N N-pathway control state NADH-linked, level 4 2040 2167 3 S S-pathway control state Succinate-linked, level 3 1368 1443 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 130 150 5 DQ Duorquinol-linked, level 2 17 21 6 CIV Complex IV single step Ascorbate & TMPD, level 1 578 605 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1271 1319 8 Other 125 141 9 ROX Residual oxygen consumption
includes non-mitochondrial respiration 1182 1224
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 944 1163 2 O2k-Publications: Human heart 632 816 3 O2k-Publications: Skeletal muscle - human vs mouse 36 44
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 27 33